Click here to switch to the map view.

The map label for this gene is map1 [H]

Identifier: 114798256

GI number: 114798256

Start: 967971

End: 968792

Strand: Reverse

Name: map1 [H]

Synonym: HNE_0953

Alternate gene names: 114798256

Gene position: 968792-967971 (Counterclockwise)

Preceding gene: 114797833

Following gene: 114799369

Centisome position: 26.15

GC content: 62.65

Gene sequence:

>822_bases
ATGAACGACACAAACCTCCTCCTGCCCATGCGCACCGGCGAAATCCGCATTCACGACGCCGAAGGCTTCGAAGGCATGCG
CCGCGCTGGCCGCCTTGTCGCCGAATGTCTCGACATGCTGGTGCCGGAAGTGAAACCCGGTGTCACAACCGAGCATCTGG
ACAATCTGGTCCGCGAGTTCGTGCAGGATCATGGCGCCGTATCCGCCACCATCGGCTATCGCGGCTACCGCCACGCATCC
TGTATCTCGGTGAATCACGTGATCTGCCACGGCATTCCGGGTGGCAAGGCCCTCAAGGAAGGCGACATCGCCAATATCGA
TGTGACGCTGATCATCGACGGCTGGCATGGCGATCATAGCCGGATGTATGGCGTGGGCGAGGTGAAGCGCAAAGCCGAAC
GCCTGATGGAAGTGACCTATGAGGCCATGATGGCCGGCATAGCGGCGGTGAAGCCGGGCGGACGATTTGGCGACATCGGC
GGCGCGATCAGCGAGATTGCGCGCCTCAACCGCTATTCGGTGGTTGATGATTTCTGCGGGCACGGGCTCGGGCGCCTCTT
CCATGACGAGCCCAATGTGGTTCACTCTGCCAAGGCAGGCACCGGGCCGGAGCTGAAGCCCGGCATGTTCTTCACCATCG
AACCGATGCTGAACCTCGGCCGCCGCGACGCCGCGATCCTGCCAGATGGCTGGACCGCCGTGACACGGGACCGCCAGCTC
TCGGCGCAGTTCGAGCATTCGGTGGGCGTGACCGAGACGGGCGTGGAGATTTTCTCCGCCTCGCCCAAGGGCTGGCATGA
GCCTTACAAGGTGAAGCTCTGA

Upstream 100 bases:

>100_bases
TTCCGTGCTGCGCCTTTAACTGGCAGCGCCTGCGATCTTCGGCAAGGCAGCAGTTGATTAGGTGTGGAAAACCGGCCCTT
CCCCTGCCATATTGGGGGAC

Downstream 100 bases:

>100_bases
GCTCTTGTCTTCCCGGCGAAAGCCGGGACCCAGACTTTGCTTTGCAACCGCTTGACGAACGCGAATGTTCGTGGAATGTT
CCGGCATGCTTTCGGCGCCG

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MNDTNLLLPMRTGEIRIHDAEGFEGMRRAGRLVAECLDMLVPEVKPGVTTEHLDNLVREFVQDHGAVSATIGYRGYRHAS
CISVNHVICHGIPGGKALKEGDIANIDVTLIIDGWHGDHSRMYGVGEVKRKAERLMEVTYEAMMAGIAAVKPGGRFGDIG
GAISEIARLNRYSVVDDFCGHGLGRLFHDEPNVVHSAKAGTGPELKPGMFFTIEPMLNLGRRDAAILPDGWTAVTRDRQL
SAQFEHSVGVTETGVEIFSASPKGWHEPYKVKL

Sequences:

>Translated_273_residues
MNDTNLLLPMRTGEIRIHDAEGFEGMRRAGRLVAECLDMLVPEVKPGVTTEHLDNLVREFVQDHGAVSATIGYRGYRHAS
CISVNHVICHGIPGGKALKEGDIANIDVTLIIDGWHGDHSRMYGVGEVKRKAERLMEVTYEAMMAGIAAVKPGGRFGDIG
GAISEIARLNRYSVVDDFCGHGLGRLFHDEPNVVHSAKAGTGPELKPGMFFTIEPMLNLGRRDAAILPDGWTAVTRDRQL
SAQFEHSVGVTETGVEIFSASPKGWHEPYKVKL
>Mature_273_residues
MNDTNLLLPMRTGEIRIHDAEGFEGMRRAGRLVAECLDMLVPEVKPGVTTEHLDNLVREFVQDHGAVSATIGYRGYRHAS
CISVNHVICHGIPGGKALKEGDIANIDVTLIIDGWHGDHSRMYGVGEVKRKAERLMEVTYEAMMAGIAAVKPGGRFGDIG
GAISEIARLNRYSVVDDFCGHGLGRLFHDEPNVVHSAKAGTGPELKPGMFFTIEPMLNLGRRDAAILPDGWTAVTRDRQL
SAQFEHSVGVTETGVEIFSASPKGWHEPYKVKL

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=248, Percent_Identity=45.9677419354839, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI40385867, Length=259, Percent_Identity=37.8378378378378, Blast_Score=186, Evalue=3e-47,
Organism=Escherichia coli, GI1786364, Length=247, Percent_Identity=49.7975708502024, Blast_Score=246, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI71996291, Length=246, Percent_Identity=43.9024390243902, Blast_Score=207, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6323273, Length=254, Percent_Identity=42.9133858267717, Blast_Score=213, Evalue=2e-56,
Organism=Drosophila melanogaster, GI21355531, Length=260, Percent_Identity=43.0769230769231, Blast_Score=218, Evalue=3e-57,
Organism=Drosophila melanogaster, GI24583427, Length=247, Percent_Identity=37.6518218623482, Blast_Score=178, Evalue=4e-45,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29838; Mature: 29838

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTNLLLPMRTGEIRIHDAEGFEGMRRAGRLVAECLDMLVPEVKPGVTTEHLDNLVREF
CCCCCEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
VQDHGAVSATIGYRGYRHASCISVNHVICHGIPGGKALKEGDIANIDVTLIIDGWHGDHS
HHHCCCEEEEECCCCCCCCCEEEECEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCH
RMYGVGEVKRKAERLMEVTYEAMMAGIAAVKPGGRFGDIGGAISEIARLNRYSVVDDFCG
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
HGLGRLFHDEPNVVHSAKAGTGPELKPGMFFTIEPMLNLGRRDAAILPDGWTAVTRDRQL
CCHHHHCCCCCCEEECCCCCCCCCCCCCEEEEECHHHCCCCCCCEECCCCCEECCCCCHH
SAQFEHSVGVTETGVEIFSASPKGWHEPYKVKL
HHHHHHCCCCCCCCCCEEECCCCCCCCCEEECC
>Mature Secondary Structure
MNDTNLLLPMRTGEIRIHDAEGFEGMRRAGRLVAECLDMLVPEVKPGVTTEHLDNLVREF
CCCCCEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
VQDHGAVSATIGYRGYRHASCISVNHVICHGIPGGKALKEGDIANIDVTLIIDGWHGDHS
HHHCCCEEEEECCCCCCCCCEEEECEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCH
RMYGVGEVKRKAERLMEVTYEAMMAGIAAVKPGGRFGDIGGAISEIARLNRYSVVDDFCG
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
HGLGRLFHDEPNVVHSAKAGTGPELKPGMFFTIEPMLNLGRRDAAILPDGWTAVTRDRQL
CCHHHHCCCCCCEEECCCCCCCCCCCCCEEEEECHHHCCCCCCCEECCCCCEECCCCCHH
SAQFEHSVGVTETGVEIFSASPKGWHEPYKVKL
HHHHHHCCCCCCCCCCEEECCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]