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The map label for this gene is ndk [H]

Identifier: 116492814

GI number: 116492814

Start: 1046069

End: 1046494

Strand: Reverse

Name: ndk [H]

Synonym: PEPE_1051

Alternate gene names: 116492814

Gene position: 1046494-1046069 (Counterclockwise)

Preceding gene: 116492818

Following gene: 116492813

Centisome position: 57.11

GC content: 38.73

Gene sequence:

>426_bases
ATGGAACAAGAACGAATTTTAATTTTAATTAAACCAGATGGTGTTAGTTTAGGGCATATTGGGGAAGTAATTACACGTTT
AGAACTGAAAGGATATTCAATTGATGCGCTTAAAGTTACCCAAGCGACGGAAGCACAGTTGCAGCAACATTATGAAAAAT
TAGTTAATAAACCATTCTTTAAGGAAATCGAAACATATATGTTAGAAGGCAAAATCGTGGCGATGATTGCCAGTGGAACT
CATGTTATTGATGTTTTTCATCGGATGGCAGGTGCTACAGATCCGTCGGAAGCTGCTTTCGGAACCATTCGTGGAGACCT
GGGACGGGAGTGGCCAGACGGTTTACTACGTAATGTGGTGCACAGTTCTGATAGCATTGAAAATGCTGAAAAAGAAATCA
AAATTTGGTTTCCAGAATTAAACTAA

Upstream 100 bases:

>100_bases
AAATCTAAGTAAAAATGATTTTGGATCATATTACAGTGTTTATCGTATATATATTTAGTACAATAACACTAAGCCTATAC
ATGAAATGGAGGAGTTTTTG

Downstream 100 bases:

>100_bases
GATGTGTTTATAAAAAAGTAAATTACAGAAACTAGTTAATCGATGACTGATTGGCTAGTTTTTTTATATAAGAGCTCATT
ATTTTTCAGTAGCGAGAGTA

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MEQERILILIKPDGVSLGHIGEVITRLELKGYSIDALKVTQATEAQLQQHYEKLVNKPFFKEIETYMLEGKIVAMIASGT
HVIDVFHRMAGATDPSEAAFGTIRGDLGREWPDGLLRNVVHSSDSIENAEKEIKIWFPELN

Sequences:

>Translated_141_residues
MEQERILILIKPDGVSLGHIGEVITRLELKGYSIDALKVTQATEAQLQQHYEKLVNKPFFKEIETYMLEGKIVAMIASGT
HVIDVFHRMAGATDPSEAAFGTIRGDLGREWPDGLLRNVVHSSDSIENAEKEIKIWFPELN
>Mature_141_residues
MEQERILILIKPDGVSLGHIGEVITRLELKGYSIDALKVTQATEAQLQQHYEKLVNKPFFKEIETYMLEGKIVAMIASGT
HVIDVFHRMAGATDPSEAAFGTIRGDLGREWPDGLLRNVVHSSDSIENAEKEIKIWFPELN

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI4826862, Length=135, Percent_Identity=43.7037037037037, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI66392203, Length=137, Percent_Identity=45.2554744525547, Blast_Score=123, Evalue=4e-29,
Organism=Homo sapiens, GI38045913, Length=137, Percent_Identity=45.985401459854, Blast_Score=123, Evalue=4e-29,
Organism=Homo sapiens, GI66392227, Length=137, Percent_Identity=45.2554744525547, Blast_Score=123, Evalue=5e-29,
Organism=Homo sapiens, GI66392205, Length=137, Percent_Identity=45.2554744525547, Blast_Score=123, Evalue=5e-29,
Organism=Homo sapiens, GI4505409, Length=137, Percent_Identity=45.2554744525547, Blast_Score=123, Evalue=5e-29,
Organism=Homo sapiens, GI66392192, Length=137, Percent_Identity=45.2554744525547, Blast_Score=123, Evalue=5e-29,
Organism=Homo sapiens, GI4557797, Length=137, Percent_Identity=45.985401459854, Blast_Score=123, Evalue=5e-29,
Organism=Homo sapiens, GI37693993, Length=135, Percent_Identity=41.4814814814815, Blast_Score=120, Evalue=5e-28,
Organism=Escherichia coli, GI1788866, Length=139, Percent_Identity=34.5323741007194, Blast_Score=87, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17506807, Length=136, Percent_Identity=43.3823529411765, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322783, Length=136, Percent_Identity=42.6470588235294, Blast_Score=119, Evalue=1e-28,
Organism=Drosophila melanogaster, GI45549037, Length=137, Percent_Identity=43.0656934306569, Blast_Score=125, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 15845; Mature: 15845

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQERILILIKPDGVSLGHIGEVITRLELKGYSIDALKVTQATEAQLQQHYEKLVNKPFF
CCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHCCHHH
KEIETYMLEGKIVAMIASGTHVIDVFHRMAGATDPSEAAFGTIRGDLGREWPDGLLRNVV
HHHHHHHHCCEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHH
HSSDSIENAEKEIKIWFPELN
HCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MEQERILILIKPDGVSLGHIGEVITRLELKGYSIDALKVTQATEAQLQQHYEKLVNKPFF
CCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHCCHHH
KEIETYMLEGKIVAMIASGTHVIDVFHRMAGATDPSEAAFGTIRGDLGREWPDGLLRNVV
HHHHHHHHCCEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHH
HSSDSIENAEKEIKIWFPELN
HCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA