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The map label for this gene is gpmA [H]

Identifier: 116493438

GI number: 116493438

Start: 1687072

End: 1687761

Strand: Reverse

Name: gpmA [H]

Synonym: PEPE_1710

Alternate gene names: 116493438

Gene position: 1687761-1687072 (Counterclockwise)

Preceding gene: 116493439

Following gene: 116493437

Centisome position: 92.11

GC content: 41.01

Gene sequence:

>690_bases
ATGGCAAAATTAGTTTTGATCCGTCATGGACAAAGTCAATGGAACTTATCAAACCAATTTACTGGTTGGGTTGATGTAGA
TCTTAGTGACGAAGGTGTTAAACAAGCACAAAACGCTGGTAAGTTAATCAAGGAAGCTGGTATCGAATTCGATCAAGCTT
ACACATCAGTATTAACTCGTGCCATCAAGACTTTGCACTATGCTTTGGAAGGTTCAGACCAACTATGGATTCCTGAAACA
AAGACATGGCGCTTAAACGAACGTCATTATGGTGCTCTTCAAGGCCAAAACAAGGCTGAAGCAGCTGAAAAATGGGGCGA
TGACCAAGTTCACACATGGCGTCGTTCATACGACGTTCTCCCTCCACTATTGGATGCAGATGATGAAGGTTCAGCAGCAA
ACGATCGTCGTTACGCTAACTTAGACCCACGTATCATTCCTGGTGGTGAAAACCTTAAGGTTACTCTTGAACGTGTTATT
CCTTTCTGGGAAGACGAAATTGCTCCTAAGTTAATCGATGGCAAGAACGTTATTATTGCTGCACATGGTAACTCACTACG
TGCATTGAGCAAGTACATCGAAAATATCTCTGATGAAGATATTATTAATCTTGAAATGGCTACTGGTGAACCAGTTGTCT
ATGACTTCAACGAAAAGCTTGAAGTACAAAGCAAAACAAAGCTTAACTAA

Upstream 100 bases:

>100_bases
TTTTGTGGAAACTTCTTCATTTTCAGTTTGTACTAATTGCTCAAAAATTGTAAAATTATAATGTTAGAAATTTAATTCAA
GAAAGAGGTATTTAAACGAT

Downstream 100 bases:

>100_bases
TTTTAGTTAAGTTCAAGAAGTCTCAATTCGGTTTGAATTGGGACTTTTTTGTTTGCTAATATTTTTGTTGCATTTGCACC
TATTTTAATATATAATAAGC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM 2; PGAM 2; Phosphoglyceromutase 2; dPGM 2 [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MAKLVLIRHGQSQWNLSNQFTGWVDVDLSDEGVKQAQNAGKLIKEAGIEFDQAYTSVLTRAIKTLHYALEGSDQLWIPET
KTWRLNERHYGALQGQNKAEAAEKWGDDQVHTWRRSYDVLPPLLDADDEGSAANDRRYANLDPRIIPGGENLKVTLERVI
PFWEDEIAPKLIDGKNVIIAAHGNSLRALSKYIENISDEDIINLEMATGEPVVYDFNEKLEVQSKTKLN

Sequences:

>Translated_229_residues
MAKLVLIRHGQSQWNLSNQFTGWVDVDLSDEGVKQAQNAGKLIKEAGIEFDQAYTSVLTRAIKTLHYALEGSDQLWIPET
KTWRLNERHYGALQGQNKAEAAEKWGDDQVHTWRRSYDVLPPLLDADDEGSAANDRRYANLDPRIIPGGENLKVTLERVI
PFWEDEIAPKLIDGKNVIIAAHGNSLRALSKYIENISDEDIINLEMATGEPVVYDFNEKLEVQSKTKLN
>Mature_228_residues
AKLVLIRHGQSQWNLSNQFTGWVDVDLSDEGVKQAQNAGKLIKEAGIEFDQAYTSVLTRAIKTLHYALEGSDQLWIPETK
TWRLNERHYGALQGQNKAEAAEKWGDDQVHTWRRSYDVLPPLLDADDEGSAANDRRYANLDPRIIPGGENLKVTLERVIP
FWEDEIAPKLIDGKNVIIAAHGNSLRALSKYIENISDEDIINLEMATGEPVVYDFNEKLEVQSKTKLN

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=221, Percent_Identity=51.131221719457, Blast_Score=249, Evalue=2e-66,
Organism=Homo sapiens, GI4505753, Length=221, Percent_Identity=51.5837104072398, Blast_Score=231, Evalue=3e-61,
Organism=Homo sapiens, GI71274132, Length=221, Percent_Identity=49.7737556561086, Blast_Score=221, Evalue=3e-58,
Organism=Homo sapiens, GI4502445, Length=222, Percent_Identity=46.8468468468468, Blast_Score=214, Evalue=4e-56,
Organism=Homo sapiens, GI40353764, Length=222, Percent_Identity=46.8468468468468, Blast_Score=214, Evalue=4e-56,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=52.7950310559006, Blast_Score=165, Evalue=3e-41,
Organism=Escherichia coli, GI1786970, Length=221, Percent_Identity=57.4660633484163, Blast_Score=268, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6322697, Length=221, Percent_Identity=52.4886877828054, Blast_Score=248, Evalue=6e-67,
Organism=Saccharomyces cerevisiae, GI6320183, Length=268, Percent_Identity=32.089552238806, Blast_Score=125, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6324516, Length=263, Percent_Identity=31.5589353612167, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324857, Length=190, Percent_Identity=27.3684210526316, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24646216, Length=222, Percent_Identity=50.9009009009009, Blast_Score=237, Evalue=5e-63,
Organism=Drosophila melanogaster, GI85725270, Length=222, Percent_Identity=49.0990990990991, Blast_Score=215, Evalue=2e-56,
Organism=Drosophila melanogaster, GI85725272, Length=222, Percent_Identity=49.0990990990991, Blast_Score=215, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24650981, Length=222, Percent_Identity=49.0990990990991, Blast_Score=215, Evalue=2e-56,
Organism=Drosophila melanogaster, GI28571815, Length=220, Percent_Identity=35.4545454545455, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI28571817, Length=220, Percent_Identity=35.4545454545455, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24648979, Length=220, Percent_Identity=35.4545454545455, Blast_Score=152, Evalue=2e-37,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 25898; Mature: 25767

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLVLIRHGQSQWNLSNQFTGWVDVDLSDEGVKQAQNAGKLIKEAGIEFDQAYTSVLTR
CCEEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AIKTLHYALEGSDQLWIPETKTWRLNERHYGALQGQNKAEAAEKWGDDQVHTWRRSYDVL
HHHHHHHHCCCCCEEECCCCCEEEECCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCC
PPLLDADDEGSAANDRRYANLDPRIIPGGENLKVTLERVIPFWEDEIAPKLIDGKNVIIA
CCCCCCCCCCCCCCCCEECCCCCEEECCCCCEEEEHHHHCCCCCHHCCCEEECCCEEEEE
AHGNSLRALSKYIENISDEDIINLEMATGEPVVYDFNEKLEVQSKTKLN
ECCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCEEECCCCCCC
>Mature Secondary Structure 
AKLVLIRHGQSQWNLSNQFTGWVDVDLSDEGVKQAQNAGKLIKEAGIEFDQAYTSVLTR
CEEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AIKTLHYALEGSDQLWIPETKTWRLNERHYGALQGQNKAEAAEKWGDDQVHTWRRSYDVL
HHHHHHHHCCCCCEEECCCCCEEEECCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCC
PPLLDADDEGSAANDRRYANLDPRIIPGGENLKVTLERVIPFWEDEIAPKLIDGKNVIIA
CCCCCCCCCCCCCCCCEECCCCCEEECCCCCEEEEHHHHCCCCCHHCCCEEECCCEEEEE
AHGNSLRALSKYIENISDEDIINLEMATGEPVVYDFNEKLEVQSKTKLN
ECCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA