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The map label for this gene is ywbA [H]

Identifier: 116492039

GI number: 116492039

Start: 271667

End: 272977

Strand: Direct

Name: ywbA [H]

Synonym: PEPE_0231

Alternate gene names: 116492039

Gene position: 271667-272977 (Clockwise)

Preceding gene: 116492038

Following gene: 116492040

Centisome position: 14.83

GC content: 38.98

Gene sequence:

>1311_bases
ATGAGTGACAACAATAAGACTAATGCATTTGCTGAAAAGCTAATGCCAATTGCCGGAAAAGTTGCTTCATCTCGTCACTT
GGTTGCTTTGCGTGATGGTTTTGCGCTAGTAATGCCACTGATCATTATTGGATCAGTATTCATGATTATTAGTCAGTTCC
CAATCCCCGCATATCTAAACTTGATGTCAAGTTTGTTTGGTGCAGATTGGCAAACTACGGTTGGCTGGGCTACTAATGCT
ACATTTAGTGTGATCGGAATGGTAGCTGTAATCGGTATTTCGTATGAATTAGCTAAATCATATGAAGGAATCGATGCTCT
TTCTGCAAGTATGGTTTCCTTAGCTTCATTTATGTTAACGATTCCATTGAATATAGATAAGGCAGGAGCAGCATGGGTAC
CACTAACACAATTAGGTTCAATGGGACTCTTTGAAGCTCTTCTAATCGGGTTATTCATTACTGATGCATTCGTTTGGATG
ATTCATAAAAATTGGCAATTTAAGATGCCAGACACAGTTCCACCTGCTGTAGGACATGCATTTTCATCATTAATTCCAGG
TTTTGTTATTATTTTAGGTATGTGGTTACTTCGTTTAGGTGTTAGCTTCACGGACTTTAAGACGATTCCAAATGTTATTA
CAGTAATCGTTGCTCAACCTTTGAACGTCGTTGGTGGATCAATCTTCGGTGCTCTAGTTGCTGAATTCTTCGTTGTATTC
CTTTGGTTATTTGGTATCCATGGTTCAAACATCGTTGGTGGAATCATGGCTCCAATTTGGTTAGGAAAGATGACTGAAAA
TGCTGATGCTGTTAAAGCACATAAGGCTATTCCAAACATTGCCACACAACAATTCTTTGATAACTTTGTTCACTTTGGTG
GTGCCGGTGAAACATTATCACTTGCTTTGATGTTAATGTTCTTGGCTAAATCAGAAAACTTATCAGCTATTGGTAAATTA
GCTGGTGTTCCAGGATTATTCAATATTAACGAACCAATTATCTTTGGTTTCCCAATTGTTTTGAACCCGGTTATTGCGAT
TCCATTCGTGATTGTTCCATTGATTTCAGTTATCACGACTTACTACGCAATGAAGTTCGGTTGGGTTGGTAAACCACTTG
GTGTTGCTGTTCCTTGGACAACTCCACCTTTGATTTCTGGATACCTTGCAACTGGTAAGATTTCCGGTGCAGTTATTCAA
TTAGTTAACTTAGCAATCGGTGGAGCAATCTACTATCCATTCTTCAAGATTGCTGACCGTCAAGCACTTCAGCAAGAAGC
TGAAAAACGTGCTCAAATGGCCAACAAATAA

Upstream 100 bases:

>100_bases
CGATTCCAATATTTTGGGAAAGTAATTTTAAGGTCATATCAATTATTTACTAATTCAGATTGTAATTGCTGATCAATAAA
AATTTAGGGAGGTTTTATTT

Downstream 100 bases:

