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The map label for this gene is coaA [H]

Identifier: 116492210

GI number: 116492210

Start: 454691

End: 455608

Strand: Direct

Name: coaA [H]

Synonym: PEPE_0407

Alternate gene names: 116492210

Gene position: 454691-455608 (Clockwise)

Preceding gene: 116492209

Following gene: 116492212

Centisome position: 24.81

GC content: 36.27

Gene sequence:

>918_bases
ATGGAAGCACAAGGTTATTTTGAGTTTAAGCGGGAAGATTGGCAAAATTTAGCCAAACGAGCCGAATTACCACTGACGAC
GCAACAATTAACAGATATCAAAGCTTTAAATGATCAAATTTCACTCGAAGACGTGCAAGATGTTTACGTGCCGTTAGTAC
GATTGCTCCAAAAAAAGTATGCGGATTTTGAAAAATGGAATCGTGATAAATTAGACTTTTTACAATTGCCAGTTAAAAAA
ACGCCTTTTATTATCGGTATTTCAGGGAGTGTGGCGGTTGGTAAAAGTACAACAGCACGTTTACTACAAGAACTCTTGAG
TAGCTGGTTTACGAGCTTAAAAACCCAGTTAATAACTACCGATGGATTTTTATACCCTACCGCGGAACTTAAGCGACGGA
ATATTTTAAATCGCAAAGGATTTCCCGAAAGCTATGATATGAAATCCTTAATTAAGTTTTTAAGCGACGTTAAGAGTGGT
AAAAAAGAAATTAAAGTACCGAAGTATTCTCATCAAGTTTACGATATTGTGGAAAATGAGTTTGATACGATTGATCAACC
AGATATTCTGATTGTTGAGGGGATCAACGTGCTACAGTTACCGGCTAATGAAACCATTTATGTGAGTGATTTTTTTGATT
GGTCCATTTATGTGGATGCGGATGCAAATTTAATTGAGCAATGGTTTTTAGAACGCTTCGGGGTATTGCTTGATACAGCG
TTCCATGATCCAACTAATTATTATTACAAATACGCTAAATTACCACGTTCGGAAGCTTTCGAAATGGCACATAAAATTTG
GCGAGACATTAATTTAAAAAACCTGGAAGAATTTATCTTACCGACACGGTTTAGAGCGGATATTATTCTGCATAAGACTA
CGGGACATGTAATGGATAACATTTTAGTACGAGTTTAA

Upstream 100 bases:

>100_bases
CTAGCGACGCGGAAAAAATTCAACAATCAATTTCTGAGTCTGAATAAACGAATTATCTATGCTAGAATAGACGTAATTTT
TTGAAGATGAGGAATTGGAA

Downstream 100 bases:

>100_bases
AAAGATTGCCTAGTGAGGAATAGCTCACTAGGCAATCTTTTTTATTATAGGTTATTTAGTTACTGGTAGCTAAAAGTAAA
TTATCCACATCATTAAGCTT

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MEAQGYFEFKREDWQNLAKRAELPLTTQQLTDIKALNDQISLEDVQDVYVPLVRLLQKKYADFEKWNRDKLDFLQLPVKK
TPFIIGISGSVAVGKSTTARLLQELLSSWFTSLKTQLITTDGFLYPTAELKRRNILNRKGFPESYDMKSLIKFLSDVKSG
KKEIKVPKYSHQVYDIVENEFDTIDQPDILIVEGINVLQLPANETIYVSDFFDWSIYVDADANLIEQWFLERFGVLLDTA
FHDPTNYYYKYAKLPRSEAFEMAHKIWRDINLKNLEEFILPTRFRADIILHKTTGHVMDNILVRV

Sequences:

>Translated_305_residues
MEAQGYFEFKREDWQNLAKRAELPLTTQQLTDIKALNDQISLEDVQDVYVPLVRLLQKKYADFEKWNRDKLDFLQLPVKK
TPFIIGISGSVAVGKSTTARLLQELLSSWFTSLKTQLITTDGFLYPTAELKRRNILNRKGFPESYDMKSLIKFLSDVKSG
KKEIKVPKYSHQVYDIVENEFDTIDQPDILIVEGINVLQLPANETIYVSDFFDWSIYVDADANLIEQWFLERFGVLLDTA
FHDPTNYYYKYAKLPRSEAFEMAHKIWRDINLKNLEEFILPTRFRADIILHKTTGHVMDNILVRV
>Mature_305_residues
MEAQGYFEFKREDWQNLAKRAELPLTTQQLTDIKALNDQISLEDVQDVYVPLVRLLQKKYADFEKWNRDKLDFLQLPVKK
TPFIIGISGSVAVGKSTTARLLQELLSSWFTSLKTQLITTDGFLYPTAELKRRNILNRKGFPESYDMKSLIKFLSDVKSG
KKEIKVPKYSHQVYDIVENEFDTIDQPDILIVEGINVLQLPANETIYVSDFFDWSIYVDADANLIEQWFLERFGVLLDTA
FHDPTNYYYKYAKLPRSEAFEMAHKIWRDINLKNLEEFILPTRFRADIILHKTTGHVMDNILVRV

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=304, Percent_Identity=44.078947368421, Blast_Score=269, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 35688; Mature: 35688

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAQGYFEFKREDWQNLAKRAELPLTTQQLTDIKALNDQISLEDVQDVYVPLVRLLQKKY
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
ADFEKWNRDKLDFLQLPVKKTPFIIGISGSVAVGKSTTARLLQELLSSWFTSLKTQLITT
HHHHHCCCCCHHHHHCCCCCCCEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHEEC
DGFLYPTAELKRRNILNRKGFPESYDMKSLIKFLSDVKSGKKEIKVPKYSHQVYDIVENE
CCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHH
FDTIDQPDILIVEGINVLQLPANETIYVSDFFDWSIYVDADANLIEQWFLERFGVLLDTA
CCCCCCCCEEEEECCCEEEECCCCEEEEEEEECEEEEEECCHHHHHHHHHHHHHHHHHHH
FHDPTNYYYKYAKLPRSEAFEMAHKIWRDINLKNLEEFILPTRFRADIILHKTTGHVMDN
CCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEECCHHHHHHH
ILVRV
HHHCC
>Mature Secondary Structure
MEAQGYFEFKREDWQNLAKRAELPLTTQQLTDIKALNDQISLEDVQDVYVPLVRLLQKKY
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
ADFEKWNRDKLDFLQLPVKKTPFIIGISGSVAVGKSTTARLLQELLSSWFTSLKTQLITT
HHHHHCCCCCHHHHHCCCCCCCEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHEEC
DGFLYPTAELKRRNILNRKGFPESYDMKSLIKFLSDVKSGKKEIKVPKYSHQVYDIVENE
CCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHH
FDTIDQPDILIVEGINVLQLPANETIYVSDFFDWSIYVDADANLIEQWFLERFGVLLDTA
CCCCCCCCEEEEECCCEEEECCCCEEEEEEEECEEEEEECCHHHHHHHHHHHHHHHHHHH
FHDPTNYYYKYAKLPRSEAFEMAHKIWRDINLKNLEEFILPTRFRADIILHKTTGHVMDN
CCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEECCHHHHHHH
ILVRV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA