Click here to switch to the map view.

The map label for this gene is yesM [H]

Identifier: 116515317

GI number: 116515317

Start: 160879

End: 162525

Strand: Direct

Name: yesM [H]

Synonym: SPD_0157

Alternate gene names: 116515317

Gene position: 160879-162525 (Clockwise)

Preceding gene: 116515665

Following gene: 116516660

Centisome position: 7.86

GC content: 40.86

Gene sequence:

>1647_bases
ATGAAGCAGTTTTGGCTACATACGCTTCTAAGAACCTATAGTTCAGTGATGATCATTATCATTGCGAGTTTTGCAATCTT
ACTCTCTTACGCTGACTGGGATTCACGTGAAAAGGAAGCCCAGAGAGTAGCCCAGCGTGTAACTGCTAGAACAGTGAGTG
AAATTGAATATTACCATAGAGAGTCAACCCAGATAGCTCAGGCTTTAGTTGAAAATCAAGCTCGTATCGAGGGAATCTAT
AAATACTTTAGCCTTAGCATGCCAGACTATTTTTACTGGCAATTAGAGCGGAAAGCTTCGCCTTATATATCAGTCTCTCT
GTATGAAAATGTTGATGACCTCTATGTTCGAAATGATTTTGTAACTGGGGTGGCCATTGCTTTTCAAGATTACAAGGAAG
TCTATGTTTCTACTAAAGACAAACGTAGTGGAGAAAAAATCAGGGCTGAGGATTTCAAACCAGCAGGAAATAGTTTTGCC
ATTCCGGTGTCAGATCCAGTGTCAGATCAAGATTTAGGAGTGATTTACATCTCCTTGGATCCTGCTGTTTTATACCATGC
CATTGATAATACTAGAGGTCATACTCCGATGGCAGTAACAGTGACCTCACCTTTTGATACGGAGATTTTTCATATTGGTG
AGACAGTTGATAGGGAGAGTGAAAATTGGCTAGTTGGCTTAACTTCTCATGGATATCAGGTTCAGGTGGCAGTTCCTAAA
AACTTTGTTTTACAAGGAACAGTGACTAGCTCTGCTTTGATTGTGGGTTTGAGCCTTCTCTTTATTGTCATTCTTTATCT
GACTTTGAGGCAGACTTTTGCTAATTACCAAAAGCAGGTAGTGGATTTAGTAGAATCCATTCAAGTCATTGCTCAAGGCG
AAGAGGGGCGTCGGATTGACATTTCCGAGAAAGATCAGGAATTACTCCTAATCGCGGAGACGACCAATGATATGTTGGAT
CGATTGGAAAAGAATATCCATGATATTTACCAGTTAGAGCTTAGTCAAAAAGATGCCAATATGCGAGCCTTGCAGGCGCA
AATCAATCCTCATTTTATGTATAATACGCTGGAGTTCTTGCGCATGTATGCAGTTATGCAGAGTCAAGATGAGTTGGCAG
ATATCATTTATGAATTCAGTAGTCTCTTGCGTAACAATATTTCCGACGAAAGAGAGACCCTCCTCAAACAGGAATTAGAA
TTTTGCCGTAAATACAGCTATCTCTGCATGGTTCGCTATCCCAAGTCCATTGCCTATGGTTTCAAGATAGATCCAGAGTT
AGAGAATATGAAGATTCCCAAGTTTACCTTGCAACCGCTGGTAGAAAACTATTTCGCGCATGGTGTTGACCACAGGCGGA
CAGATAATGTGATTAGCATCAAGGCTCTTAAACAGGATGGTTTTGTGGAAATTTTGGTGGTCGATAATGGTAGAGGAATG
TCGGCTGAAAAGTTGGCAAATATCCGAGAAAAATTAAGTCAGAAATATTTTGAACACCAAGCCAGCTACAGTGATCAAAG
GCAGTCTATCGGGATTGTCAATGTACACGAGCGTTTTGTGCTCTATTTTGGAGACCGCTATGCCATTACTATAGAGTCTG
CAGAGCAAGCCGGTGTTCAGTATCGTATTACAATTCAAGATGAGTAG

Upstream 100 bases:

>100_bases
CTGCTATTTTTTGTAGGAATTGGGATGTGGCATTTCTTTATCAGTGATATGTTGGAACCTGTCTATGAAATCATCCATGA
AAAATTGGCGACAAAATAGA

Downstream 100 bases:

>100_bases
AAAGGGAGAAAATGTATAAAGTATTATTAGTAGATGATGAGTACATGGTGACAGAAGGTCTGAAGCGTTTGATTCCCTTT
GATAAGTGGGATATGGAGGT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIY
KYFSLSMPDYFYWQLERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDRESENWLVGLTSHGYQVQVAVPK
NFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLD
RLEKNIHDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERETLLKQELE
FCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGM
SAEKLANIREKLSQKYFEHQASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE

Sequences:

>Translated_548_residues
MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIY
KYFSLSMPDYFYWQLERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDRESENWLVGLTSHGYQVQVAVPK
NFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLD
RLEKNIHDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERETLLKQELE
FCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGM
SAEKLANIREKLSQKYFEHQASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE
>Mature_548_residues
MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIY
KYFSLSMPDYFYWQLERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDRESENWLVGLTSHGYQVQVAVPK
NFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLD
RLEKNIHDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERETLLKQELE
FCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGM
SAEKLANIREKLSQKYFEHQASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=197, Percent_Identity=29.9492385786802, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788446, Length=214, Percent_Identity=24.7663551401869, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63278; Mature: 63278

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVAQRVTARTVSEIEYYHR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPYISVSLYENVDDLYVRNDF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCHHEEECCH
VTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFAIPVSDPVSDQDLGVIYISLD
HHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCCEEEEEEEC
PAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDRESENWLVGLTSHGYQVQVAVPK
HHHHHEECCCCCCCCCEEEEEECCCCCEEEECCCHHCCCCCCEEEEEECCCEEEEEECCC
NFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANYQKQVVDLVESIQVIAQGEEGRRID
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEC
ISEKDQELLLIAETTNDMLDRLEKNIHDIYQLELSQKDANMRALQAQINPHFMYNTLEFL
CCCCCCEEEEEEECHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHCCCHHHHHHHHHH
RMYAVMQSQDELADIIYEFSSLLRNNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYG
HHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHEEC
FKIDPELENMKIPKFTLQPLVENYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGM
CEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCC
SAEKLANIREKLSQKYFEHQASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQ
CHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEECCEEEEEECCEEEEEEECHHHCCCE
YRITIQDE
EEEEEECC
>Mature Secondary Structure
MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVAQRVTARTVSEIEYYHR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPYISVSLYENVDDLYVRNDF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCHHEEECCH
VTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFAIPVSDPVSDQDLGVIYISLD
HHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCCEEEEEEEC
PAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDRESENWLVGLTSHGYQVQVAVPK
HHHHHEECCCCCCCCCEEEEEECCCCCEEEECCCHHCCCCCCEEEEEECCCEEEEEECCC
NFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANYQKQVVDLVESIQVIAQGEEGRRID
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEC
ISEKDQELLLIAETTNDMLDRLEKNIHDIYQLELSQKDANMRALQAQINPHFMYNTLEFL
CCCCCCEEEEEEECHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHCCCHHHHHHHHHH
RMYAVMQSQDELADIIYEFSSLLRNNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYG
HHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHEEC
FKIDPELENMKIPKFTLQPLVENYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGM
CEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCC
SAEKLANIREKLSQKYFEHQASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQ
CHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEECCEEEEEECCEEEEEEECHHHCCCE
YRITIQDE
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]