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The map label for this gene is yfdE [H]

Identifier: 114797996

GI number: 114797996

Start: 1085580

End: 1086785

Strand: Reverse

Name: yfdE [H]

Synonym: HNE_1079

Alternate gene names: 114797996

Gene position: 1086785-1085580 (Counterclockwise)

Preceding gene: 114797814

Following gene: 114799641

Centisome position: 29.33

GC content: 64.01

Gene sequence:

>1206_bases
ATGAGTGAGACCGGCGGACCGCTGAAAGGCCTGCGCGTGCTGGAATTCACCCATATGGTGATGGGCCCTGCGGCAGGCCT
GGTCCTCGCCGATCTCGGCGCAGAGGTCATCAAGGTCGAGCCCATCGGCGGCGACAAGACCCGCCGTCTCAAAGGCTCGG
GTGCGGGTTATTTCCCGATGTATAACCGCAACAAGAAAAGCCTCGCGGTTGATCTCAAATCCGAGGAGGGCAAAGCCATC
GCCCTCGCCCTCGCCGATCAGGCAGACATTTTTATCGAAAACTTCCGCCCCGGCGCGCTCGATGCGCTCGGCTTTGGCTA
TGAGGCCCTCGCCGCCCGCAATCCCCGGCTCATCTACTGTTCTGAAAAAGGGTTCCTTGACGGGCCTTATGCCCACCGTA
CCGCGCTGGACGAAGTTGCCCAGATGATGGGCGGCCTTGCCTACATGACCGGCCCGCCCGGCCGGCCCCTGCGCGCCGGC
GCCTCGGTGATTGACGTCACCGGCGGCATGTTCGGCGCCATCGGCGTGCTCGCCGCCCTCAATGAACGCCAGACCACCGG
CAAGGGCCGCCACGTCACCGCGTCCCTGTTTGAAACCACCGTCTTCCTCGTTGGCCAGCATATTGCCCAATACGCCGTCA
CCGGCTCGCCTGCTGCGCCGATGCCCACGCGCGTCTCTGCCTGGGCGGTCTATGACGTGTTTGATGCAAAGGATGACGAG
AAAGTCTTCGTCGGCGTTGTCTCAGATAGTCAGTGGACGGCCTTCTGCAAGGCGTTTGACCTGGCAGACTGGGCCGCAGA
CGCCAGCCTCGCCGGCAACAACGACCGTGTCGCCCGCCGCGAGGAAATTCTCCCGCGCCTGCGCGCCCTGTTCGCGGGCT
ATTCGAAACAGGACCTGATGGACAAGCTCGAAAAGATCGGCCTGCCCTTCGCGCCCATTCAGCGCCCGGAAGATCTGCTC
GACGATCCCCACCTCCTCGCCAGCGGCGGCCTGCTGGATATGGAACTGCCTGAAGGCGGCGCCGTGTCGCTGCCCGCGTT
GCCCATCACGCTGGACGATCACCGCCCTGGCCTGATGCTTGACCCCCCGCGCATCGGCGCCCATTCGGTGGAAATCCTGA
AATCCCTCGGCCACGCGCAGGACCAGATCGACAGTCTCATCAGCCGCGGCCTTGTCGAAGTCAGCGAAGCTCAGCCAGCG
GAATAA

Upstream 100 bases:

>100_bases
GATTGTTATATCAAAGAATGTATGCCCTAACTTGAAAAGATATATCATTTGAGCAAGTAATGGCAATCATCGCGGGCAGG
AACTTCAGGGAGTATCGAGT

Downstream 100 bases:

>100_bases
ACCCAGGGGCGCGCCCTGGCGTCCGCTTCCTGAAACGCACTGATGGAAGGCGCCTGCAACAGCGTCAGCCCGATCGGGTC
GAGCCCCTCCAGCAGCAACC

Product: L-carnitine dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MSETGGPLKGLRVLEFTHMVMGPAAGLVLADLGAEVIKVEPIGGDKTRRLKGSGAGYFPMYNRNKKSLAVDLKSEEGKAI
ALALADQADIFIENFRPGALDALGFGYEALAARNPRLIYCSEKGFLDGPYAHRTALDEVAQMMGGLAYMTGPPGRPLRAG
ASVIDVTGGMFGAIGVLAALNERQTTGKGRHVTASLFETTVFLVGQHIAQYAVTGSPAAPMPTRVSAWAVYDVFDAKDDE
KVFVGVVSDSQWTAFCKAFDLADWAADASLAGNNDRVARREEILPRLRALFAGYSKQDLMDKLEKIGLPFAPIQRPEDLL
DDPHLLASGGLLDMELPEGGAVSLPALPITLDDHRPGLMLDPPRIGAHSVEILKSLGHAQDQIDSLISRGLVEVSEAQPA
E

Sequences:

>Translated_401_residues
MSETGGPLKGLRVLEFTHMVMGPAAGLVLADLGAEVIKVEPIGGDKTRRLKGSGAGYFPMYNRNKKSLAVDLKSEEGKAI
ALALADQADIFIENFRPGALDALGFGYEALAARNPRLIYCSEKGFLDGPYAHRTALDEVAQMMGGLAYMTGPPGRPLRAG
ASVIDVTGGMFGAIGVLAALNERQTTGKGRHVTASLFETTVFLVGQHIAQYAVTGSPAAPMPTRVSAWAVYDVFDAKDDE
KVFVGVVSDSQWTAFCKAFDLADWAADASLAGNNDRVARREEILPRLRALFAGYSKQDLMDKLEKIGLPFAPIQRPEDLL
DDPHLLASGGLLDMELPEGGAVSLPALPITLDDHRPGLMLDPPRIGAHSVEILKSLGHAQDQIDSLISRGLVEVSEAQPA
E
>Mature_400_residues
SETGGPLKGLRVLEFTHMVMGPAAGLVLADLGAEVIKVEPIGGDKTRRLKGSGAGYFPMYNRNKKSLAVDLKSEEGKAIA
LALADQADIFIENFRPGALDALGFGYEALAARNPRLIYCSEKGFLDGPYAHRTALDEVAQMMGGLAYMTGPPGRPLRAGA
SVIDVTGGMFGAIGVLAALNERQTTGKGRHVTASLFETTVFLVGQHIAQYAVTGSPAAPMPTRVSAWAVYDVFDAKDDEK
VFVGVVSDSQWTAFCKAFDLADWAADASLAGNNDRVARREEILPRLRALFAGYSKQDLMDKLEKIGLPFAPIQRPEDLLD
DPHLLASGGLLDMELPEGGAVSLPALPITLDDHRPGLMLDPPRIGAHSVEILKSLGHAQDQIDSLISRGLVEVSEAQPAE

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=400, Percent_Identity=33, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI300863124, Length=426, Percent_Identity=30.9859154929577, Blast_Score=205, Evalue=6e-53,
Organism=Homo sapiens, GI300863126, Length=399, Percent_Identity=31.077694235589, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI13376042, Length=426, Percent_Identity=27.2300469483568, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI266456254, Length=400, Percent_Identity=25.75, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI42794625, Length=401, Percent_Identity=25.4364089775561, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI266458393, Length=201, Percent_Identity=32.3383084577114, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI266458397, Length=201, Percent_Identity=32.3383084577114, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI42822893, Length=118, Percent_Identity=38.135593220339, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI266458395, Length=120, Percent_Identity=36.6666666666667, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87082093, Length=356, Percent_Identity=31.7415730337079, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1788717, Length=409, Percent_Identity=30.8068459657702, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1786222, Length=404, Percent_Identity=23.5148514851485, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32564160, Length=248, Percent_Identity=27.0161290322581, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24648431, Length=397, Percent_Identity=33.7531486146096, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24585488, Length=394, Percent_Identity=25.6345177664975, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 42788; Mature: 42657

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETGGPLKGLRVLEFTHMVMGPAAGLVLADLGAEVIKVEPIGGDKTRRLKGSGAGYFPM
CCCCCCCHHCHHHHHHHHHHHCHHHHHHHHHCCCEEEEEEECCCCCCEEECCCCCCCCCC
YNRNKKSLAVDLKSEEGKAIALALADQADIFIENFRPGALDALGFGYEALAARNPRLIYC
CCCCCCEEEEEEECCCCCEEEEEECCCCEEEEECCCCCCHHHHCCCHHHHHCCCCEEEEE
SEKGFLDGPYAHRTALDEVAQMMGGLAYMTGPPGRPLRAGASVIDVTGGMFGAIGVLAAL
CCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHH
NERQTTGKGRHVTASLFETTVFLVGQHIAQYAVTGSPAAPMPTRVSAWAVYDVFDAKDDE
HCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEEEEEECCCCCC
KVFVGVVSDSQWTAFCKAFDLADWAADASLAGNNDRVARREEILPRLRALFAGYSKQDLM
EEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
DKLEKIGLPFAPIQRPEDLLDDPHLLASGGLLDMELPEGGAVSLPALPITLDDHRPGLML
HHHHHCCCCCCCCCCCHHHCCCCCEEECCCEEEEECCCCCCEECCEEEEEECCCCCCCEE
DPPRIGAHSVEILKSLGHAQDQIDSLISRGLVEVSEAQPAE
CCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure 
SETGGPLKGLRVLEFTHMVMGPAAGLVLADLGAEVIKVEPIGGDKTRRLKGSGAGYFPM
CCCCCCHHCHHHHHHHHHHHCHHHHHHHHHCCCEEEEEEECCCCCCEEECCCCCCCCCC
YNRNKKSLAVDLKSEEGKAIALALADQADIFIENFRPGALDALGFGYEALAARNPRLIYC
CCCCCCEEEEEEECCCCCEEEEEECCCCEEEEECCCCCCHHHHCCCHHHHHCCCCEEEEE
SEKGFLDGPYAHRTALDEVAQMMGGLAYMTGPPGRPLRAGASVIDVTGGMFGAIGVLAAL
CCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHH
NERQTTGKGRHVTASLFETTVFLVGQHIAQYAVTGSPAAPMPTRVSAWAVYDVFDAKDDE
HCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEEEEEECCCCCC
KVFVGVVSDSQWTAFCKAFDLADWAADASLAGNNDRVARREEILPRLRALFAGYSKQDLM
EEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
DKLEKIGLPFAPIQRPEDLLDDPHLLASGGLLDMELPEGGAVSLPALPITLDDHRPGLML
HHHHHCCCCCCCCCCCHHHCCCCCEEECCCEEEEECCCCCCEECCEEEEEECCCCCCCEE
DPPRIGAHSVEILKSLGHAQDQIDSLISRGLVEVSEAQPAE
CCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]