Click here to switch to the map view.

The map label for this gene is yabD [H]

Identifier: 116492071

GI number: 116492071

Start: 314719

End: 315501

Strand: Direct

Name: yabD [H]

Synonym: PEPE_0267

Alternate gene names: 116492071

Gene position: 314719-315501 (Clockwise)

Preceding gene: 116492070

Following gene: 116492072

Centisome position: 17.18

GC content: 38.83

Gene sequence:

>783_bases
ATGCATATTTTTGATTCACACACGCATTTAAATGATGATGCTTTTTGGGGCAACGAACAAAAGTATATTGAGCATGCCCA
AAAACTAGGTGTCATAGCGACTGCTCAAGTTGGTTCCAATACGGTTCTAAATGAACGAGCTATTCAGTTAGCCGAAAAAT
ATCCTCATACCTATGCCATTGTGGGGTGGCATCCAGAGGACGCTAAAGATTTTCACGAAGCTGAACGAATAAAACTATTA
GAACAGCTCCAAAACCCGAAAGTGGTAGCCTTGGGTGAAATTGGATTGGATTACCATTGGGATATTTCGCCTCAAAAGGT
TCAGCGTCAAGTTTTTGAAGAACAACTTCAAATAGCTATCGAGCAAAATTTACCAATTTCAATTCACAATCGGGATGCTA
CAGAAGATACTTATGCGATTTTAAAAAATGCTGGTGTGGATAAAATCAAGGGAGTTATGCATAGTTTTAATGGCGATGTG
GAATGGATGGAAAAGTTCTTGGATATCGGGCTTAACATTTCATTTAGTGGAGTGGCAAGTTTCAAAAAAACTAAAATAGT
CCATGAGGCAGTTCGCCAAGTGCCTTTAGATCGTATTATGGTTGAAACTGACGCTCCATATCTAGCGCCAGAACCACTCC
GTGGAAAACAAAATGAACCGGCTTTTTCACTATATGTTCTGGAGGCCTTAGCTCGGCATCGCGATATGGCACCTGATCAA
TTAGCCGAAATAACTTTTGATAATACTTGTAAATTATATGGGATTAAAAATGAAGAAAATTAA

Upstream 100 bases:

>100_bases
CCAAAACGGCGATGTTTTAGGTTAAAAAGATTTAACACAATGGGACTGGTGATGAAACAGGTGTTTTGTCCCAGCCCTTT
TTATATTCAAGGAGGCAAAA

Downstream 100 bases:

>100_bases
AGAAGTCATTGTAGTAGAAGGAAAAGATGATACTAAAAGAATCAACCTAGCTGTCAACGCTGATACCTTGGAAACTAGGG
GATCAGCGTTATCTGATGAA

Product: Mg-dependent DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MHIFDSHTHLNDDAFWGNEQKYIEHAQKLGVIATAQVGSNTVLNERAIQLAEKYPHTYAIVGWHPEDAKDFHEAERIKLL
EQLQNPKVVALGEIGLDYHWDISPQKVQRQVFEEQLQIAIEQNLPISIHNRDATEDTYAILKNAGVDKIKGVMHSFNGDV
EWMEKFLDIGLNISFSGVASFKKTKIVHEAVRQVPLDRIMVETDAPYLAPEPLRGKQNEPAFSLYVLEALARHRDMAPDQ
LAEITFDNTCKLYGIKNEEN

Sequences:

>Translated_260_residues
MHIFDSHTHLNDDAFWGNEQKYIEHAQKLGVIATAQVGSNTVLNERAIQLAEKYPHTYAIVGWHPEDAKDFHEAERIKLL
EQLQNPKVVALGEIGLDYHWDISPQKVQRQVFEEQLQIAIEQNLPISIHNRDATEDTYAILKNAGVDKIKGVMHSFNGDV
EWMEKFLDIGLNISFSGVASFKKTKIVHEAVRQVPLDRIMVETDAPYLAPEPLRGKQNEPAFSLYVLEALARHRDMAPDQ
LAEITFDNTCKLYGIKNEEN
>Mature_260_residues
MHIFDSHTHLNDDAFWGNEQKYIEHAQKLGVIATAQVGSNTVLNERAIQLAEKYPHTYAIVGWHPEDAKDFHEAERIKLL
EQLQNPKVVALGEIGLDYHWDISPQKVQRQVFEEQLQIAIEQNLPISIHNRDATEDTYAILKNAGVDKIKGVMHSFNGDV
EWMEKFLDIGLNISFSGVASFKKTKIVHEAVRQVPLDRIMVETDAPYLAPEPLRGKQNEPAFSLYVLEALARHRDMAPDQ
LAEITFDNTCKLYGIKNEEN

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=204, Percent_Identity=34.8039215686275, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI14042943, Length=263, Percent_Identity=28.5171102661597, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI225903439, Length=246, Percent_Identity=28.4552845528455, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI110349730, Length=266, Percent_Identity=28.9473684210526, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI226061853, Length=272, Percent_Identity=29.4117647058824, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI110349734, Length=266, Percent_Identity=28.1954887218045, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI226061614, Length=258, Percent_Identity=27.5193798449612, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI226061595, Length=230, Percent_Identity=30.4347826086957, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1787342, Length=195, Percent_Identity=42.5641025641026, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=31.2741312741313, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082439, Length=260, Percent_Identity=29.6153846153846, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=282, Percent_Identity=30.1418439716312, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17565396, Length=214, Percent_Identity=30.8411214953271, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71980746, Length=261, Percent_Identity=26.0536398467433, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17543026, Length=191, Percent_Identity=29.3193717277487, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221330018, Length=301, Percent_Identity=31.2292358803987, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24648690, Length=290, Percent_Identity=28.9655172413793, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24586117, Length=258, Percent_Identity=32.1705426356589, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29653; Mature: 29653

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIFDSHTHLNDDAFWGNEQKYIEHAQKLGVIATAQVGSNTVLNERAIQLAEKYPHTYAI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEE
VGWHPEDAKDFHEAERIKLLEQLQNPKVVALGEIGLDYHWDISPQKVQRQVFEEQLQIAI
EEECCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHHHHHHHHH
EQNLPISIHNRDATEDTYAILKNAGVDKIKGVMHSFNGDVEWMEKFLDIGLNISFSGVAS
HCCCCEEEECCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEHHHHH
FKKTKIVHEAVRQVPLDRIMVETDAPYLAPEPLRGKQNEPAFSLYVLEALARHRDMAPDQ
HHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
LAEITFDNTCKLYGIKNEEN
HHHCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MHIFDSHTHLNDDAFWGNEQKYIEHAQKLGVIATAQVGSNTVLNERAIQLAEKYPHTYAI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEE
VGWHPEDAKDFHEAERIKLLEQLQNPKVVALGEIGLDYHWDISPQKVQRQVFEEQLQIAI
EEECCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHHHHHHHHH
EQNLPISIHNRDATEDTYAILKNAGVDKIKGVMHSFNGDVEWMEKFLDIGLNISFSGVAS
HCCCCEEEECCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEHHHHH
FKKTKIVHEAVRQVPLDRIMVETDAPYLAPEPLRGKQNEPAFSLYVLEALARHRDMAPDQ
HHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
LAEITFDNTCKLYGIKNEEN
HHHCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]