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The map label for this gene is ilvD

Identifier: 116515300

GI number: 116515300

Start: 407759

End: 409612

Strand: Reverse

Name: ilvD

Synonym: BCc_389

Alternate gene names: 116515300

Gene position: 409612-407759 (Counterclockwise)

Preceding gene: 116515306

Following gene: 116515299

Centisome position: 98.37

GC content: 27.56

Gene sequence:

>1854_bases
ATGCCTAAATATCGTTCTTTTACAACAATAAATGGAAAAAATATGGCTGGAGCACGAGCATTATGGCGTGCAACAGGTGT
TAAAGATGCAGATTTTGGAAAACCAATTATAGCCGTTGTTAACTCTTTTACAGAATTTGTACCAGGTCATATTCATTTAC
GTGAGTTAGGTCAATTAGTTTCTAAAGAAATTGAAAAATCAGGAGGAATTGCAAAAGAATTTAACACTATTGCAATAGAT
GATGGAATAGCTATGGGACATTCTGGAATGTTATATTCTTTACCTTCTCGAGAGTTAATTGCTGATTCTATTGAATATAT
GATTCAAGCACATTGTGTTGATGCTATGGTTTGTATTTCTAATTGCGATAAAATTACACCTGGCATGTTATTAGCTGCTT
TGCGATTAAATATTCCATCTGTATTTGTTTCCGGTGGACCTATGGAATCAGGAAAAATATTAGTTAATGAAAAAATTATT
AAAATTGATTTAGTTGATGCTATGATGCATGGAGCTAATAAAAATACTTCTAATAAAAAATTATTAAACATTGAAAAATC
AGCATGTCCAACTTGTGGATCATGTTCAGGAATGTTTACAGCTAATTCTATGAATTGTTTAACTGAAGTGTTAGGTCTTT
CTTTTCCTGGAAATGGATCATTACTAGCTACTCATATTGATAGAAAAAATCTTTTTTTAAAAGCTGGAAAAATAATTGTT
AGGAATACTAAAAATTATTATGAGAATAATGATTCTTCTTTATTACCTAGAAGTATTGTTACTAAAGAAAATTTAAAAAA
TGCTATTATTTTAGATATTTCTATGGGTGGATCTTCTAATACTGTTCTTCATTTATTAGCTATGGCTTATGAAGCAAATA
TTAATTTTAAAATGATTGATATTGATCTTTTATCTAGAAAAGTTCCTCATTTATGCAAAATTTCTCCTAGTAGTTCAAAA
TATTATATGGAAGATTTTCATCGTGCTGGCGGTGTTTTTGGAATTTTATCTGAATTAAATAAAATTAATCTATTAAATAC
TTCAATATTAAACATATTACGTATGTCGTTAGAAAAAACAATAAATAAATTTGATATTTTAAAAACAAAAGATAAAAAAA
TTATTTCTTTTTATTCATCTGGACCAGGTAATAAAAAAACAATTTATCCATTTTCACAATCGTTTCGATGGAAAAAATTA
GATAAAGATCGAATAAGTGGTTGTATTCGCTCAAAAAAATATGCTTATAGCAAAGATGGTGGTTTAGCTGTATTAACAGG
TAATTTAGCAAAAAATGGTAGTATAATAAAAACAGCTGCAATAACAAATCAAAGTAGTAAGATATTTTCAGGACCAGCTA
AAGTATATGAAAGTCAAGAAGACGCAGTATATGCTATTTTAAATAATTATATTAAATCCGGTGATATAATTGTTATTCGT
TATGAAGGACCAAAAGGAGGTCCGGGAATGCAAGAAATGTTGTATCCTACAACATACTTAAAATCAATGGGATTAGATAA
AAAATGTGCATTAATTACTGATGGTCGATTTTCAGGAGGAACATCTGGGATTTCTATTGGACATATTTCTCCTGAAGCAG
CTAATAAAGGATTAATTGCTTTAGTATATGATAATGACATTATTAATATAAATATAATTGATAGAAGTTTAAAATTAAAA
ATTTCTTCTGATGAAATTAGAAAAAGAAAAGAAAAAGAAGAAAATAGAGGTATATTTGCTTATACTCCAAAAAAACGTTT
AAGAAAAATTTCTGATTCTTTAAAAATTTATAGTATGTTCGCAACTAGTGCAGATAAGGGTGCAGTAAGAAATATACATA
AAATAAATTTTTAA

Upstream 100 bases:

>100_bases
ATAGAAAATAAAATTTTTTGTTATTTTATATTTATAAATTAAAAGTTTATTTATTTAAAAAATTATTATAAAATATTTTA
TTTAAAAATGAGTAAATTTA

Downstream 100 bases:

>100_bases
TATTTTAAATATATAAATTTTTCTACATTATCAAAAGGACAAATTATATGAAAAATTTTTTTAATAAACTTTCTTTTAGA
GAAAAATTAATAGAATTAAA

Product: hypothetical protein

Products: NA

Alternate protein names: DAD

Number of amino acids: Translated: 617; Mature: 616

Protein sequence:

>617_residues
MPKYRSFTTINGKNMAGARALWRATGVKDADFGKPIIAVVNSFTEFVPGHIHLRELGQLVSKEIEKSGGIAKEFNTIAID
DGIAMGHSGMLYSLPSRELIADSIEYMIQAHCVDAMVCISNCDKITPGMLLAALRLNIPSVFVSGGPMESGKILVNEKII
KIDLVDAMMHGANKNTSNKKLLNIEKSACPTCGSCSGMFTANSMNCLTEVLGLSFPGNGSLLATHIDRKNLFLKAGKIIV
RNTKNYYENNDSSLLPRSIVTKENLKNAIILDISMGGSSNTVLHLLAMAYEANINFKMIDIDLLSRKVPHLCKISPSSSK
YYMEDFHRAGGVFGILSELNKINLLNTSILNILRMSLEKTINKFDILKTKDKKIISFYSSGPGNKKTIYPFSQSFRWKKL
DKDRISGCIRSKKYAYSKDGGLAVLTGNLAKNGSIIKTAAITNQSSKIFSGPAKVYESQEDAVYAILNNYIKSGDIIVIR
YEGPKGGPGMQEMLYPTTYLKSMGLDKKCALITDGRFSGGTSGISIGHISPEAANKGLIALVYDNDIININIIDRSLKLK
ISSDEIRKRKEKEENRGIFAYTPKKRLRKISDSLKIYSMFATSADKGAVRNIHKINF

Sequences:

>Translated_617_residues
MPKYRSFTTINGKNMAGARALWRATGVKDADFGKPIIAVVNSFTEFVPGHIHLRELGQLVSKEIEKSGGIAKEFNTIAID
DGIAMGHSGMLYSLPSRELIADSIEYMIQAHCVDAMVCISNCDKITPGMLLAALRLNIPSVFVSGGPMESGKILVNEKII
KIDLVDAMMHGANKNTSNKKLLNIEKSACPTCGSCSGMFTANSMNCLTEVLGLSFPGNGSLLATHIDRKNLFLKAGKIIV
RNTKNYYENNDSSLLPRSIVTKENLKNAIILDISMGGSSNTVLHLLAMAYEANINFKMIDIDLLSRKVPHLCKISPSSSK
YYMEDFHRAGGVFGILSELNKINLLNTSILNILRMSLEKTINKFDILKTKDKKIISFYSSGPGNKKTIYPFSQSFRWKKL
DKDRISGCIRSKKYAYSKDGGLAVLTGNLAKNGSIIKTAAITNQSSKIFSGPAKVYESQEDAVYAILNNYIKSGDIIVIR
YEGPKGGPGMQEMLYPTTYLKSMGLDKKCALITDGRFSGGTSGISIGHISPEAANKGLIALVYDNDIININIIDRSLKLK
ISSDEIRKRKEKEENRGIFAYTPKKRLRKISDSLKIYSMFATSADKGAVRNIHKINF
>Mature_616_residues
PKYRSFTTINGKNMAGARALWRATGVKDADFGKPIIAVVNSFTEFVPGHIHLRELGQLVSKEIEKSGGIAKEFNTIAIDD
GIAMGHSGMLYSLPSRELIADSIEYMIQAHCVDAMVCISNCDKITPGMLLAALRLNIPSVFVSGGPMESGKILVNEKIIK
IDLVDAMMHGANKNTSNKKLLNIEKSACPTCGSCSGMFTANSMNCLTEVLGLSFPGNGSLLATHIDRKNLFLKAGKIIVR
NTKNYYENNDSSLLPRSIVTKENLKNAIILDISMGGSSNTVLHLLAMAYEANINFKMIDIDLLSRKVPHLCKISPSSSKY
YMEDFHRAGGVFGILSELNKINLLNTSILNILRMSLEKTINKFDILKTKDKKIISFYSSGPGNKKTIYPFSQSFRWKKLD
KDRISGCIRSKKYAYSKDGGLAVLTGNLAKNGSIIKTAAITNQSSKIFSGPAKVYESQEDAVYAILNNYIKSGDIIVIRY
EGPKGGPGMQEMLYPTTYLKSMGLDKKCALITDGRFSGGTSGISIGHISPEAANKGLIALVYDNDIININIIDRSLKLKI
SSDEIRKRKEKEENRGIFAYTPKKRLRKISDSLKIYSMFATSADKGAVRNIHKINF

Specific function: Valine and isoleucine biosynthesis; fourth step. [C]

COG id: COG0129

COG function: function code EG; Dihydroxyacid dehydratase/phosphogluconate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ilvD/edd family

Homologues:

Organism=Escherichia coli, GI48994964, Length=615, Percent_Identity=65.8536585365854, Blast_Score=879, Evalue=0.0,
Organism=Escherichia coli, GI1788157, Length=545, Percent_Identity=28.8073394495413, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI2367371, Length=568, Percent_Identity=27.6408450704225, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1786464, Length=545, Percent_Identity=28.0733944954128, Blast_Score=163, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6322476, Length=611, Percent_Identity=35.0245499181669, Blast_Score=319, Evalue=9e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ILVD_BUCCC (Q056W3)

Other databases:

- EMBL:   CP000263
- RefSeq:   YP_802929.1
- STRING:   Q056W3
- EnsemblBacteria:   EBBUCT00000001396
- GeneID:   4440871
- GenomeReviews:   CP000263_GR
- KEGG:   bcc:BCc_389
- eggNOG:   COG0129
- GeneTree:   EBGT00050000008100
- HOGENOM:   HBG671001
- OMA:   NCLAETI
- BioCyc:   BAPH372461:BCC_389-MONOMER
- HAMAP:   MF_00012
- InterPro:   IPR015928
- InterPro:   IPR004404
- InterPro:   IPR000581
- InterPro:   IPR020558
- PANTHER:   PTHR21000
- TIGRFAMs:   TIGR00110

Pfam domain/function: PF00920 ILVD_EDD; SSF52016 Aconitase/3IPM_dehydase_swvl

EC number: =4.2.1.9

Molecular weight: Translated: 67860; Mature: 67729

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS00886 ILVD_EDD_1; PS00887 ILVD_EDD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKYRSFTTINGKNMAGARALWRATGVKDADFGKPIIAVVNSFTEFVPGHIHLRELGQLV
CCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHH
SKEIEKSGGIAKEFNTIAIDDGIAMGHSGMLYSLPSRELIADSIEYMIQAHCVDAMVCIS
HHHHHHCCCCCHHCCEEEEECCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
NCDKITPGMLLAALRLNIPSVFVSGGPMESGKILVNEKIIKIDLVDAMMHGANKNTSNKK
CCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEECCEEEEEEEHHHHHHCCCCCCCCCE
LLNIEKSACPTCGSCSGMFTANSMNCLTEVLGLSFPGNGSLLATHIDRKNLFLKAGKIIV
EEEECHHCCCCCCCCCCCEECCHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEECEEEE
RNTKNYYENNDSSLLPRSIVTKENLKNAIILDISMGGSSNTVLHLLAMAYEANINFKMID
ECCCHHHCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEE
IDLLSRKVPHLCKISPSSSKYYMEDFHRAGGVFGILSELNKINLLNTSILNILRMSLEKT
HHHHHCCCCCEEEECCCCCCHHHHHHHHCCCHHHHHHHCCCEEEHHHHHHHHHHHHHHHH
INKFDILKTKDKKIISFYSSGPGNKKTIYPFSQSFRWKKLDKDRISGCIRSKKYAYSKDG
HHHHHEEECCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
GLAVLTGNLAKNGSIIKTAAITNQSSKIFSGPAKVYESQEDAVYAILNNYIKSGDIIVIR
CEEEEECCCCCCCCEEEEEEECCCCCCEECCHHHHHCCCCCHHHHHHHHHHCCCCEEEEE
YEGPKGGPGMQEMLYPTTYLKSMGLDKKCALITDGRFSGGTSGISIGHISPEAANKGLIA
ECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEECCCHHHCCCCEEE
LVYDNDIININIIDRSLKLKISSDEIRKRKEKEENRGIFAYTPKKRLRKISDSLKIYSMF
EEECCCEEEEEEECCEEEEEECHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHEEEEEE
ATSADKGAVRNIHKINF
ECCCCCCHHCCEEECCC
>Mature Secondary Structure 
PKYRSFTTINGKNMAGARALWRATGVKDADFGKPIIAVVNSFTEFVPGHIHLRELGQLV
CCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHH
SKEIEKSGGIAKEFNTIAIDDGIAMGHSGMLYSLPSRELIADSIEYMIQAHCVDAMVCIS
HHHHHHCCCCCHHCCEEEEECCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
NCDKITPGMLLAALRLNIPSVFVSGGPMESGKILVNEKIIKIDLVDAMMHGANKNTSNKK
CCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEECCEEEEEEEHHHHHHCCCCCCCCCE
LLNIEKSACPTCGSCSGMFTANSMNCLTEVLGLSFPGNGSLLATHIDRKNLFLKAGKIIV
EEEECHHCCCCCCCCCCCEECCHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEECEEEE
RNTKNYYENNDSSLLPRSIVTKENLKNAIILDISMGGSSNTVLHLLAMAYEANINFKMID
ECCCHHHCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEE
IDLLSRKVPHLCKISPSSSKYYMEDFHRAGGVFGILSELNKINLLNTSILNILRMSLEKT
HHHHHCCCCCEEEECCCCCCHHHHHHHHCCCHHHHHHHCCCEEEHHHHHHHHHHHHHHHH
INKFDILKTKDKKIISFYSSGPGNKKTIYPFSQSFRWKKLDKDRISGCIRSKKYAYSKDG
HHHHHEEECCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
GLAVLTGNLAKNGSIIKTAAITNQSSKIFSGPAKVYESQEDAVYAILNNYIKSGDIIVIR
CEEEEECCCCCCCCEEEEEEECCCCCCEECCHHHHHCCCCCHHHHHHHHHHCCCCEEEEE
YEGPKGGPGMQEMLYPTTYLKSMGLDKKCALITDGRFSGGTSGISIGHISPEAANKGLIA
ECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEECCCHHHCCCCEEE
LVYDNDIININIIDRSLKLKISSDEIRKRKEKEENRGIFAYTPKKRLRKISDSLKIYSMF
EEECCCEEEEEEECCEEEEEECHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHEEEEEE
ATSADKGAVRNIHKINF
ECCCCCCHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA