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The map label for this gene is rnhA [H]

Identifier: 116492108

GI number: 116492108

Start: 350024

End: 350842

Strand: Direct

Name: rnhA [H]

Synonym: PEPE_0304

Alternate gene names: 116492108

Gene position: 350024-350842 (Clockwise)

Preceding gene: 116492107

Following gene: 116492112

Centisome position: 19.1

GC content: 40.66

Gene sequence:

>819_bases
ATGGCAAAAAAAAGAAAATTTTATGCGGTAAAAAAAGGACGAAAACCAGGACTTTATTTAACGTGGGATGCAGCCAAACA
ACAGGTTGATGGTTTTGCAGGAGCGGTATATAAAAGTTTTTTGACCAAGGCAGAAGCTGAGGAATGGATGGCAACAGCTT
CTAGAAAGACCACTAGAAAAGTATCAACGCAGACTCCATCGACTGTGACCCCTTCCATTATTCTTTACACTGACGGCGGT
TCACGTAACACTGGTAATGTCCGTGGAGGGCATGTCCGTAAAGAAGATGTAGCTGCGTGGGCTTTCTTAATCCAAAAAGA
TGGTGAAAGTATTTCTGGATCCAATGGGGAATTCGGAGCTACCAACAATCGAATGGAAATTATGGCTTTAATTAACGGTC
TCCAAAAAATAATCGACCGCTATGGTGAAAAAGCAGCGGTATTAGTGGTAGCTGATTCTAAATATGTTTTGGACGCAATT
CAAAGAAATTGGTTAAGTGGATGGCAACGACGAGGTTGGAAGAAAGCTAACGGTGAAATTGTAGCTAATAAAGAACTTTG
GCAAGCGGTAGCTAGCATTCTAAAACGAATGCCTAACCTAGAGTATCGTTGGACTAAGGGACATGCTACGAATGAGGGGA
ATGTTTTTGTGGATCAATTACTAAATAAAACCATGGATAGAATGTTACGGGAACCAACCGAATTTGAAGCACCCAAAAAA
GCCGTTTCTAATCCTAAACCTAGTTTAGCGGTTCAAGATTCAACGGCTGATTTTGAGCAATTAGGGCTATTCCATAACCA
ACAAATTAGTGACGATTAA

Upstream 100 bases:

>100_bases
AATAATCATTTATAATAAGAGCTATGCTTTAAGGCAGTTGGATTAAAATAAAAATTCAACCCTTGGACATAGTTCTTTTT
TTAATTTATGAGGTGATTTA

Downstream 100 bases:

>100_bases
GTTCAAGGGTAATATTTTGATTATCAGTTTGAGAAGCAACAGCACTGAAACCAACTTGTTCAAGTAAAGTACGAGCAATG
GTGTTGTTTTTCAAGGCAGT

Product: RNase HI

Products: NA

Alternate protein names: RNase H [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MAKKRKFYAVKKGRKPGLYLTWDAAKQQVDGFAGAVYKSFLTKAEAEEWMATASRKTTRKVSTQTPSTVTPSIILYTDGG
SRNTGNVRGGHVRKEDVAAWAFLIQKDGESISGSNGEFGATNNRMEIMALINGLQKIIDRYGEKAAVLVVADSKYVLDAI
QRNWLSGWQRRGWKKANGEIVANKELWQAVASILKRMPNLEYRWTKGHATNEGNVFVDQLLNKTMDRMLREPTEFEAPKK
AVSNPKPSLAVQDSTADFEQLGLFHNQQISDD

Sequences:

>Translated_272_residues
MAKKRKFYAVKKGRKPGLYLTWDAAKQQVDGFAGAVYKSFLTKAEAEEWMATASRKTTRKVSTQTPSTVTPSIILYTDGG
SRNTGNVRGGHVRKEDVAAWAFLIQKDGESISGSNGEFGATNNRMEIMALINGLQKIIDRYGEKAAVLVVADSKYVLDAI
QRNWLSGWQRRGWKKANGEIVANKELWQAVASILKRMPNLEYRWTKGHATNEGNVFVDQLLNKTMDRMLREPTEFEAPKK
AVSNPKPSLAVQDSTADFEQLGLFHNQQISDD
>Mature_271_residues
AKKRKFYAVKKGRKPGLYLTWDAAKQQVDGFAGAVYKSFLTKAEAEEWMATASRKTTRKVSTQTPSTVTPSIILYTDGGS
RNTGNVRGGHVRKEDVAAWAFLIQKDGESISGSNGEFGATNNRMEIMALINGLQKIIDRYGEKAAVLVVADSKYVLDAIQ
RNWLSGWQRRGWKKANGEIVANKELWQAVASILKRMPNLEYRWTKGHATNEGNVFVDQLLNKTMDRMLREPTEFEAPKKA
VSNPKPSLAVQDSTADFEQLGLFHNQQISDD

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

Organism=Escherichia coli, GI1786408, Length=129, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115532542, Length=258, Percent_Identity=27.906976744186, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00075 RnaseH [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 30432; Mature: 30301

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKRKFYAVKKGRKPGLYLTWDAAKQQVDGFAGAVYKSFLTKAEAEEWMATASRKTTRK
CCCCCCCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSTQTPSTVTPSIILYTDGGSRNTGNVRGGHVRKEDVAAWAFLIQKDGESISGSNGEFGA
HCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
TNNRMEIMALINGLQKIIDRYGEKAAVLVVADSKYVLDAIQRNWLSGWQRRGWKKANGEI
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCE
VANKELWQAVASILKRMPNLEYRWTKGHATNEGNVFVDQLLNKTMDRMLREPTEFEAPKK
EECHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHH
AVSNPKPSLAVQDSTADFEQLGLFHNQQISDD
HHCCCCCCEEEECCCCCHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AKKRKFYAVKKGRKPGLYLTWDAAKQQVDGFAGAVYKSFLTKAEAEEWMATASRKTTRK
CCCCCCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSTQTPSTVTPSIILYTDGGSRNTGNVRGGHVRKEDVAAWAFLIQKDGESISGSNGEFGA
HCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
TNNRMEIMALINGLQKIIDRYGEKAAVLVVADSKYVLDAIQRNWLSGWQRRGWKKANGEI
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCE
VANKELWQAVASILKRMPNLEYRWTKGHATNEGNVFVDQLLNKTMDRMLREPTEFEAPKK
EECHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHH
AVSNPKPSLAVQDSTADFEQLGLFHNQQISDD
HHCCCCCCEEEECCCCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]