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The map label for this gene is fbcH [H]

Identifier: 114797363

GI number: 114797363

Start: 345281

End: 346240

Strand: Direct

Name: fbcH [H]

Synonym: HNE_0352

Alternate gene names: 114797363

Gene position: 345281-346240 (Clockwise)

Preceding gene: 114797745

Following gene: 114799462

Centisome position: 9.32

GC content: 64.27

Gene sequence:

>960_bases
ATGAAAACCTTCCGCATCCTCGCTGCTGGCCTGATGGGCCTGGCCTTTGCAGGCCTCGCCCATGCTGCAGGCGGCTCGAA
GCACCCGCACGGCCCCGAAGAAGGCTGGCCGTTTGAAGGCGTCACCGGTCAGTTTGACAAGGCGTCGGTCCAGCGTGGCT
ATCAGGTCTACAAGCAGGTCTGTTCCAGCTGCCACGGCATGAAGCTGATGAGCTACCGCAACCTCGGTGAGCCCGGCGGC
CCGTTCTATGATCCGGCCTATCCCAACCCGAACGACAACCCGTTCGTGAAGGCATTGGCGGCCGAGAACGAAGTCATGAA
CGCCACGCCCAACGACACGGGCGAGTATGACTATCGCCCCGCCATGCCGGCGGACCGTTTCCGCGCGCCGTTCCCGAACG
ACGCGGCGGCCCGCGCGGCCAATGGCGGCGCCCTGCCGCCCGATCTCTCGGTGATGGTCAAGGCCCGCCACTATGGCGCG
GACTATATCTTCGACCTGATGACCGGTTATCCCGACCCCACGCTGTTTGAAGACCGTGAAGTCCAGGAGAATGGCGAGAC
GCTTTACCAGAAAGTGCTCGACGTTTCGAAGTTCGAGAAGCTCGGCGACTACCGCCCCGAGCACACCTCCTACCTCGTCC
AGCCGGCTGGCCAGTACTACAACCCCTATATGGCGGGCGACACCACGCCCAACTATGAGGGCGACCCGCGCCATGCTCCG
CCCGGCGGCTTCCTCGCCATGGCCCCGCAACTGACGGACGGCCGCGTCGAGTATACCGACGGCACCGAGGCAACGGCTGA
GCAGATGGCCTATGACGTGGCCCAGTTCCTGGCCTGGGCGTCCGAGCCCAAGCTGGAAGCGCGCAAGCGCACGGGCCTGG
CCACCATGGCCTTCCTGCTGATCCTCACAACGCTGCTCTGGTTCTCCTACAAGCAGATCTGGCGCAAGGTTGAGCACTAG

Upstream 100 bases:

>100_bases
CTGCCGGAATCGATCCATAAATCCGTGCTGAAGCGTAAGCCCAAGGAAACGGGCAATGCAGTGCCGGCTGAGTAAGATGC
AAGCTGGGGAAAGAAAGAAC

Downstream 100 bases:

>100_bases
TCTCAGCCCCGCAGCATGAAACCTTCGATAGCCATCCGCAGGGCCACCCCTTCGGATGGCTTTCTCGTTGAGGGGCTGAC
GCGCCGCATCTGGACCGGCC

Product: putative ubiquinol-cytochrome c reductase, cytochrome c1

Products: Q; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MKTFRILAAGLMGLAFAGLAHAAGGSKHPHGPEEGWPFEGVTGQFDKASVQRGYQVYKQVCSSCHGMKLMSYRNLGEPGG
PFYDPAYPNPNDNPFVKALAAENEVMNATPNDTGEYDYRPAMPADRFRAPFPNDAAARAANGGALPPDLSVMVKARHYGA
DYIFDLMTGYPDPTLFEDREVQENGETLYQKVLDVSKFEKLGDYRPEHTSYLVQPAGQYYNPYMAGDTTPNYEGDPRHAP
PGGFLAMAPQLTDGRVEYTDGTEATAEQMAYDVAQFLAWASEPKLEARKRTGLATMAFLLILTTLLWFSYKQIWRKVEH

Sequences:

>Translated_319_residues
MKTFRILAAGLMGLAFAGLAHAAGGSKHPHGPEEGWPFEGVTGQFDKASVQRGYQVYKQVCSSCHGMKLMSYRNLGEPGG
PFYDPAYPNPNDNPFVKALAAENEVMNATPNDTGEYDYRPAMPADRFRAPFPNDAAARAANGGALPPDLSVMVKARHYGA
DYIFDLMTGYPDPTLFEDREVQENGETLYQKVLDVSKFEKLGDYRPEHTSYLVQPAGQYYNPYMAGDTTPNYEGDPRHAP
PGGFLAMAPQLTDGRVEYTDGTEATAEQMAYDVAQFLAWASEPKLEARKRTGLATMAFLLILTTLLWFSYKQIWRKVEH
>Mature_319_residues
MKTFRILAAGLMGLAFAGLAHAAGGSKHPHGPEEGWPFEGVTGQFDKASVQRGYQVYKQVCSSCHGMKLMSYRNLGEPGG
PFYDPAYPNPNDNPFVKALAAENEVMNATPNDTGEYDYRPAMPADRFRAPFPNDAAARAANGGALPPDLSVMVKARHYGA
DYIFDLMTGYPDPTLFEDREVQENGETLYQKVLDVSKFEKLGDYRPEHTSYLVQPAGQYYNPYMAGDTTPNYEGDPRHAP
PGGFLAMAPQLTDGRVEYTDGTEATAEQMAYDVAQFLAWASEPKLEARKRTGLATMAFLLILTTLLWFSYKQIWRKVEH

Specific function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c [H]

COG id: COG2857

COG function: function code C; Cytochrome c1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI21359867, Length=261, Percent_Identity=39.463601532567, Blast_Score=159, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17506225, Length=311, Percent_Identity=34.4051446945338, Blast_Score=127, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6324639, Length=287, Percent_Identity=37.9790940766551, Blast_Score=169, Evalue=7e-43,
Organism=Drosophila melanogaster, GI24658292, Length=311, Percent_Identity=34.4051446945338, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI21358225, Length=304, Percent_Identity=32.8947368421053, Blast_Score=138, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016175
- InterPro:   IPR005798
- InterPro:   IPR005797
- InterPro:   IPR002326
- InterPro:   IPR021157
- InterPro:   IPR009056
- InterPro:   IPR016174 [H]

Pfam domain/function: PF00032 Cytochrom_B_C; PF00033 Cytochrom_B_N; PF02167 Cytochrom_C1 [H]

EC number: 1.10.2.2

Molecular weight: Translated: 35362; Mature: 35362

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFRILAAGLMGLAFAGLAHAAGGSKHPHGPEEGWPFEGVTGQFDKASVQRGYQVYKQV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
CSSCHGMKLMSYRNLGEPGGPFYDPAYPNPNDNPFVKALAAENEVMNATPNDTGEYDYRP
HHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCCCCCCCCCCC
AMPADRFRAPFPNDAAARAANGGALPPDLSVMVKARHYGADYIFDLMTGYPDPTLFEDRE
CCCHHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCH
VQENGETLYQKVLDVSKFEKLGDYRPEHTSYLVQPAGQYYNPYMAGDTTPNYEGDPRHAP
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCCCCCEECCCCCCCCCCCCCCCC
PGGFLAMAPQLTDGRVEYTDGTEATAEQMAYDVAQFLAWASEPKLEARKRTGLATMAFLL
CCCEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ILTTLLWFSYKQIWRKVEH
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTFRILAAGLMGLAFAGLAHAAGGSKHPHGPEEGWPFEGVTGQFDKASVQRGYQVYKQV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
CSSCHGMKLMSYRNLGEPGGPFYDPAYPNPNDNPFVKALAAENEVMNATPNDTGEYDYRP
HHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCCCCCCCCCCC
AMPADRFRAPFPNDAAARAANGGALPPDLSVMVKARHYGADYIFDLMTGYPDPTLFEDRE
CCCHHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCH
VQENGETLYQKVLDVSKFEKLGDYRPEHTSYLVQPAGQYYNPYMAGDTTPNYEGDPRHAP
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCCCCCEECCCCCCCCCCCCCCCC
PGGFLAMAPQLTDGRVEYTDGTEATAEQMAYDVAQFLAWASEPKLEARKRTGLATMAFLL
CCCEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ILTTLLWFSYKQIWRKVEH
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: QH2; ferricytochrome c

Specific reaction: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2541921; 12597275 [H]