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The map label for this gene is rmlC [C]

Identifier: 116327946

GI number: 116327946

Start: 1453943

End: 1454503

Strand: Direct

Name: rmlC [C]

Synonym: LBL_1235

Alternate gene names: 116327946

Gene position: 1453943-1454503 (Clockwise)

Preceding gene: 116327945

Following gene: 116327947

Centisome position: 40.23

GC content: 40.64

Gene sequence:

>561_bases
ATGCAATTTAAAAGATTTTCCATAGAAGGTCCCGTTCTAATCAAACCCAAAGTTTTTGGAGATGAACGAGGTTTTTTCTT
TGAGACTTTTAAGACGTCACTATTCGAAAGTGAGAGTATACCGACTCACTTCTCTCAAGATAACCATTCTAGATCCTCTC
GAGGAGTATTGAGGGGGATGCATCTACAAGTTCCTCCTTACGAACAAGGAAAGTTAGTCCGAGTAGTGAGAGGCAAGGTG
ATAGACGTGGTGGTGGACGTTCGGATAGGTTCTCCTAATTATGGGAAATGGTTTTCCGTGGAACTATCGGAGGAAAATAA
AAATATATTTTGGGTTCCTCCCGGATTCGCTCACGGATTTCTAACCCTAGAAGATAAAACGGATTTTTTATATAAGGTGA
CGAAAGAATATAGTCCTCAAAACGAAGTTGGAATTCGCTGGGACGATCCTACGTTAGGCATTCCTTGGAAAACCTGGTTG
TCTGATTCTGAGTTTATAGTGTCTCAAAGGGATCAAGAAACTCCTTTTCTTGCGAGCTTTAAAAGCCCATTCGTATATTA
G

Upstream 100 bases:

>100_bases
ATCTTAAGAATAATTTATTATAGTTTCGAAATAATTTTATTCGAAGGCGAAATGTCCATAGTTTTTGAAAGACCCTATCG
CCTAAAACAAGTTAATTTAT

Downstream 100 bases:

>100_bases
AATATGATTTATTATACTGGAAAAAGCGGTCAGTTAGGTTGGGAGTTGACCAAAAGATTCAAATCTTTGGATTTGGAATC
TATAGGATTTAGTAGAGAAG

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MQFKRFSIEGPVLIKPKVFGDERGFFFETFKTSLFESESIPTHFSQDNHSRSSRGVLRGMHLQVPPYEQGKLVRVVRGKV
IDVVVDVRIGSPNYGKWFSVELSEENKNIFWVPPGFAHGFLTLEDKTDFLYKVTKEYSPQNEVGIRWDDPTLGIPWKTWL
SDSEFIVSQRDQETPFLASFKSPFVY

Sequences:

>Translated_186_residues
MQFKRFSIEGPVLIKPKVFGDERGFFFETFKTSLFESESIPTHFSQDNHSRSSRGVLRGMHLQVPPYEQGKLVRVVRGKV
IDVVVDVRIGSPNYGKWFSVELSEENKNIFWVPPGFAHGFLTLEDKTDFLYKVTKEYSPQNEVGIRWDDPTLGIPWKTWL
SDSEFIVSQRDQETPFLASFKSPFVY
>Mature_186_residues
MQFKRFSIEGPVLIKPKVFGDERGFFFETFKTSLFESESIPTHFSQDNHSRSSRGVLRGMHLQVPPYEQGKLVRVVRGKV
IDVVVDVRIGSPNYGKWFSVELSEENKNIFWVPPGFAHGFLTLEDKTDFLYKVTKEYSPQNEVGIRWDDPTLGIPWKTWL
SDSEFIVSQRDQETPFLASFKSPFVY

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=173, Percent_Identity=47.9768786127168, Blast_Score=167, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17550412, Length=189, Percent_Identity=44.973544973545, Blast_Score=132, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 21577; Mature: 21577

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFKRFSIEGPVLIKPKVFGDERGFFFETFKTSLFESESIPTHFSQDNHSRSSRGVLRGM
CCCEEEECCCCEEECCEECCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHEECE
HLQVPPYEQGKLVRVVRGKVIDVVVDVRIGSPNYGKWFSVELSEENKNIFWVPPGFAHGF
EEECCCCCCCCEEEEECCEEEEEEEEEEECCCCCCCEEEEEECCCCCEEEEECCCCCCEE
LTLEDKTDFLYKVTKEYSPQNEVGIRWDDPTLGIPWKTWLSDSEFIVSQRDQETPFLASF
EEEECCCCEEEEEEHHCCCCCCCCEEECCCCCCCCHHHHCCCCEEEEECCCCCCCEEEEC
KSPFVY
CCCCCC
>Mature Secondary Structure
MQFKRFSIEGPVLIKPKVFGDERGFFFETFKTSLFESESIPTHFSQDNHSRSSRGVLRGM
CCCEEEECCCCEEECCEECCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHEECE
HLQVPPYEQGKLVRVVRGKVIDVVVDVRIGSPNYGKWFSVELSEENKNIFWVPPGFAHGF
EEECCCCCCCCEEEEECCEEEEEEEEEEECCCCCCCEEEEEECCCCCEEEEECCCCCCEE
LTLEDKTDFLYKVTKEYSPQNEVGIRWDDPTLGIPWKTWLSDSEFIVSQRDQETPFLASF
EEEECCCCEEEEEEHHCCCCCCCCEEECCCCCCCCHHHHCCCCEEEEECCCCCCCEEEEC
KSPFVY
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]