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The map label for this gene is aroB [H]

Identifier: 116327696

GI number: 116327696

Start: 1090211

End: 1091302

Strand: Direct

Name: aroB [H]

Synonym: LBL_0942

Alternate gene names: 116327696

Gene position: 1090211-1091302 (Clockwise)

Preceding gene: 116327695

Following gene: 116327697

Centisome position: 30.16

GC content: 43.86

Gene sequence:

>1092_bases
ATGAGTCTTATCGAAACCATTTCAGTGAATACGGAACACAAATCTGTTCCGGTTTATCTTTATTCCAATTTTTCCGGTTT
GTCGGAAGAGATTGCGAAACTTCCCGGGATCACTTCCGTTTTCTTAATCACGGAAAGATCGATTCATTCTATTTATTCCA
AATATCTTGAAAAAGAATTATCCTCTCTCGGAATTCCCGTCAAAGGGATCTATATCAAAGGCGGAGAAAAGTCGAAACAC
ATCGATCGAACCGGACATATTTACAACCGCCTCATTGAACACGGGGCGGATCGTATGTCTTTGATTCTTGCATTTGGCGG
CGGGGTCGTGGGAGATTTTGCCGGTTTCATCGCTTCCACTTATCTGAGAGGAATTCGTTTCGTTCAGATTCCGACGACGC
TCCTCGCTTGTGTGGATTCTTCCGTCGGAGGCAAGGTTGCGGTGAACGCCGACTTCGGAAAAAATATGATTGGCTCTTTT
TATCAACCCGAGTTCGTGTTTGCCCCTTTGTTCGTTTTGTCTACTCTACCCGATAGGGAATGGAGATGTGGTCAGGCGGA
AATCATAAAACACGCCCTTCTTTCCGGCGGCGAATACTGGGAAAAAGTCAAGAAACATTCATTCAAAGATTTGAATGTAA
GTTCTCCGATCCTTCCTTACTTAATCGCGGAGTCGGTTCGTTTTAAAGCGAACGTGGTTTCAAACGACGAAAAGGAAACA
GGACTACGAAAAATTCTAAATCTCGGACACACCACCGCTCATGCGATCGAATCGGTCACGAGGTATAAGAAATATTCTCA
CGGAGAGGCGGTTGCGATCGGTCTTGTAACCGCGCTTTTAATCAGCGAACAAAAATCGGGTCTCGATCCGATCACCATAC
AAGAAACGATCGAAACTCTGAAAAATTACGGACTTCCGTTTCAGGTTAAATTAAAATCCAAAGAACTCGCCAAACACATG
CTTCACGATAAGAAAAACTTGGGCGGTTCGATTCGTTTTGTCCTTTTGAAAAAGCCGGGTCTTCCCGTTTTCGATGTTCC
CGTGGAATCCAGAGACATCATATTAACAATTCGTAAACAAAAAGGTCTTTGA

Upstream 100 bases:

>100_bases
TTCGTGAAATGGATCTTAGACCAGACATCAAATTCTTCCTTTTGGAAGGAGATTTTAAATCAGCGCCGTTTATCAAAAGC
ACTTGGGTATCGGAAAAAAA

Downstream 100 bases:

>100_bases
TGTATTTTGTAATTGATTTTTTGAAAAGTATCAACCCGTTCCTTCTTTTGAAGATGACGGATCGAAGTCTTTCCGAAGAG
TTGATTTTGATCGCCTATTT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSLIETISVNTEHKSVPVYLYSNFSGLSEEIAKLPGITSVFLITERSIHSIYSKYLEKELSSLGIPVKGIYIKGGEKSKH
IDRTGHIYNRLIEHGADRMSLILAFGGGVVGDFAGFIASTYLRGIRFVQIPTTLLACVDSSVGGKVAVNADFGKNMIGSF
YQPEFVFAPLFVLSTLPDREWRCGQAEIIKHALLSGGEYWEKVKKHSFKDLNVSSPILPYLIAESVRFKANVVSNDEKET
GLRKILNLGHTTAHAIESVTRYKKYSHGEAVAIGLVTALLISEQKSGLDPITIQETIETLKNYGLPFQVKLKSKELAKHM
LHDKKNLGGSIRFVLLKKPGLPVFDVPVESRDIILTIRKQKGL

Sequences:

>Translated_363_residues
MSLIETISVNTEHKSVPVYLYSNFSGLSEEIAKLPGITSVFLITERSIHSIYSKYLEKELSSLGIPVKGIYIKGGEKSKH
IDRTGHIYNRLIEHGADRMSLILAFGGGVVGDFAGFIASTYLRGIRFVQIPTTLLACVDSSVGGKVAVNADFGKNMIGSF
YQPEFVFAPLFVLSTLPDREWRCGQAEIIKHALLSGGEYWEKVKKHSFKDLNVSSPILPYLIAESVRFKANVVSNDEKET
GLRKILNLGHTTAHAIESVTRYKKYSHGEAVAIGLVTALLISEQKSGLDPITIQETIETLKNYGLPFQVKLKSKELAKHM
LHDKKNLGGSIRFVLLKKPGLPVFDVPVESRDIILTIRKQKGL
>Mature_362_residues
SLIETISVNTEHKSVPVYLYSNFSGLSEEIAKLPGITSVFLITERSIHSIYSKYLEKELSSLGIPVKGIYIKGGEKSKHI
DRTGHIYNRLIEHGADRMSLILAFGGGVVGDFAGFIASTYLRGIRFVQIPTTLLACVDSSVGGKVAVNADFGKNMIGSFY
QPEFVFAPLFVLSTLPDREWRCGQAEIIKHALLSGGEYWEKVKKHSFKDLNVSSPILPYLIAESVRFKANVVSNDEKETG
LRKILNLGHTTAHAIESVTRYKKYSHGEAVAIGLVTALLISEQKSGLDPITIQETIETLKNYGLPFQVKLKSKELAKHML
HDKKNLGGSIRFVLLKKPGLPVFDVPVESRDIILTIRKQKGL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=334, Percent_Identity=38.9221556886228, Blast_Score=222, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6320332, Length=308, Percent_Identity=36.3636363636364, Blast_Score=180, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40186; Mature: 40055

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIETISVNTEHKSVPVYLYSNFSGLSEEIAKLPGITSVFLITERSIHSIYSKYLEKEL
CCCEEEEECCCCCCCEEEEEECCCCCHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHH
SSLGIPVKGIYIKGGEKSKHIDRTGHIYNRLIEHGADRMSLILAFGGGVVGDFAGFIAST
HHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHH
YLRGIRFVQIPTTLLACVDSSVGGKVAVNADFGKNMIGSFYQPEFVFAPLFVLSTLPDRE
HHHCEEEEEHHHHHHHHHCCCCCCEEEEECCCCCHHHCCCCCCHHHHHHHHHHHCCCCCC
WRCGQAEIIKHALLSGGEYWEKVKKHSFKDLNVSSPILPYLIAESVRFKANVVSNDEKET
CCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHEEEEECCCCHHHH
GLRKILNLGHTTAHAIESVTRYKKYSHGEAVAIGLVTALLISEQKSGLDPITIQETIETL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHH
KNYGLPFQVKLKSKELAKHMLHDKKNLGGSIRFVLLKKPGLPVFDVPVESRDIILTIRKQ
HHCCCCEEEEECHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECCCCCCCEEEEEECC
KGL
CCC
>Mature Secondary Structure 
SLIETISVNTEHKSVPVYLYSNFSGLSEEIAKLPGITSVFLITERSIHSIYSKYLEKEL
CCEEEEECCCCCCCEEEEEECCCCCHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHH
SSLGIPVKGIYIKGGEKSKHIDRTGHIYNRLIEHGADRMSLILAFGGGVVGDFAGFIAST
HHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHH
YLRGIRFVQIPTTLLACVDSSVGGKVAVNADFGKNMIGSFYQPEFVFAPLFVLSTLPDRE
HHHCEEEEEHHHHHHHHHCCCCCCEEEEECCCCCHHHCCCCCCHHHHHHHHHHHCCCCCC
WRCGQAEIIKHALLSGGEYWEKVKKHSFKDLNVSSPILPYLIAESVRFKANVVSNDEKET
CCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHEEEEECCCCHHHH
GLRKILNLGHTTAHAIESVTRYKKYSHGEAVAIGLVTALLISEQKSGLDPITIQETIETL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHH
KNYGLPFQVKLKSKELAKHMLHDKKNLGGSIRFVLLKKPGLPVFDVPVESRDIILTIRKQ
HHCCCCEEEEECHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECCCCCCCEEEEEECC
KGL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA