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The map label for this gene is ywkD [H]

Identifier: 116492129

GI number: 116492129

Start: 375009

End: 375389

Strand: Direct

Name: ywkD [H]

Synonym: PEPE_0326

Alternate gene names: 116492129

Gene position: 375009-375389 (Clockwise)

Preceding gene: 116492127

Following gene: 116492130

Centisome position: 20.47

GC content: 38.32

Gene sequence:

>381_bases
ATGGAAGTTAGGGCTGTTAATCATATCGCAATTATTTGTACGGACTACGTTTTAGCTAAAGAATTTTATGTTCATAAATT
AGGGATGGAAGTAGTTGCAGAAACGGAACGCGTAGATCGAAACGACGTAAAACTAGATTTAAAATATGGAGATTTGATGT
TTGAAATTTTTATCAAACCAGACGCTCCTCAGCGGGTTTCATATCCTGAAGCAGCGGGGCTACGCCACATTTCGTTTGCT
ACGGATAACATCGAAAAAGATGTAGACTATTTACGTTCCGTCGGGATTAAAGTTGAAGATATTCGGCGGGATGAATTGAA
TCAGCAAAAGATGACGTTTTTCTTCGATCCAGATGGGTTACCTTTAGAATTACATGAATGA

Upstream 100 bases:

>100_bases
TTAAATATTGTGCTCAGGATTTGGTTCGGTAAATTAAATCAGTTGTTCTAGCTAGCCCTTCAGGCTAAAATGAAGGAAAC
AAGTTTTGGGGAGGAACCAG

Downstream 100 bases:

>100_bases
TACCAAGGCAGAGTTACGATAATTAATTTTATCGTAACTTTTTTTGTATGAAAACGTATTTTTACACATGTCTAAATTTA
AACTGTTGCAAAAATAAATA

Product: lactoylglutathione lyase related lyase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MEVRAVNHIAIICTDYVLAKEFYVHKLGMEVVAETERVDRNDVKLDLKYGDLMFEIFIKPDAPQRVSYPEAAGLRHISFA
TDNIEKDVDYLRSVGIKVEDIRRDELNQQKMTFFFDPDGLPLELHE

Sequences:

>Translated_126_residues
MEVRAVNHIAIICTDYVLAKEFYVHKLGMEVVAETERVDRNDVKLDLKYGDLMFEIFIKPDAPQRVSYPEAAGLRHISFA
TDNIEKDVDYLRSVGIKVEDIRRDELNQQKMTFFFDPDGLPLELHE
>Mature_126_residues
MEVRAVNHIAIICTDYVLAKEFYVHKLGMEVVAETERVDRNDVKLDLKYGDLMFEIFIKPDAPQRVSYPEAAGLRHISFA
TDNIEKDVDYLRSVGIKVEDIRRDELNQQKMTFFFDPDGLPLELHE

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87081697, Length=127, Percent_Identity=46.4566929133858, Blast_Score=114, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 14660; Mature: 14660

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVRAVNHIAIICTDYVLAKEFYVHKLGMEVVAETERVDRNDVKLDLKYGDLMFEIFIKP
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEECC
DAPQRVSYPEAAGLRHISFATDNIEKDVDYLRSVGIKVEDIRRDELNQQKMTFFFDPDGL
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCC
PLELHE
EEEECC
>Mature Secondary Structure
MEVRAVNHIAIICTDYVLAKEFYVHKLGMEVVAETERVDRNDVKLDLKYGDLMFEIFIKP
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEECC
DAPQRVSYPEAAGLRHISFATDNIEKDVDYLRSVGIKVEDIRRDELNQQKMTFFFDPDGL
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCC
PLELHE
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]