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The map label for this gene is aroQ

Identifier: 114797900

GI number: 114797900

Start: 2350304

End: 2350747

Strand: Direct

Name: aroQ

Synonym: HNE_2248

Alternate gene names: 114797900

Gene position: 2350304-2350747 (Clockwise)

Preceding gene: 114797797

Following gene: 114797700

Centisome position: 63.44

GC content: 59.23

Gene sequence:

>444_bases
ATGTCGAAACCGGTATATGTCCTCGGCGGGCCGAACCTCAACCTTTTGGGTACGCGCGAGCCGGAAATCTACGGGCGGGA
TACGCTCGAGGATATCCACGCCCGACTCAGGGCGCTCGCTGGCGACGTGGCAATTGTCGCGCGCCAGACGAATTCTGAAG
GTGAGCTCGTGTCCTGGGTGCAGGAGGCTGCCCGAGACGGGCGGGCTCTGATCCTCAACGCAGCCGCCTACACACACACG
TCGATTGCGCTGCATGACGCCTTGAAAACATTGAAAATTCCACTAATCGAAGTTCACCTGTCGAACCCCGCTGCGCGCGA
AGCTTTCCGGCATGTGAATTACGTTGCGCCTGTTGCAGTTGGTACAATTGCCGGGCTAGGTGCCTATGGTTATGAACTCG
CGCTGAGCGCGGCCCTGAGGCTATCGGGAGAGGCTAGGAGCTAA

Upstream 100 bases:

>100_bases
CGATCTCGAGCGCCGCTCCGTTCAGTGTGATCTGCATCACCAAAATTCCCTGACTGTTGCCCTCTTGCCACGCTGGCCGT
TACAGCGCAAACGAAGGCGC

Downstream 100 bases:

>100_bases
ATATGAGTACTGCCAAGAACAAGCTGGACACGGGCCTGATCCGCGAACTGGCGGCCATCCTGCGGGAAGCCGACCTGGGT
GAGCTGGAGGTCGAACATGA

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MSKPVYVLGGPNLNLLGTREPEIYGRDTLEDIHARLRALAGDVAIVARQTNSEGELVSWVQEAARDGRALILNAAAYTHT
SIALHDALKTLKIPLIEVHLSNPAAREAFRHVNYVAPVAVGTIAGLGAYGYELALSAALRLSGEARS

Sequences:

>Translated_147_residues
MSKPVYVLGGPNLNLLGTREPEIYGRDTLEDIHARLRALAGDVAIVARQTNSEGELVSWVQEAARDGRALILNAAAYTHT
SIALHDALKTLKIPLIEVHLSNPAAREAFRHVNYVAPVAVGTIAGLGAYGYELALSAALRLSGEARS
>Mature_146_residues
SKPVYVLGGPNLNLLGTREPEIYGRDTLEDIHARLRALAGDVAIVARQTNSEGELVSWVQEAARDGRALILNAAAYTHTS
IALHDALKTLKIPLIEVHLSNPAAREAFRHVNYVAPVAVGTIAGLGAYGYELALSAALRLSGEARS

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_HYPNA (Q0C000)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760943.1
- ProteinModelPortal:   Q0C000
- SMR:   Q0C000
- STRING:   Q0C000
- GeneID:   4288088
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_2248
- TIGR:   HNE_2248
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- BioCyc:   HNEP81032:HNE_2248-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15694; Mature: 15563

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 24-24 ACT_SITE 99-99 BINDING 73-73 BINDING 79-79 BINDING 86-86 BINDING 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPVYVLGGPNLNLLGTREPEIYGRDTLEDIHARLRALAGDVAIVARQTNSEGELVSWV
CCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHH
QEAARDGRALILNAAAYTHTSIALHDALKTLKIPLIEVHLSNPAAREAFRHVNYVAPVAV
HHHHCCCCEEEEEECHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHCCHHHHHHH
GTIAGLGAYGYELALSAALRLSGEARS
HHHHHCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SKPVYVLGGPNLNLLGTREPEIYGRDTLEDIHARLRALAGDVAIVARQTNSEGELVSWV
CCCEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHH
QEAARDGRALILNAAAYTHTSIALHDALKTLKIPLIEVHLSNPAAREAFRHVNYVAPVAV
HHHHCCCCEEEEEECHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHCCHHHHHHH
GTIAGLGAYGYELALSAALRLSGEARS
HHHHHCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA