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The map label for this gene is yfhM [H]

Identifier: 114799595

GI number: 114799595

Start: 2519869

End: 2520831

Strand: Direct

Name: yfhM [H]

Synonym: HNE_2413

Alternate gene names: 114799595

Gene position: 2519869-2520831 (Clockwise)

Preceding gene: 114797339

Following gene: 114797874

Centisome position: 68.01

GC content: 61.27

Gene sequence:

>963_bases
ATGAGTTGGCCGGGCGTTACGCAGCGCCGGGTTGCGACCAACGGCATTGAGCTGAACATTGCCGAGGCGGGCGAAGGCCC
GCTGGTGCTTCTGCTGCATGGCTTTCCGGAATCCTGGTATTCTTGGCGCCATCAGTTCGCGCCTCTGGCAGCGGCGGGCT
ATCATGTCGTCGCGCCGGACATGCGCGGCTATGGCAAGAGCGACAAGCCGCCGGAAATTACCGACTATGTTCAGACAGAA
GTTATTAAGGACGTTATCGGCCTGATCCCGGCGCTGGGCTATGACAATGCCGTTGTGATCGGACATGACTGGGGGGCGCC
GACGGCATGGTCGACCGCGCTGTTCCATCCGGACAAGGTGCGGGCCGTGGGCGGACTTTCCGTGCCGTTCATGCCGCGCT
CGCCCGTTCAGCCGATGCCGATGCTGCGGGAAATTTACAAAGGCCAGTTCTTCTACCAACTCTATTTCCAGGAGCCGGGC
GTCGCCGAGGCCGAATTCGAGAAGGACATGCACACCGCGCTACGCAAGTTCCTGATCATGGCGGCGGGCGAGACAGACCT
GACCACGCTGGCGCCTAAGACGGAAGATGACGACCTTCTCACCAGCCTGCCCTATCCGGAAACGCTGCCGAAATGGCTGA
CGGCCGCCGACCTCGATTTCTATGTGTCGGAGTTCACGGCGTCCGGCATGCGCGGGCCCATCAACTATTACCGCAACCAC
GACCTTCACTGGCAACTGACCGAAGGCGCGCCGATGGAAATCCATCAGCCTGCGATGTTTATTGCCGGCACGGCGGACGG
CGTGGTGATGATGGCGGCGGCCGCCATTGAGGCCATGCCGCATTTCGTCAAGGACCTGCGGATCAACAAGATGATCCCCG
GCATCGGCCACTGGACCCAACAGGAAGCGCCGGAGGCGGTCAACGAGACCATCCTGGAATTCCTTCGCAACATCGACTCC
TAA

Upstream 100 bases:

>100_bases
GCGGCGGCGTCGCCTGGTCGGCGGCTGCGGGCTACAAGGACGACACGCGCGGCGCGATCCTGCCGGGCGAAGCGGCAGCA
ACCCGCCCGCTGGTGGCCGC

Downstream 100 bases:

>100_bases
ACCCTCAGGGGACCACGCATGCGTGAACAAGTAATCGTCATTGGCGCCGGAATCGGTGGGCTCTGCACGGCTTTGATGCT
GGCGCCATCGGGGCGTGACA

Product: putative epoxide hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSWPGVTQRRVATNGIELNIAEAGEGPLVLLLHGFPESWYSWRHQFAPLAAAGYHVVAPDMRGYGKSDKPPEITDYVQTE
VIKDVIGLIPALGYDNAVVIGHDWGAPTAWSTALFHPDKVRAVGGLSVPFMPRSPVQPMPMLREIYKGQFFYQLYFQEPG
VAEAEFEKDMHTALRKFLIMAAGETDLTTLAPKTEDDDLLTSLPYPETLPKWLTAADLDFYVSEFTASGMRGPINYYRNH
DLHWQLTEGAPMEIHQPAMFIAGTADGVVMMAAAAIEAMPHFVKDLRINKMIPGIGHWTQQEAPEAVNETILEFLRNIDS

Sequences:

>Translated_320_residues
MSWPGVTQRRVATNGIELNIAEAGEGPLVLLLHGFPESWYSWRHQFAPLAAAGYHVVAPDMRGYGKSDKPPEITDYVQTE
VIKDVIGLIPALGYDNAVVIGHDWGAPTAWSTALFHPDKVRAVGGLSVPFMPRSPVQPMPMLREIYKGQFFYQLYFQEPG
VAEAEFEKDMHTALRKFLIMAAGETDLTTLAPKTEDDDLLTSLPYPETLPKWLTAADLDFYVSEFTASGMRGPINYYRNH
DLHWQLTEGAPMEIHQPAMFIAGTADGVVMMAAAAIEAMPHFVKDLRINKMIPGIGHWTQQEAPEAVNETILEFLRNIDS
>Mature_319_residues
SWPGVTQRRVATNGIELNIAEAGEGPLVLLLHGFPESWYSWRHQFAPLAAAGYHVVAPDMRGYGKSDKPPEITDYVQTEV
IKDVIGLIPALGYDNAVVIGHDWGAPTAWSTALFHPDKVRAVGGLSVPFMPRSPVQPMPMLREIYKGQFFYQLYFQEPGV
AEAEFEKDMHTALRKFLIMAAGETDLTTLAPKTEDDDLLTSLPYPETLPKWLTAADLDFYVSEFTASGMRGPINYYRNHD
LHWQLTEGAPMEIHQPAMFIAGTADGVVMMAAAAIEAMPHFVKDLRINKMIPGIGHWTQQEAPEAVNETILEFLRNIDS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=304, Percent_Identity=39.1447368421053, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI218777837, Length=320, Percent_Identity=29.6875, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI218777840, Length=316, Percent_Identity=31.0126582278481, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI13376164, Length=316, Percent_Identity=31.0126582278481, Blast_Score=141, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17554012, Length=322, Percent_Identity=31.055900621118, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17562298, Length=317, Percent_Identity=28.0757097791798, Blast_Score=117, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 35655; Mature: 35524

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWPGVTQRRVATNGIELNIAEAGEGPLVLLLHGFPESWYSWRHQFAPLAAAGYHVVAPD
CCCCCCCHHHHCCCCEEEEEEECCCCCEEEEEECCCHHHHHHHHHCCCHHHCCCEEECCC
MRGYGKSDKPPEITDYVQTEVIKDVIGLIPALGYDNAVVIGHDWGAPTAWSTALFHPDKV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHEEECCHHH
RAVGGLSVPFMPRSPVQPMPMLREIYKGQFFYQLYFQEPGVAEAEFEKDMHTALRKFLIM
HHCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
AAGETDLTTLAPKTEDDDLLTSLPYPETLPKWLTAADLDFYVSEFTASGMRGPINYYRNH
CCCCCCCEECCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
DLHWQLTEGAPMEIHQPAMFIAGTADGVVMMAAAAIEAMPHFVKDLRINKMIPGIGHWTQ
CCEEEECCCCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
QEAPEAVNETILEFLRNIDS
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SWPGVTQRRVATNGIELNIAEAGEGPLVLLLHGFPESWYSWRHQFAPLAAAGYHVVAPD
CCCCCCHHHHCCCCEEEEEEECCCCCEEEEEECCCHHHHHHHHHCCCHHHCCCEEECCC
MRGYGKSDKPPEITDYVQTEVIKDVIGLIPALGYDNAVVIGHDWGAPTAWSTALFHPDKV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHEEECCHHH
RAVGGLSVPFMPRSPVQPMPMLREIYKGQFFYQLYFQEPGVAEAEFEKDMHTALRKFLIM
HHCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
AAGETDLTTLAPKTEDDDLLTSLPYPETLPKWLTAADLDFYVSEFTASGMRGPINYYRNH
CCCCCCCEECCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
DLHWQLTEGAPMEIHQPAMFIAGTADGVVMMAAAAIEAMPHFVKDLRINKMIPGIGHWTQ
CCEEEECCCCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
QEAPEAVNETILEFLRNIDS
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]