Click here to switch to the map view.

The map label for this gene is iap [C]

Identifier: 114798019

GI number: 114798019

Start: 2404423

End: 2406087

Strand: Direct

Name: iap [C]

Synonym: HNE_2307

Alternate gene names: 114798019

Gene position: 2404423-2406087 (Clockwise)

Preceding gene: 114797263

Following gene: 114799617

Centisome position: 64.9

GC content: 64.26

Gene sequence:

>1665_bases
ATGCGACAGTTTTCTGGCAAAGCGCTTCTTGCGTCTGCTATCATTCTTGGCGCCTGCGGAGCCCCGCAACCCGCCGCCCC
ACCGGCTCCGCCCGCGCCCACAGAGCTTCCCGCCGCCAGCCCCGACGCCATCCGCGCCGACATGGACTTCCTCGCCTCCG
ACGATCTGGAAGGCCGCGAAGCAGGTACGCCCGGCTTTGATCTGGCGGCTGATTATGTCGCCGCCGAATTCGCCGAAATC
GGCCTCGCCCCCGGCGGCGACGCGGGCACCTATTTCCAGACCATCTCCTTCCTGCGCTCGGTTCGCGCGCCCGAAGGCCG
GCTGATGGAAGTCACCAACACCGAAACCGGCGCCGCTGTTCCGTTCACGGAAAATGTGGACTACGCGATGGGCAACTCTC
TCTCCGCTCCGAATGTTGATGTCACCGGCGAGGCCGTCTTCGTCGGCTTCGGTATCGTCGCGCCGGATCTCGGCCGCGAT
GATTTCGAAGGCCTTGATCTGAGCGGCAAAGTCGCCGTCATGCTTGCGGGCACGCCCAAAGGCATCCAGACCGAGGAGCG
CGCCTATTACGGCACCCGCAAATACGCCAACGCGTCAGACCGCGGCGCCATCGCCGTCGTCAGCCTGGAAACCCCCACCT
CGCGCGGCGTCTATCCCTTCGAACGCCTGATCCGCGAAGGCCGTCTCGACGGCGCAAGCCTCACCTGGCTCGGCCCGGAC
GGCGCCCCCTTCAGCCGCGCGCCCAATGTACAGAGCGGCGCCAGCGTCCCGATGGAAAGCGCCGCCAAACTCTTTGAAGG
CACAGAGGGTAACTGGACGGACATCGTCGCCGCCGCCGAAGCCGAAGGCGGCAACGTCAAAGGCTTCGCCCTGCCGTACA
CCATCCACCTCACCCAGGCCTCCACCCACGATCAGGTTCAGTCCGCCAACGTCATCGGCATGATCGAGGGCACAGACCCC
GTCCTCAAGAACGAAGTCATCGTCCTGACGGCCCACCTCGATCATATCGGCATTACAAAGAGCATCGAAGGCGACCAGAT
CAACAATGGCGCGCTCGACAATGCCAGCGGCATCGCCACCCTGCTGGAAGCTGCCCGCATGCTGAAGGCCGGCCCGCCGA
TGAAGCGCTCGGTCATGTTCATTGCCCTGACGGCCGAAGAAAAAGGCCTCCTCGGCGCGCAATACTTCGCCGAGAACCCG
ACCGTTCCGAAGGAAAACCTCGTCGCCAACGTCAATCTCGACATGCCGATCCTGACCTATCCCTTCACAGATCTCGTCGT
GTTCGGCGGCTCGCGCTCGACCATCATCGAGGAAGTGGAAAAGGCCGCCGCCGAGATGGACATCACCCTCAGCCCGGACC
CGGTGCCCGATCAGGGCCTGTTCACCCGCTCGGACCATTTCCGCTTCGTTGAAGCCGGCATCCCCTCGGTCTACCTGATC
CCCGGCTGGGAAAATGGCGGCGCCGAGGAATTTGCCCGTCATATGACCAGCAACTACCACCGCCCGTCGGACGACATGAC
CAATTCCATCGACTTTGACGCCGCCGCCCGCTTTGCCGCCATCAAGGCCCGCATCGCGCTCGCCCTGGCGAACGCCGATG
AACGCCCGCTCTGGCGGAAGGATGACTTCTTCGCCCGCCAGTTCGATGGCCCGATGGAGCCCTGA

Upstream 100 bases:

>100_bases
ATCTCACCCATCCCATGAACTACTGGATGCGCGAATTCTGAGTAGACAAGCGCAACAAAATGCCCTTCGGATGCGGGCAT
TGCAGAAGGAAAGACCTATA

Downstream 100 bases:

>100_bases
AAATGCGCCCGCCCGGCCTCCAGATCAGGAGGCTGGGCGGCCTACTCCCCGGAAATCTCAGCGAAACACGGCCCCTCTCG
TTAGGTCAGTCGTGGACAGG

Product: M20/M25/M40 family peptidase

Products: NA

Alternate protein names: Aminopeptidase; Peptidase; M28 Family Peptidase; Peptidase Family M; Glutamate Carboxypeptidase II; M20/M25/M40 Family Peptidase; Aminopeptidase Family; M28 Family Aminopeptidase; Peptidase Family Protein; M23B Family Peptidase; LB Protein; WD40-Like Beta Propeller; PDZ Domain-Containing Protein

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MRQFSGKALLASAIILGACGAPQPAAPPAPPAPTELPAASPDAIRADMDFLASDDLEGREAGTPGFDLAADYVAAEFAEI
GLAPGGDAGTYFQTISFLRSVRAPEGRLMEVTNTETGAAVPFTENVDYAMGNSLSAPNVDVTGEAVFVGFGIVAPDLGRD
DFEGLDLSGKVAVMLAGTPKGIQTEERAYYGTRKYANASDRGAIAVVSLETPTSRGVYPFERLIREGRLDGASLTWLGPD
GAPFSRAPNVQSGASVPMESAAKLFEGTEGNWTDIVAAAEAEGGNVKGFALPYTIHLTQASTHDQVQSANVIGMIEGTDP
VLKNEVIVLTAHLDHIGITKSIEGDQINNGALDNASGIATLLEAARMLKAGPPMKRSVMFIALTAEEKGLLGAQYFAENP
TVPKENLVANVNLDMPILTYPFTDLVVFGGSRSTIIEEVEKAAAEMDITLSPDPVPDQGLFTRSDHFRFVEAGIPSVYLI
PGWENGGAEEFARHMTSNYHRPSDDMTNSIDFDAAARFAAIKARIALALANADERPLWRKDDFFARQFDGPMEP

Sequences:

>Translated_554_residues
MRQFSGKALLASAIILGACGAPQPAAPPAPPAPTELPAASPDAIRADMDFLASDDLEGREAGTPGFDLAADYVAAEFAEI
GLAPGGDAGTYFQTISFLRSVRAPEGRLMEVTNTETGAAVPFTENVDYAMGNSLSAPNVDVTGEAVFVGFGIVAPDLGRD
DFEGLDLSGKVAVMLAGTPKGIQTEERAYYGTRKYANASDRGAIAVVSLETPTSRGVYPFERLIREGRLDGASLTWLGPD
GAPFSRAPNVQSGASVPMESAAKLFEGTEGNWTDIVAAAEAEGGNVKGFALPYTIHLTQASTHDQVQSANVIGMIEGTDP
VLKNEVIVLTAHLDHIGITKSIEGDQINNGALDNASGIATLLEAARMLKAGPPMKRSVMFIALTAEEKGLLGAQYFAENP
TVPKENLVANVNLDMPILTYPFTDLVVFGGSRSTIIEEVEKAAAEMDITLSPDPVPDQGLFTRSDHFRFVEAGIPSVYLI
PGWENGGAEEFARHMTSNYHRPSDDMTNSIDFDAAARFAAIKARIALALANADERPLWRKDDFFARQFDGPMEP
>Mature_554_residues
MRQFSGKALLASAIILGACGAPQPAAPPAPPAPTELPAASPDAIRADMDFLASDDLEGREAGTPGFDLAADYVAAEFAEI
GLAPGGDAGTYFQTISFLRSVRAPEGRLMEVTNTETGAAVPFTENVDYAMGNSLSAPNVDVTGEAVFVGFGIVAPDLGRD
DFEGLDLSGKVAVMLAGTPKGIQTEERAYYGTRKYANASDRGAIAVVSLETPTSRGVYPFERLIREGRLDGASLTWLGPD
GAPFSRAPNVQSGASVPMESAAKLFEGTEGNWTDIVAAAEAEGGNVKGFALPYTIHLTQASTHDQVQSANVIGMIEGTDP
VLKNEVIVLTAHLDHIGITKSIEGDQINNGALDNASGIATLLEAARMLKAGPPMKRSVMFIALTAEEKGLLGAQYFAENP
TVPKENLVANVNLDMPILTYPFTDLVVFGGSRSTIIEEVEKAAAEMDITLSPDPVPDQGLFTRSDHFRFVEAGIPSVYLI
PGWENGGAEEFARHMTSNYHRPSDDMTNSIDFDAAARFAAIKARIALALANADERPLWRKDDFFARQFDGPMEP

Specific function: This Protein, Presumably An Aminopeptidase, Mediates The Conversion Of E.Coli Alkaline Phosphatase Isozyme 1, To Isozymes 2 And 3 By Removing, One By One, The Two Amino-Terminal Arginine Residues. [C]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.4.11.- [C]

Molecular weight: Translated: 58802; Mature: 58802

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQFSGKALLASAIILGACGAPQPAAPPAPPAPTELPAASPDAIRADMDFLASDDLEGRE
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
AGTPGFDLAADYVAAEFAEIGLAPGGDAGTYFQTISFLRSVRAPEGRLMEVTNTETGAAV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
PFTENVDYAMGNSLSAPNVDVTGEAVFVGFGIVAPDLGRDDFEGLDLSGKVAVMLAGTPK
CCCCCCCHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCC
GIQTEERAYYGTRKYANASDRGAIAVVSLETPTSRGVYPFERLIREGRLDGASLTWLGPD
CCCCHHHHHCCCHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEECCC
GAPFSRAPNVQSGASVPMESAAKLFEGTEGNWTDIVAAAEAEGGNVKGFALPYTIHLTQA
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECC
STHDQVQSANVIGMIEGTDPVLKNEVIVLTAHLDHIGITKSIEGDQINNGALDNASGIAT
CCHHHHHCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHH
LLEAARMLKAGPPMKRSVMFIALTAEEKGLLGAQYFAENPTVPKENLVANVNLDMPILTY
HHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEHHHHCCCCCCCHHHEEEEECCCCCEEEC
PFTDLVVFGGSRSTIIEEVEKAAAEMDITLSPDPVPDQGLFTRSDHFRFVEAGIPSVYLI
CCCCEEEECCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCEECCCCCEEEECCCCEEEEE
PGWENGGAEEFARHMTSNYHRPSDDMTNSIDFDAAARFAAIKARIALALANADERPLWRK
ECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCCCCC
DDFFARQFDGPMEP
CCHHHHHCCCCCCC
>Mature Secondary Structure
MRQFSGKALLASAIILGACGAPQPAAPPAPPAPTELPAASPDAIRADMDFLASDDLEGRE
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
AGTPGFDLAADYVAAEFAEIGLAPGGDAGTYFQTISFLRSVRAPEGRLMEVTNTETGAAV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
PFTENVDYAMGNSLSAPNVDVTGEAVFVGFGIVAPDLGRDDFEGLDLSGKVAVMLAGTPK
CCCCCCCHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCC
GIQTEERAYYGTRKYANASDRGAIAVVSLETPTSRGVYPFERLIREGRLDGASLTWLGPD
CCCCHHHHHCCCHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEECCC
GAPFSRAPNVQSGASVPMESAAKLFEGTEGNWTDIVAAAEAEGGNVKGFALPYTIHLTQA
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECC
STHDQVQSANVIGMIEGTDPVLKNEVIVLTAHLDHIGITKSIEGDQINNGALDNASGIAT
CCHHHHHCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHH
LLEAARMLKAGPPMKRSVMFIALTAEEKGLLGAQYFAENPTVPKENLVANVNLDMPILTY
HHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEHHHHCCCCCCCHHHEEEEECCCCCEEEC
PFTDLVVFGGSRSTIIEEVEKAAAEMDITLSPDPVPDQGLFTRSDHFRFVEAGIPSVYLI
CCCCEEEECCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCEECCCCCEEEECCCCEEEEE
PGWENGGAEEFARHMTSNYHRPSDDMTNSIDFDAAARFAAIKARIALALANADERPLWRK
ECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCCCCC
DDFFARQFDGPMEP
CCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Aminopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA