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The map label for this gene is pcbC [H]

Identifier: 114799572

GI number: 114799572

Start: 2344554

End: 2345501

Strand: Direct

Name: pcbC [H]

Synonym: HNE_2242

Alternate gene names: 114799572

Gene position: 2344554-2345501 (Clockwise)

Preceding gene: 114798196

Following gene: 114797797

Centisome position: 63.28

GC content: 62.87

Gene sequence:

>948_bases
ATGACCCAATATTTCGAACCGATCCCCTACCCGCTCTGGCACACCGACAAGGCAGGCTTTGCCGAAAAGCTCGGAAAGTC
CTTCCGGGAAACCGGCTTTGCCGTCATCACCGGCCATCCGATCCAGCAGCCCGTGATCGATGACAACCTTGCGGCCACCA
AGGCGTTCTTCGCCCTGCCTGAAGCGGCCAAGGAAACCTACCATGACGCGCCCGGCGGCCGTCAGCGGGGGTACACGCCC
TTCGGAACAGAAAACGCCAAGGGTCAGGCGCAGGCAGACCTCAAGGAATTCTGGCACACCGGGCGCGACCTGCCGCCAGG
TTCCCCCTACCGCGCCACAATGAAAGACACGCCCAGCGTCTCTGAAGTGGCCGATTTCGACCGCGCCACCCATACCCTCT
ACACGGCGCTGGATGATTTCGGCGCTGACCTGCTCAAAGGTGTGGCGCTGCATCTGAACCTTCCCGAGGACTGGTTTGCC
GACAAGGTGAACTTCGGCAACTCGATCCTGCGCCTTCTGCATTATCCGCCGCAGATGAACCCGCCACCGGAAGGCTCGGT
CCGCGCCGGCGCGCATGAAGACATCAACGTCATCACCCTGCTGCTGGGCGCAGAGGAAGCCGGTCTCGAAGTGAAACACC
GCTCGGGCAAATGGCTGGCGGTGAACCCGCCGCCGGGCGCCCTGGTCATAAATTGCGGCGACATGCTCCAGCGTTATACC
GGCGGCGTGCTGCCTTCGACGACGCACCGCGTCGTCAATCCCGCGCCGGAACGCGCCCGCTTCCCGCGCTATTCGACGCC
CTTCTTCCTTCACTTCAATCAGGATTTCATGATTGAAGCCCTGCCCGGCTGCCTCGCCGAAGGCGGCAAGGCCCAGCCAC
CGATCACAGCGCAGGACTTCCTGATGGAGCGCCTGCGCGAGATCGGGCTGGTCAAAGAGCGCAGTTAA

Upstream 100 bases:

>100_bases
GGCCCCGCGTGCCGCCTTGCCCATATAGACCATCAGCTTCCTGCTTTCCGCGTCAGGCCGCCCCCTATCGGGCCCCTGCC
ACTTCTGGCAAAATATCCTC

Downstream 100 bases:

>100_bases
CCCTGCTCTACCTCTCGTTACCGGCCATGCCCGCTGGCACGGAAGTTGACTGTCTCCAGATGGCCTGAGCCAATCTGGGA
GCCACGATCATGCCAGCCAT

Product: 2OG-Fe(II) oxygenase family oxidoreductase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTQYFEPIPYPLWHTDKAGFAEKLGKSFRETGFAVITGHPIQQPVIDDNLAATKAFFALPEAAKETYHDAPGGRQRGYTP
FGTENAKGQAQADLKEFWHTGRDLPPGSPYRATMKDTPSVSEVADFDRATHTLYTALDDFGADLLKGVALHLNLPEDWFA
DKVNFGNSILRLLHYPPQMNPPPEGSVRAGAHEDINVITLLLGAEEAGLEVKHRSGKWLAVNPPPGALVINCGDMLQRYT
GGVLPSTTHRVVNPAPERARFPRYSTPFFLHFNQDFMIEALPGCLAEGGKAQPPITAQDFLMERLREIGLVKERS

Sequences:

>Translated_315_residues
MTQYFEPIPYPLWHTDKAGFAEKLGKSFRETGFAVITGHPIQQPVIDDNLAATKAFFALPEAAKETYHDAPGGRQRGYTP
FGTENAKGQAQADLKEFWHTGRDLPPGSPYRATMKDTPSVSEVADFDRATHTLYTALDDFGADLLKGVALHLNLPEDWFA
DKVNFGNSILRLLHYPPQMNPPPEGSVRAGAHEDINVITLLLGAEEAGLEVKHRSGKWLAVNPPPGALVINCGDMLQRYT
GGVLPSTTHRVVNPAPERARFPRYSTPFFLHFNQDFMIEALPGCLAEGGKAQPPITAQDFLMERLREIGLVKERS
>Mature_314_residues
TQYFEPIPYPLWHTDKAGFAEKLGKSFRETGFAVITGHPIQQPVIDDNLAATKAFFALPEAAKETYHDAPGGRQRGYTPF
GTENAKGQAQADLKEFWHTGRDLPPGSPYRATMKDTPSVSEVADFDRATHTLYTALDDFGADLLKGVALHLNLPEDWFAD
KVNFGNSILRLLHYPPQMNPPPEGSVRAGAHEDINVITLLLGAEEAGLEVKHRSGKWLAVNPPPGALVINCGDMLQRYTG
GVLPSTTHRVVNPAPERARFPRYSTPFFLHFNQDFMIEALPGCLAEGGKAQPPITAQDFLMERLREIGLVKERS

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI85816264, Length=263, Percent_Identity=30.4182509505703, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28572124, Length=284, Percent_Identity=29.2253521126761, Blast_Score=95, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 34802; Mature: 34671

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQYFEPIPYPLWHTDKAGFAEKLGKSFRETGFAVITGHPIQQPVIDDNLAATKAFFALP
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHCC
EAAKETYHDAPGGRQRGYTPFGTENAKGQAQADLKEFWHTGRDLPPGSPYRATMKDTPSV
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCH
SEVADFDRATHTLYTALDDFGADLLKGVALHLNLPEDWFADKVNFGNSILRLLHYPPQMN
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCC
PPPEGSVRAGAHEDINVITLLLGAEEAGLEVKHRSGKWLAVNPPPGALVINCGDMLQRYT
CCCCCCCCCCCCCCCEEEEEEECCHHHCCEEEECCCCEEEECCCCCEEEECHHHHHHHHH
GGVLPSTTHRVVNPAPERARFPRYSTPFFLHFNQDFMIEALPGCLAEGGKAQPPITAQDF
CCCCCCCCHHHCCCCHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHH
LMERLREIGLVKERS
HHHHHHHCCCCCCCC
>Mature Secondary Structure 
TQYFEPIPYPLWHTDKAGFAEKLGKSFRETGFAVITGHPIQQPVIDDNLAATKAFFALP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHCC
EAAKETYHDAPGGRQRGYTPFGTENAKGQAQADLKEFWHTGRDLPPGSPYRATMKDTPSV
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCH
SEVADFDRATHTLYTALDDFGADLLKGVALHLNLPEDWFADKVNFGNSILRLLHYPPQMN
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCC
PPPEGSVRAGAHEDINVITLLLGAEEAGLEVKHRSGKWLAVNPPPGALVINCGDMLQRYT
CCCCCCCCCCCCCCCEEEEEEECCHHHCCEEEECCCCEEEECCCCCEEEECHHHHHHHHH
GGVLPSTTHRVVNPAPERARFPRYSTPFFLHFNQDFMIEALPGCLAEGGKAQPPITAQDF
CCCCCCCCHHHCCCCHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHH
LMERLREIGLVKERS
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1901702 [H]