>100_bases
GCCGATTACTAAAAAAATAAAAATGTGGCCAATGAGTTTAGTTAAGCTCATTTCCCGCATTTTTTATTTATCCAAGAAAC
TGCTATGCTAAATGTAGATT

Product: cellobiose-specific PTS system IIC component

Products: protein histidine; sugar phosphate

Alternate protein names: Putative PTS system EIIC component [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSDNNKTNAFAEKLMPIAGKVASSRHLVALRDGFALVMPLIIIGSVFMIISQFPIPAYLNLMSSLFGADWQTTVGWATNA
TFSVIGMVAVIGISYELAKSYEGIDALSASMVSLASFMLTIPLNIDKAGAAWVPLTQLGSMGLFEALLIGLFITDAFVWM
IHKNWQFKMPDTVPPAVGHAFSSLIPGFVIILGMWLLRLGVSFTDFKTIPNVITVIVAQPLNVVGGSIFGALVAEFFVVF
LWLFGIHGSNIVGGIMAPIWLGKMTENADAVKAHKAIPNIATQQFFDNFVHFGGAGETLSLALMLMFLAKSENLSAIGKL
AGVPGLFNINEPIIFGFPIVLNPVIAIPFVIVPLISVITTYYAMKFGWVGKPLGVAVPWTTPPLISGYLATGKISGAVIQ
LVNLAIGGAIYYPFFKIADRQALQQEAEKRAQMANK

Sequences:

>Translated_436_residues
MSDNNKTNAFAEKLMPIAGKVASSRHLVALRDGFALVMPLIIIGSVFMIISQFPIPAYLNLMSSLFGADWQTTVGWATNA
TFSVIGMVAVIGISYELAKSYEGIDALSASMVSLASFMLTIPLNIDKAGAAWVPLTQLGSMGLFEALLIGLFITDAFVWM
IHKNWQFKMPDTVPPAVGHAFSSLIPGFVIILGMWLLRLGVSFTDFKTIPNVITVIVAQPLNVVGGSIFGALVAEFFVVF
LWLFGIHGSNIVGGIMAPIWLGKMTENADAVKAHKAIPNIATQQFFDNFVHFGGAGETLSLALMLMFLAKSENLSAIGKL
AGVPGLFNINEPIIFGFPIVLNPVIAIPFVIVPLISVITTYYAMKFGWVGKPLGVAVPWTTPPLISGYLATGKISGAVIQ
LVNLAIGGAIYYPFFKIADRQALQQEAEKRAQMANK
>Mature_435_residues
SDNNKTNAFAEKLMPIAGKVASSRHLVALRDGFALVMPLIIIGSVFMIISQFPIPAYLNLMSSLFGADWQTTVGWATNAT
FSVIGMVAVIGISYELAKSYEGIDALSASMVSLASFMLTIPLNIDKAGAAWVPLTQLGSMGLFEALLIGLFITDAFVWMI
HKNWQFKMPDTVPPAVGHAFSSLIPGFVIILGMWLLRLGVSFTDFKTIPNVITVIVAQPLNVVGGSIFGALVAEFFVVFL
WLFGIHGSNIVGGIMAPIWLGKMTENADAVKAHKAIPNIATQQFFDNFVHFGGAGETLSLALMLMFLAKSENLSAIGKLA
GVPGLFNINEPIIFGFPIVLNPVIAIPFVIVPLISVITTYYAMKFGWVGKPLGVAVPWTTPPLISGYLATGKISGAVIQL
VNLAIGGAIYYPFFKIADRQALQQEAEKRAQMANK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=460, Percent_Identity=31.0869565217391, Blast_Score=190, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: 2.7.1.69

Molecular weight: Translated: 46891; Mature: 46760

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDNNKTNAFAEKLMPIAGKVASSRHLVALRDGFALVMPLIIIGSVFMIISQFPIPAYLN
CCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
LMSSLFGADWQTTVGWATNATFSVIGMVAVIGISYELAKSYEGIDALSASMVSLASFMLT
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
IPLNIDKAGAAWVPLTQLGSMGLFEALLIGLFITDAFVWMIHKNWQFKMPDTVPPAVGHA
CCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHH
FSSLIPGFVIILGMWLLRLGVSFTDFKTIPNVITVIVAQPLNVVGGSIFGALVAEFFVVF
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LWLFGIHGSNIVGGIMAPIWLGKMTENADAVKAHKAIPNIATQQFFDNFVHFGGAGETLS
HHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHH
LALMLMFLAKSENLSAIGKLAGVPGLFNINEPIIFGFPIVLNPVIAIPFVIVPLISVITT
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
YYAMKFGWVGKPLGVAVPWTTPPLISGYLATGKISGAVIQLVNLAIGGAIYYPFFKIADR
HHHHHHCCCCCCCCEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALQQEAEKRAQMANK
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]