BacMap

Definition	Nitrosomonas eutropha C91, complete genome.
Accession	NC_008344
Length	2,661,057

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The map label for this gene is ccmA [H]

Identifier: 114331629

GI number: 114331629

Start: 1726657

End: 1727271

Strand: Reverse

Name: ccmA [H]

Synonym: Neut_1643

Alternate gene names: 114331629

Gene position: 1727271-1726657 (Counterclockwise)

Preceding gene: 114331630

Following gene: 114331628

Centisome position: 64.91

GC content: 47.97

Gene sequence:

>615_bases
ATGTTGACGGCCAGGAACCTGGAGTGTATACGAGGGGAGCATAAACTCTTCAGTAACATTTTCTTCTCAGTAAATCCCGG
TGAGCTGATGTTTGTTGGCGGACCTAACGGTAGCGGTAAAACCAGCTTGCTAAGATTGTTGTGTGGATTATCGTCACCTG
ATAGTGGTGAGATTCTCTGGAATGGAATGGATATTCGGGATCTGGACGGAGATTATCGTGGCATGATGACCTATCTAGGG
CATCTGGGTGGTATCAAGGATGATCTGACTGCTCTCGAGAATTTACGGATATCCTGTGCATTGGCTGATTGTGAGATTGA
TGAAAATCAAGCAGCAGATGCGTTAGGGCAGATTGGGCTGGCGGGGCGTGAGATGCTGCCGGCCAAAGTATTATCACAAG
GACAACGCAGACGGGTGGCTTTGGCGCGTCTGCTGGTGGTGCAGACTAGGTTGTGGATATTGGATGAGCCTTTGACCGCG
CTGGATACTGCAGCGGTGAAGCTGATTAAAGAGATACTGGAACATAATCTATCGAAAGGAGGCATGGTCATTATGACCAC
TCATCAGGAAATTGTCATGACTGCTGCAGCTGTTCATCATTTGACTTTATCCTGA

Upstream 100 bases:

>100_bases
AGAATGATTTTTATATATCCAAGCACTGGCAGCACCACTAAGAAATCAGCAATACGCTATAATCTCCAACTTTTATGATT
GCGGCTCAATTATTATTTAG

Downstream 100 bases:

>100_bases
TTCGATATGATCTGGTGGATAGTTAAACGGGATTTATTGCTGGCAATGCGCCGACGCTCTGATGTGTTGACAACGCTATT
TTTTTTCATAATAGTTGTCA

Product: cytochrome c biogenesis protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MLTARNLECIRGEHKLFSNIFFSVNPGELMFVGGPNGSGKTSLLRLLCGLSSPDSGEILWNGMDIRDLDGDYRGMMTYLG
HLGGIKDDLTALENLRISCALADCEIDENQAADALGQIGLAGREMLPAKVLSQGQRRRVALARLLVVQTRLWILDEPLTA
LDTAAVKLIKEILEHNLSKGGMVIMTTHQEIVMTAAAVHHLTLS

Sequences:

>Translated_204_residues
MLTARNLECIRGEHKLFSNIFFSVNPGELMFVGGPNGSGKTSLLRLLCGLSSPDSGEILWNGMDIRDLDGDYRGMMTYLG
HLGGIKDDLTALENLRISCALADCEIDENQAADALGQIGLAGREMLPAKVLSQGQRRRVALARLLVVQTRLWILDEPLTA
LDTAAVKLIKEILEHNLSKGGMVIMTTHQEIVMTAAAVHHLTLS
>Mature_204_residues
MLTARNLECIRGEHKLFSNIFFSVNPGELMFVGGPNGSGKTSLLRLLCGLSSPDSGEILWNGMDIRDLDGDYRGMMTYLG
HLGGIKDDLTALENLRISCALADCEIDENQAADALGQIGLAGREMLPAKVLSQGQRRRVALARLLVVQTRLWILDEPLTA
LDTAAVKLIKEILEHNLSKGGMVIMTTHQEIVMTAAAVHHLTLS

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI46592915, Length=184, Percent_Identity=31.5217391304348, Blast_Score=67, Evalue=9e-12,
Organism=Homo sapiens, GI46592898, Length=184, Percent_Identity=31.5217391304348, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI46592971, Length=184, Percent_Identity=31.5217391304348, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI46592978, Length=184, Percent_Identity=31.5217391304348, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI46592964, Length=183, Percent_Identity=30.6010928961749, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI46592956, Length=183, Percent_Identity=30.6010928961749, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI215820660, Length=167, Percent_Identity=31.7365269461078, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI20143975, Length=167, Percent_Identity=31.7365269461078, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI47078218, Length=167, Percent_Identity=29.3413173652695, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI45446740, Length=167, Percent_Identity=29.3413173652695, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI156105685, Length=190, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI87082064, Length=204, Percent_Identity=45.0980392156863, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI87081834, Length=181, Percent_Identity=33.7016574585635, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787029, Length=200, Percent_Identity=31.5, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788225, Length=180, Percent_Identity=33.8888888888889, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1789873, Length=202, Percent_Identity=30.6930693069307, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786698, Length=192, Percent_Identity=28.6458333333333, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788761, Length=194, Percent_Identity=31.4432989690722, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790467, Length=194, Percent_Identity=31.4432989690722, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1789672, Length=204, Percent_Identity=28.4313725490196, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789593, Length=193, Percent_Identity=29.5336787564767, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1787370, Length=193, Percent_Identity=30.5699481865285, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI87081782, Length=195, Percent_Identity=27.6923076923077, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI87081709, Length=161, Percent_Identity=30.4347826086957, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788897, Length=186, Percent_Identity=31.7204301075269, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI87081791, Length=203, Percent_Identity=30.0492610837438, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1786703, Length=190, Percent_Identity=33.6842105263158, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787105, Length=190, Percent_Identity=30, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790544, Length=198, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789991, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=1e-13,
Organism=Escherichia coli, GI1789032, Length=179, Percent_Identity=29.608938547486, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786253, Length=190, Percent_Identity=31.5789473684211, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787712, Length=190, Percent_Identity=29.4736842105263, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789586, Length=209, Percent_Identity=31.1004784688995, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788644, Length=197, Percent_Identity=28.9340101522843, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786872, Length=196, Percent_Identity=27.5510204081633, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788053, Length=168, Percent_Identity=31.547619047619, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786563, Length=204, Percent_Identity=30.8823529411765, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1786398, Length=181, Percent_Identity=27.0718232044199, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI48995001, Length=207, Percent_Identity=26.0869565217391, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789891, Length=195, Percent_Identity=29.2307692307692, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1786653, Length=205, Percent_Identity=26.8292682926829, Blast_Score=60, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71992290, Length=191, Percent_Identity=30.3664921465969, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17511077, Length=199, Percent_Identity=29.6482412060301, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193208177, Length=199, Percent_Identity=29.6482412060301, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565586, Length=177, Percent_Identity=27.1186440677966, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533592, Length=190, Percent_Identity=27.8947368421053, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI115533608, Length=166, Percent_Identity=30.7228915662651, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17555318, Length=183, Percent_Identity=30.6010928961749, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17541710, Length=194, Percent_Identity=26.2886597938144, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17559834, Length=180, Percent_Identity=29.4444444444444, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17569145, Length=186, Percent_Identity=27.4193548387097, Blast_Score=63, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323217, Length=195, Percent_Identity=28.7179487179487, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323959, Length=177, Percent_Identity=26.5536723163842, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28574533, Length=185, Percent_Identity=31.3513513513514, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24666092, Length=188, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28574150, Length=172, Percent_Identity=30.8139534883721, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007328, Length=172, Percent_Identity=30.8139534883721, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19920532, Length=173, Percent_Identity=28.9017341040462, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24580930, Length=173, Percent_Identity=28.9017341040462, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28574744, Length=181, Percent_Identity=32.0441988950276, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI85726357, Length=188, Percent_Identity=29.2553191489362, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 22207; Mature: 22207

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTARNLECIRGEHKLFSNIFFSVNPGELMFVGGPNGSGKTSLLRLLCGLSSPDSGEILW
CCCCCCHHHHHHHHHHHHHHEEEECCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEE
NGMDIRDLDGDYRGMMTYLGHLGGIKDDLTALENLRISCALADCEIDENQAADALGQIGL
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHCCC
AGREMLPAKVLSQGQRRRVALARLLVVQTRLWILDEPLTALDTAAVKLIKEILEHNLSKG
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
GMVIMTTHQEIVMTAAAVHHLTLS
CEEEEECHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTARNLECIRGEHKLFSNIFFSVNPGELMFVGGPNGSGKTSLLRLLCGLSSPDSGEILW
CCCCCCHHHHHHHHHHHHHHEEEECCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEE
NGMDIRDLDGDYRGMMTYLGHLGGIKDDLTALENLRISCALADCEIDENQAADALGQIGL
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHCCC
AGREMLPAKVLSQGQRRRVALARLLVVQTRLWILDEPLTALDTAAVKLIKEILEHNLSKG
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
GMVIMTTHQEIVMTAAAVHHLTLS
CEEEEECHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]