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The map label for this gene is aglR [H]

Identifier: 116248931

GI number: 116248931

Start: 273820

End: 274830

Strand: Direct

Name: aglR [H]

Synonym: pRL120261

Alternate gene names: 116248931

Gene position: 273820-274830 (Clockwise)

Preceding gene: 116248930

Following gene: 116248932

Centisome position: 31.47

GC content: 65.88

Gene sequence:

>1011_bases
TTGGCCAATCTCAAACAGCTCGCGCAATCGCTGGGACTATCGATCACCACGGTGTCGCGTGCGCTCGACGGTTATGCCGA
TGTGTCGGCGGCTACACGCGAAAGAGTTCGTGATGCTGCCGACAAGGTCGGCTACCGGCCGAATGCGTCCGCCCGCCGCC
TGCGCAGGCAGCGCGCCGAGCTGGTCGCCGTCACGCTGCCGAGCGATCCCGGCCATATCGGCCCTCCGCATTTCCTCGAT
ATGCTGTCCGGCTGTGCCGAACATCTTGCCGCTGCCGGCCTCAATCTGGTGATTGCACCGGTGCCGCGCGGCGAGAGCGA
ACTCGACATCTGCCGCCGCTTCGTCGATGGCCGCCGCGTCGACGCCATGCTTCTCGTCCGCACCAAACGGAAGGACGAGC
GCGTCGAATTTCTGCAATCGCGCGGCATTCCCTTCGTCACCAACGGCCGCACGGAAAGCCTGCTGCCCCATCCCTATATC
GACGGCGACGGTTTTGCCGGCTTCCGGGCCGCGACGCTGCGCTTCCATGCTGCCGGCCACCGCCGTATCGGCCACATCGC
CGGCCCGCAGGAATATTATTTCGCACATGACCGCTGCCGTGGCTGGCGGGCGGCGATGGAGGAATGCGGCCTTGCCACCG
ACCTCTGCGCCGAAGGCGCGCCGTTGGAACAGGGCGGTTATCTCGCCGCACTCGAACTTCTGCGCCAACCCTCGCGTCCG
ACCGCACTCGTTTGCGCCACCGACGAAATGGCGATCGGAGCGCTCCGGGCGCTGCGCGAGGTCGATGGCGGCAACCAGAT
CAGCATTGTCGGCCATGACGACCTAGCGATGGGCGCCTTCACAAGCCCGCCGCTGTCCACCATGCGCATGACCGGCGAAA
ACCTCGGCGCGAGCTTCGCCTCGCTGCTGCTGCGCGCAATTGCAGGCGAACCCGCCGAAGAACTCCAGGAGCTTCACGCG
ATCGAATTCGTCGATCGCGACAGCCATCGCCATCCCGCCAAGGCGGCATAG

Upstream 100 bases:

>100_bases
GATAATCGCAGAATTCCTGTGCCCTTCATCAAGCCAAAACGTTTTGGCTTGACTCCCAAAACGTTTTGGAGAATCTTTTT
CTCACTTCGGGAGGAAGATC

Downstream 100 bases:

>100_bases
ACAGCCGTGCATCTCAAACAAAGAACAATGAAGGAGGAGAAGATGAAACATATCATGTCATTTGGAATTCTGGCTTCCAC
CGTGCTGGCCTTCGCCTCGC

Product: putative HTH-type transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MANLKQLAQSLGLSITTVSRALDGYADVSAATRERVRDAADKVGYRPNASARRLRRQRAELVAVTLPSDPGHIGPPHFLD
MLSGCAEHLAAAGLNLVIAPVPRGESELDICRRFVDGRRVDAMLLVRTKRKDERVEFLQSRGIPFVTNGRTESLLPHPYI
DGDGFAGFRAATLRFHAAGHRRIGHIAGPQEYYFAHDRCRGWRAAMEECGLATDLCAEGAPLEQGGYLAALELLRQPSRP
TALVCATDEMAIGALRALREVDGGNQISIVGHDDLAMGAFTSPPLSTMRMTGENLGASFASLLLRAIAGEPAEELQELHA
IEFVDRDSHRHPAKAA

Sequences:

>Translated_336_residues
MANLKQLAQSLGLSITTVSRALDGYADVSAATRERVRDAADKVGYRPNASARRLRRQRAELVAVTLPSDPGHIGPPHFLD
MLSGCAEHLAAAGLNLVIAPVPRGESELDICRRFVDGRRVDAMLLVRTKRKDERVEFLQSRGIPFVTNGRTESLLPHPYI
DGDGFAGFRAATLRFHAAGHRRIGHIAGPQEYYFAHDRCRGWRAAMEECGLATDLCAEGAPLEQGGYLAALELLRQPSRP
TALVCATDEMAIGALRALREVDGGNQISIVGHDDLAMGAFTSPPLSTMRMTGENLGASFASLLLRAIAGEPAEELQELHA
IEFVDRDSHRHPAKAA
>Mature_335_residues
ANLKQLAQSLGLSITTVSRALDGYADVSAATRERVRDAADKVGYRPNASARRLRRQRAELVAVTLPSDPGHIGPPHFLDM
LSGCAEHLAAAGLNLVIAPVPRGESELDICRRFVDGRRVDAMLLVRTKRKDERVEFLQSRGIPFVTNGRTESLLPHPYID
GDGFAGFRAATLRFHAAGHRRIGHIAGPQEYYFAHDRCRGWRAAMEECGLATDLCAEGAPLEQGGYLAALELLRQPSRPT
ALVCATDEMAIGALRALREVDGGNQISIVGHDDLAMGAFTSPPLSTMRMTGENLGASFASLLLRAIAGEPAEELQELHAI
EFVDRDSHRHPAKAA

Specific function: Probable regulatory protein for the binding-protein- dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=335, Percent_Identity=30.4477611940298, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790194, Length=324, Percent_Identity=27.7777777777778, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789202, Length=340, Percent_Identity=28.2352941176471, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787948, Length=320, Percent_Identity=26.875, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789068, Length=296, Percent_Identity=28.3783783783784, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787580, Length=315, Percent_Identity=23.8095238095238, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788474, Length=321, Percent_Identity=30.2180685358255, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786540, Length=337, Percent_Identity=27.299703264095, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI48994940, Length=318, Percent_Identity=25.4716981132075, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787906, Length=326, Percent_Identity=22.6993865030675, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36428; Mature: 36297

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLKQLAQSLGLSITTVSRALDGYADVSAATRERVRDAADKVGYRPNASARRLRRQRAE
CCCHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
LVAVTLPSDPGHIGPPHFLDMLSGCAEHLAAAGLNLVIAPVPRGESELDICRRFVDGRRV
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCC
DAMLLVRTKRKDERVEFLQSRGIPFVTNGRTESLLPHPYIDGDGFAGFRAATLRFHAAGH
CCEEEEHHCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHEEEECCCC
RRIGHIAGPQEYYFAHDRCRGWRAAMEECGLATDLCAEGAPLEQGGYLAALELLRQPSRP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCC
TALVCATDEMAIGALRALREVDGGNQISIVGHDDLAMGAFTSPPLSTMRMTGENLGASFA
CEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCHHHHHHHH
SLLLRAIAGEPAEELQELHAIEFVDRDSHRHPAKAA
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ANLKQLAQSLGLSITTVSRALDGYADVSAATRERVRDAADKVGYRPNASARRLRRQRAE
CCHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
LVAVTLPSDPGHIGPPHFLDMLSGCAEHLAAAGLNLVIAPVPRGESELDICRRFVDGRRV
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCC
DAMLLVRTKRKDERVEFLQSRGIPFVTNGRTESLLPHPYIDGDGFAGFRAATLRFHAAGH
CCEEEEHHCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHEEEECCCC
RRIGHIAGPQEYYFAHDRCRGWRAAMEECGLATDLCAEGAPLEQGGYLAALELLRQPSRP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCC
TALVCATDEMAIGALRALREVDGGNQISIVGHDDLAMGAFTSPPLSTMRMTGENLGASFA
CEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCHHHHHHHH
SLLLRAIAGEPAEELQELHAIEFVDRDSHRHPAKAA
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]