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The map label for this gene is prmA [H]

Identifier: 114799616

GI number: 114799616

Start: 371146

End: 372003

Strand: Direct

Name: prmA [H]

Synonym: HNE_0379

Alternate gene names: 114799616

Gene position: 371146-372003 (Clockwise)

Preceding gene: 114800129

Following gene: 114798858

Centisome position: 10.02

GC content: 65.27

Gene sequence:

>858_bases
ATGTATCAGATCACGGCAAAAGGCCCGCGGGGGCCAGTAGAAACGGCATGGGACGCGCTGGCCTGGGTAGACCCTTCGCC
CGCAGGCGCAGTCGATGCCAAGGAAGACGCGCGCGGCGCGTGGCGGCTCGACGCCTTCTGCGAGACGATGGAAGAGGCAG
AAGAATGCGTCGCCATCATCGAGGAGGCCGCCCCGGAGCTGACGGCGCGGATCGAGGAGATTGTCGAACGCGACTGGGTG
ACCCTGTCGCTTGAAGGGCTGCCGCCGGTAAATGCCGGGCCGTTCGTTGTGGTGGGCAGTCATGCGCTGAAAGCTTCCTC
GCCGGGGAAAATCTCTGTGCTGATCGAAGCGGGGCCGGCTTTCGGTACGGGCCATCATGGCACGACGCTGGGCTGCCTGC
TGGCGCTGGCCGAGGCGCGGCGCCACCGCAAGCCTGGCCGGGTGTTGGATCTGGGAACTGGTTCGGGCGTGCTGGCGATT
GCGGCTTTGAAAGTGGGCGCCGAGATGGCGGTGGGCACCGACATCGACCGGGACTCGGTGTTCGTGGCGCGCGACAATGC
CCGGAAGAACCATGTCAGCCGCTTCTTCGTGCATCATGTGCGCGGGGCCAATAACCCGGCGATCCGGCAGGCGGGGCCGT
ATGATACGGTGTTTGCCAATATCCTGATGAAGCCGCTGATCGGCCTTGCCGGCGAGATTGAGCGGCTGTCGGCGCCGGGC
GCGGTAATCATCCTGTCAGGCTTGCTGCACCATCAGGCCGAGCCCGTGCGCGCCGCGTTTGAAGGCCACGGCATGCTGTT
CCAGAAGCGCATCAAGCGCGACGGATGGTCGAGCCTGGTGTTCCGGAAGAAAGACTGA

Upstream 100 bases:

>100_bases
AGGTTGTGTTAAACTTTGTTAGGCCGTTCGGGCACTGAGTGCCGTATTGGTCTGCCAGACCGCTTCCCATTCGCGGGGCA
GCCTGCTAAGCGCCGCGTCC

Downstream 100 bases:

>100_bases
GGTTTTCGGGAAGATTTACCCTCCGGCCCATCCCTTTGAGGGGATGGGCGAGGAGGGGATCGCACCGGCGCTTTGGGGGA
GGGGACGCATCCGGGCGATC

Product: putative ribosomal protein L11 methyltransferase PrmA

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MYQITAKGPRGPVETAWDALAWVDPSPAGAVDAKEDARGAWRLDAFCETMEEAEECVAIIEEAAPELTARIEEIVERDWV
TLSLEGLPPVNAGPFVVVGSHALKASSPGKISVLIEAGPAFGTGHHGTTLGCLLALAEARRHRKPGRVLDLGTGSGVLAI
AALKVGAEMAVGTDIDRDSVFVARDNARKNHVSRFFVHHVRGANNPAIRQAGPYDTVFANILMKPLIGLAGEIERLSAPG
AVIILSGLLHHQAEPVRAAFEGHGMLFQKRIKRDGWSSLVFRKKD

Sequences:

>Translated_285_residues
MYQITAKGPRGPVETAWDALAWVDPSPAGAVDAKEDARGAWRLDAFCETMEEAEECVAIIEEAAPELTARIEEIVERDWV
TLSLEGLPPVNAGPFVVVGSHALKASSPGKISVLIEAGPAFGTGHHGTTLGCLLALAEARRHRKPGRVLDLGTGSGVLAI
AALKVGAEMAVGTDIDRDSVFVARDNARKNHVSRFFVHHVRGANNPAIRQAGPYDTVFANILMKPLIGLAGEIERLSAPG
AVIILSGLLHHQAEPVRAAFEGHGMLFQKRIKRDGWSSLVFRKKD
>Mature_285_residues
MYQITAKGPRGPVETAWDALAWVDPSPAGAVDAKEDARGAWRLDAFCETMEEAEECVAIIEEAAPELTARIEEIVERDWV
TLSLEGLPPVNAGPFVVVGSHALKASSPGKISVLIEAGPAFGTGHHGTTLGCLLALAEARRHRKPGRVLDLGTGSGVLAI
AALKVGAEMAVGTDIDRDSVFVARDNARKNHVSRFFVHHVRGANNPAIRQAGPYDTVFANILMKPLIGLAGEIERLSAPG
AVIILSGLLHHQAEPVRAAFEGHGMLFQKRIKRDGWSSLVFRKKD

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=237, Percent_Identity=34.1772151898734, Blast_Score=81, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 30523; Mature: 30523

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQITAKGPRGPVETAWDALAWVDPSPAGAVDAKEDARGAWRLDAFCETMEEAEECVAII
CEEEECCCCCCCHHHHHHHHEECCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHH
EEAAPELTARIEEIVERDWVTLSLEGLPPVNAGPFVVVGSHALKASSPGKISVLIEAGPA
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCEECCCCCCEEEEEEECCCC
FGTGHHGTTLGCLLALAEARRHRKPGRVLDLGTGSGVLAIAALKVGAEMAVGTDIDRDSV
CCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCHHEECCCCCCCCE
FVARDNARKNHVSRFFVHHVRGANNPAIRQAGPYDTVFANILMKPLIGLAGEIERLSAPG
EEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCC
AVIILSGLLHHQAEPVRAAFEGHGMLFQKRIKRDGWSSLVFRKKD
HHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCCCCCCCEEECC
>Mature Secondary Structure
MYQITAKGPRGPVETAWDALAWVDPSPAGAVDAKEDARGAWRLDAFCETMEEAEECVAII
CEEEECCCCCCCHHHHHHHHEECCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHH
EEAAPELTARIEEIVERDWVTLSLEGLPPVNAGPFVVVGSHALKASSPGKISVLIEAGPA
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCEECCCCCCEEEEEEECCCC
FGTGHHGTTLGCLLALAEARRHRKPGRVLDLGTGSGVLAIAALKVGAEMAVGTDIDRDSV
CCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCHHEECCCCCCCCE
FVARDNARKNHVSRFFVHHVRGANNPAIRQAGPYDTVFANILMKPLIGLAGEIERLSAPG
EEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCC
AVIILSGLLHHQAEPVRAAFEGHGMLFQKRIKRDGWSSLVFRKKD
HHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]