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The map label for this gene is eryC1 [H]

Identifier: 116327942

GI number: 116327942

Start: 1447606

End: 1448697

Strand: Direct

Name: eryC1 [H]

Synonym: LBL_1231

Alternate gene names: 116327942

Gene position: 1447606-1448697 (Clockwise)

Preceding gene: 116327941

Following gene: 116327943

Centisome position: 40.05

GC content: 36.63

Gene sequence:

>1092_bases
ATGATCGAATATGAAAATCTGCGTTTAGCGAATACACGGTTCTTTGAAGAGTATAAAACGCGGCTTTCTGAAACCATCCA
AAGCGGGTGGTATATATTAGGGAAGGAAGTTTCTAGTTTTGAAAATCAATTCGCCCAATACAATGGAAACCAGTATTGTA
TAGGAGTAGGGAATGGTTTGGATGCACTTATACTCGCCTTGAAAGCGTTAAACATAGAAAAAGACTCCGAAATTATAGTT
CCTTCGAATACTTATATAGCATCTATTTTAGCGATTTTGCATGCAGGTTTGAGACCTATCTTAGTTGAACCGGATATTAG
AACCTATAATATCGATCCCGAAAGAATAGAGGAAAAAATTAATTCCAGAACGAAAGGAATTCTGATTGTACATTTGTATG
GTAAACCTTGCGAGATGGACTCTATTTTGAAGATTAAGGAAAAAAATAATCTGTTTTTAGTAGAGGATTGTGCACAATCT
CACGGCGCTTTGTATAAGGGGAAGAAAACGGGAACGTTTGGAGAAATTAACGGGTTCAGTTTTTATCCCACTAAAAACTT
GGGGGCTATTGGAGATGCGGGAGCTGTCGTGACGGATAACGATCTATATCACGACGAAGTTAAGAAACTAAGAAATTACG
GTTCTTCGATCAAGTACAAGAATGATTTACTCGGTTATAATTCTCGTTTAGATGAATTGCAGGCTATAATCTTAAATATC
AAGTTGAAATATTTGGATGCAATGAACGAACATAAAAGAAATTTAGCCAAGATTTATCTGGAAAATCTAAAAGACGATTT
TATAAAACCGGTAATTGACGAAGGAACTTACGACGTATATCATATCTTTAATGTTCGCCATACAAGACGTGACGGGCTGC
GAGACTATCTTCTAAAAAACGGCGTAAAGACTGAAATTCATTATCCGATTCCGCCTCATAAACAAGTTGCAATGAAGGAC
GTATTTACATATGTAGAAGGCGAGTTTGCTATCTCCGAGGAGGTTCATCGTACTACGCTCAGTCTTCCAATCTCAACTTT
TCACACTAAAAACGATATTTATAAAGTCGTCGAGATCATGAATAGATTTTGA

Upstream 100 bases:

>100_bases
CTGGTTGTGTTCTTCTTGTTGCTGCTTCCGATTATTATAGAGAAGACGACTACATAAGAAATTATTCTGATTTTATCCGT
TTGGCGGAGAAAAATTCGAT

Downstream 100 bases:

>100_bases
AAAAAGATTTGAATAAAATCAAGAGTATCTACTACAAAATAAAAATCGATTCCTTTTTGAGGAATACTTTTTTAGAAACA
AAAGAGGAAAATGATTTAGA

Product: sugar pyridoxal-phosphate-dependent aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MIEYENLRLANTRFFEEYKTRLSETIQSGWYILGKEVSSFENQFAQYNGNQYCIGVGNGLDALILALKALNIEKDSEIIV
PSNTYIASILAILHAGLRPILVEPDIRTYNIDPERIEEKINSRTKGILIVHLYGKPCEMDSILKIKEKNNLFLVEDCAQS
HGALYKGKKTGTFGEINGFSFYPTKNLGAIGDAGAVVTDNDLYHDEVKKLRNYGSSIKYKNDLLGYNSRLDELQAIILNI
KLKYLDAMNEHKRNLAKIYLENLKDDFIKPVIDEGTYDVYHIFNVRHTRRDGLRDYLLKNGVKTEIHYPIPPHKQVAMKD
VFTYVEGEFAISEEVHRTTLSLPISTFHTKNDIYKVVEIMNRF

Sequences:

>Translated_363_residues
MIEYENLRLANTRFFEEYKTRLSETIQSGWYILGKEVSSFENQFAQYNGNQYCIGVGNGLDALILALKALNIEKDSEIIV
PSNTYIASILAILHAGLRPILVEPDIRTYNIDPERIEEKINSRTKGILIVHLYGKPCEMDSILKIKEKNNLFLVEDCAQS
HGALYKGKKTGTFGEINGFSFYPTKNLGAIGDAGAVVTDNDLYHDEVKKLRNYGSSIKYKNDLLGYNSRLDELQAIILNI
KLKYLDAMNEHKRNLAKIYLENLKDDFIKPVIDEGTYDVYHIFNVRHTRRDGLRDYLLKNGVKTEIHYPIPPHKQVAMKD
VFTYVEGEFAISEEVHRTTLSLPISTFHTKNDIYKVVEIMNRF
>Mature_363_residues
MIEYENLRLANTRFFEEYKTRLSETIQSGWYILGKEVSSFENQFAQYNGNQYCIGVGNGLDALILALKALNIEKDSEIIV
PSNTYIASILAILHAGLRPILVEPDIRTYNIDPERIEEKINSRTKGILIVHLYGKPCEMDSILKIKEKNNLFLVEDCAQS
HGALYKGKKTGTFGEINGFSFYPTKNLGAIGDAGAVVTDNDLYHDEVKKLRNYGSSIKYKNDLLGYNSRLDELQAIILNI
KLKYLDAMNEHKRNLAKIYLENLKDDFIKPVIDEGTYDVYHIFNVRHTRRDGLRDYLLKNGVKTEIHYPIPPHKQVAMKD
VFTYVEGEFAISEEVHRTTLSLPISTFHTKNDIYKVVEIMNRF

Specific function: Sensor protein that transfers the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of erythromycin biosynthesis genes (Potential) [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=307, Percent_Identity=29.6416938110749, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI2367285, Length=300, Percent_Identity=30.6666666666667, Blast_Score=121, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 41673; Mature: 41673

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEYENLRLANTRFFEEYKTRLSETIQSGWYILGKEVSSFENQFAQYNGNQYCIGVGNGL
CCCCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCEEEEECCCCH
DALILALKALNIEKDSEIIVPSNTYIASILAILHAGLRPILVEPDIRTYNIDPERIEEKI
HHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHCCCCCEEECCCCEEECCCHHHHHHHH
NSRTKGILIVHLYGKPCEMDSILKIKEKNNLFLVEDCAQSHGALYKGKKTGTFGEINGFS
CCCCCCEEEEEEECCCCCCCHHEEEECCCCEEEEEHHHHHCCCEEECCCCCCCCCCCCEE
FYPTKNLGAIGDAGAVVTDNDLYHDEVKKLRNYGSSIKYKNDLLGYNSRLDELQAIILNI
ECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHH
KLKYLDAMNEHKRNLAKIYLENLKDDFIKPVIDEGTYDVYHIFNVRHTRRDGLRDYLLKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHC
GVKTEIHYPIPPHKQVAMKDVFTYVEGEFAISEEVHRTTLSLPISTFHTKNDIYKVVEIM
CCCEEEECCCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHEECCHHHHHCHHHHHHHHHHH
NRF
HCC
>Mature Secondary Structure
MIEYENLRLANTRFFEEYKTRLSETIQSGWYILGKEVSSFENQFAQYNGNQYCIGVGNGL
CCCCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCEEEEECCCCH
DALILALKALNIEKDSEIIVPSNTYIASILAILHAGLRPILVEPDIRTYNIDPERIEEKI
HHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHCCCCCEEECCCCEEECCCHHHHHHHH
NSRTKGILIVHLYGKPCEMDSILKIKEKNNLFLVEDCAQSHGALYKGKKTGTFGEINGFS
CCCCCCEEEEEEECCCCCCCHHEEEECCCCEEEEEHHHHHCCCEEECCCCCCCCCCCCEE
FYPTKNLGAIGDAGAVVTDNDLYHDEVKKLRNYGSSIKYKNDLLGYNSRLDELQAIILNI
ECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHH
KLKYLDAMNEHKRNLAKIYLENLKDDFIKPVIDEGTYDVYHIFNVRHTRRDGLRDYLLKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHC
GVKTEIHYPIPPHKQVAMKDVFTYVEGEFAISEEVHRTTLSLPISTFHTKNDIYKVVEIM
CCCEEEECCCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHEECCHHHHHCHHHHHHHHHHH
NRF
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2575703 [H]