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The map label for this gene is yhcK [H]

Identifier: 116493518

GI number: 116493518

Start: 1766854

End: 1768056

Strand: Reverse

Name: yhcK [H]

Synonym: PEPE_1790

Alternate gene names: 116493518

Gene position: 1768056-1766854 (Counterclockwise)

Preceding gene: 116493520

Following gene: 116493517

Centisome position: 96.49

GC content: 34.5

Gene sequence:

>1203_bases
ATGGAAAATACTGTAATGAATACAATCATATATTGGGCAAAAGGTTTTTTTAGTTTTAATACGGTAGTTATTGCGGCAAT
TACGGTCGGAGTATTATTCATGTTAGCTGCAGGTACCTACGTAGTTGAGATGAATATGGATAAAACAAAAACAAGTTCAA
CACTCATTGAAGAACTACTATGGGGTGTTGGTCTAACAATCGCGATGGTTTTCTTACAAAACGTGTTTACTCATTTGTAC
TCAACAATTGCTAGTAGTGAGTTAGGTTGGGAATACTCAACTGCTCAGTTTGTGGTGCTATTCTACTGCCTATATATTGT
TCATAGAAAAGTCGTACTGTGGTTTAATATTATTTTACCCATGTATGTATACGGGTTAGGGATAGTACGTGGACAAATTG
GATTTGATATTGCTCCTATTTTAGCAATCTTGGTAATTATCTTAATTTCATACACAATCTACCAGCAAAATGACACTTTG
ATTGATGAGAATGTTAAATATTACAGTACGTTAATTATGTTTGGATTAGCTTGGTGGTTTGTACTTAAGGATATTCATCA
TCTAACTATCGTCGATATTATATGCTTGACCCTGGAATTTTTAATCGCAATGTCAATCGTCCATTTTGGTAACAAAAAAG
TCAGAATGATCATGAAGCAGTATTTAAACTTGATGCAGGAAGTAGATACTGATGCGTTAACAGGGGTTTATAACCGTAAT
AGCTTCAATAAGGTTGTGAAAGGCGTATTCGAATTTTATTCTAATAATGATGCACCATTAACCATGGTAATGTTTGATAT
TGATCATTTTAAACAATTTAATGACCAATACGGTCATCAAGTTGGAGATAAAGTTTTAAGGTTGGTTGCGGATCGTTTTT
CATATGAACTTGTAGATCGTAAAGCTCATGGTCAACTATTCCGGGTTGGCGGGGAAGAATTCGCCATTATTTTTCGAGGC
CGTACTGCGGATGATTGTGAAAAAATTGTAAGAGCCATCCGCGATGATTTGGTAAAAGAAACAATTAGGGTTAATAATCA
TGATCGAATTGGAATTAAAGTTTCAATCGGTATTTCTCAATTAAGAGATGATGATTTTGATTTCCAAACATTCTACAAAC
GTGTGGATGATTATTTGTATCAATCTAAGAGAAACAAACGTAATAGTATTACGGTTGAGGGAAAGGTGGCCTCGCTAAAT
TGA

Upstream 100 bases:

>100_bases
CTTAACAAGAAAAGGACTTCAGTGTTAAAAGTATACCTATTTTTGAGGAATAGTAAATTGTTCAGAGAATAGGGGATATG
GAGTAGTAAAGGAAAAACTT

Downstream 100 bases:

>100_bases
GCGAACTTGAACAAAAATTAGAAGGAATTTGCTTCTATGAACAACCGATTTTTTTGATAGATGCGGCCGAAAAGGAAGAA
AAAAAGGTCATCGGGAGCGA

Product: Signal transduction diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MENTVMNTIIYWAKGFFSFNTVVIAAITVGVLFMLAAGTYVVEMNMDKTKTSSTLIEELLWGVGLTIAMVFLQNVFTHLY
STIASSELGWEYSTAQFVVLFYCLYIVHRKVVLWFNIILPMYVYGLGIVRGQIGFDIAPILAILVIILISYTIYQQNDTL
IDENVKYYSTLIMFGLAWWFVLKDIHHLTIVDIICLTLEFLIAMSIVHFGNKKVRMIMKQYLNLMQEVDTDALTGVYNRN
SFNKVVKGVFEFYSNNDAPLTMVMFDIDHFKQFNDQYGHQVGDKVLRLVADRFSYELVDRKAHGQLFRVGGEEFAIIFRG
RTADDCEKIVRAIRDDLVKETIRVNNHDRIGIKVSIGISQLRDDDFDFQTFYKRVDDYLYQSKRNKRNSITVEGKVASLN

Sequences:

>Translated_400_residues
MENTVMNTIIYWAKGFFSFNTVVIAAITVGVLFMLAAGTYVVEMNMDKTKTSSTLIEELLWGVGLTIAMVFLQNVFTHLY
STIASSELGWEYSTAQFVVLFYCLYIVHRKVVLWFNIILPMYVYGLGIVRGQIGFDIAPILAILVIILISYTIYQQNDTL
IDENVKYYSTLIMFGLAWWFVLKDIHHLTIVDIICLTLEFLIAMSIVHFGNKKVRMIMKQYLNLMQEVDTDALTGVYNRN
SFNKVVKGVFEFYSNNDAPLTMVMFDIDHFKQFNDQYGHQVGDKVLRLVADRFSYELVDRKAHGQLFRVGGEEFAIIFRG
RTADDCEKIVRAIRDDLVKETIRVNNHDRIGIKVSIGISQLRDDDFDFQTFYKRVDDYLYQSKRNKRNSITVEGKVASLN
>Mature_400_residues
MENTVMNTIIYWAKGFFSFNTVVIAAITVGVLFMLAAGTYVVEMNMDKTKTSSTLIEELLWGVGLTIAMVFLQNVFTHLY
STIASSELGWEYSTAQFVVLFYCLYIVHRKVVLWFNIILPMYVYGLGIVRGQIGFDIAPILAILVIILISYTIYQQNDTL
IDENVKYYSTLIMFGLAWWFVLKDIHHLTIVDIICLTLEFLIAMSIVHFGNKKVRMIMKQYLNLMQEVDTDALTGVYNRN
SFNKVVKGVFEFYSNNDAPLTMVMFDIDHFKQFNDQYGHQVGDKVLRLVADRFSYELVDRKAHGQLFRVGGEEFAIIFRG
RTADDCEKIVRAIRDDLVKETIRVNNHDRIGIKVSIGISQLRDDDFDFQTFYKRVDDYLYQSKRNKRNSITVEGKVASLN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87082007, Length=180, Percent_Identity=30.5555555555556, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786584, Length=174, Percent_Identity=29.3103448275862, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI145693134, Length=167, Percent_Identity=29.3413173652695, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787262, Length=169, Percent_Identity=30.1775147928994, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787802, Length=187, Percent_Identity=30.4812834224599, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081974, Length=173, Percent_Identity=30.0578034682081, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081881, Length=161, Percent_Identity=32.2981366459627, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787056, Length=162, Percent_Identity=30.2469135802469, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788381, Length=166, Percent_Identity=29.5180722891566, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787816, Length=161, Percent_Identity=31.6770186335404, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1787541, Length=171, Percent_Identity=28.0701754385965, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 46188; Mature: 46188

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTVMNTIIYWAKGFFSFNTVVIAAITVGVLFMLAAGTYVVEMNMDKTKTSSTLIEELL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHH
WGVGLTIAMVFLQNVFTHLYSTIASSELGWEYSTAQFVVLFYCLYIVHRKVVLWFNIILP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MYVYGLGIVRGQIGFDIAPILAILVIILISYTIYQQNDTLIDENVKYYSTLIMFGLAWWF
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHH
VLKDIHHLTIVDIICLTLEFLIAMSIVHFGNKKVRMIMKQYLNLMQEVDTDALTGVYNRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
SFNKVVKGVFEFYSNNDAPLTMVMFDIDHFKQFNDQYGHQVGDKVLRLVADRFSYELVDR
HHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAHGQLFRVGGEEFAIIFRGRTADDCEKIVRAIRDDLVKETIRVNNHDRIGIKVSIGISQ
HHCCCEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECHHH
LRDDDFDFQTFYKRVDDYLYQSKRNKRNSITVEGKVASLN
HCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC
>Mature Secondary Structure
MENTVMNTIIYWAKGFFSFNTVVIAAITVGVLFMLAAGTYVVEMNMDKTKTSSTLIEELL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHH
WGVGLTIAMVFLQNVFTHLYSTIASSELGWEYSTAQFVVLFYCLYIVHRKVVLWFNIILP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MYVYGLGIVRGQIGFDIAPILAILVIILISYTIYQQNDTLIDENVKYYSTLIMFGLAWWF
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHH
VLKDIHHLTIVDIICLTLEFLIAMSIVHFGNKKVRMIMKQYLNLMQEVDTDALTGVYNRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
SFNKVVKGVFEFYSNNDAPLTMVMFDIDHFKQFNDQYGHQVGDKVLRLVADRFSYELVDR
HHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAHGQLFRVGGEEFAIIFRGRTADDCEKIVRAIRDDLVKETIRVNNHDRIGIKVSIGISQ
HHCCCEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECHHH
LRDDDFDFQTFYKRVDDYLYQSKRNKRNSITVEGKVASLN
HCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]