Click here to switch to the map view.

The map label for this gene is ccmB [H]

Identifier: 114331628

GI number: 114331628

Start: 1725991

End: 1726650

Strand: Reverse

Name: ccmB [H]

Synonym: Neut_1642

Alternate gene names: 114331628

Gene position: 1726650-1725991 (Counterclockwise)

Preceding gene: 114331629

Following gene: 114331627

Centisome position: 64.89

GC content: 50.76

Gene sequence:

>660_bases
ATGATCTGGTGGATAGTTAAACGGGATTTATTGCTGGCAATGCGCCGACGCTCTGATGTGTTGACAACGCTATTTTTTTT
CATAATAGTTGTCAGCTTGTTTCCATTGGGTGTGGGGCCTGAACCCAGCATACTGCGGACAATGGCCTCGGGTGTGGTCT
GGGTGGCAGCTTTGCTGGCTTCGATGTTATCACTTGGACGTATGTTCTCCAGTGATTATGCAGATGGCACCTTGGAGCAA
ATGCTGCTTTCCCCTGTTTCCCTGGCGGCGCTGGTCACCGGGAAAGCAATATCACACTGGTTGGTAACAGGGGTTCCTCT
GGTATTGATGGCCCCGGTATTGGGGATTCAGTATGACTTAGCCGGAGATGCCTTGCTTGTGCTGACGCTTTCATTGCTGC
TGGGAACTCCTGTACTAAGTTTGATCGGTGCAATCGGTGCTGCGTTAACGCTGGGATTAAGAGGAGGGGGGGTATTAGTG
TCGATACTGGTTTTGCCGCTCTACATTCCGGTATTAATTTTTGGTACAGGCGCGGTTGAAGCGAGTAGCGCCGGGATGGA
GTTTGGGGCCCATTTTTCGATACTGGGTGCACTTTTGCTGGTTTCTATCGTTTTTTCACCTTGGGCAACAGCTGCCTCTC
TCCGGATATCCATGAGCTGA

Upstream 100 bases:

>100_bases
ACATAATCTATCGAAAGGAGGCATGGTCATTATGACCACTCATCAGGAAATTGTCATGACTGCTGCAGCTGTTCATCATT
TGACTTTATCCTGATTCGAT

Downstream 100 bases:

>100_bases
TAGAAAGGATGTGCCCAGAAATAATAGTGATGTTGCGTTTGTTGGTATGGTAGTAGAGCGTAATTTTATCTACTGGATCA
ATTCAGAGAGAATATTCAGA

Product: heme exporter protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MIWWIVKRDLLLAMRRRSDVLTTLFFFIIVVSLFPLGVGPEPSILRTMASGVVWVAALLASMLSLGRMFSSDYADGTLEQ
MLLSPVSLAALVTGKAISHWLVTGVPLVLMAPVLGIQYDLAGDALLVLTLSLLLGTPVLSLIGAIGAALTLGLRGGGVLV
SILVLPLYIPVLIFGTGAVEASSAGMEFGAHFSILGALLLVSIVFSPWATAASLRISMS

Sequences:

>Translated_219_residues
MIWWIVKRDLLLAMRRRSDVLTTLFFFIIVVSLFPLGVGPEPSILRTMASGVVWVAALLASMLSLGRMFSSDYADGTLEQ
MLLSPVSLAALVTGKAISHWLVTGVPLVLMAPVLGIQYDLAGDALLVLTLSLLLGTPVLSLIGAIGAALTLGLRGGGVLV
SILVLPLYIPVLIFGTGAVEASSAGMEFGAHFSILGALLLVSIVFSPWATAASLRISMS
>Mature_219_residues
MIWWIVKRDLLLAMRRRSDVLTTLFFFIIVVSLFPLGVGPEPSILRTMASGVVWVAALLASMLSLGRMFSSDYADGTLEQ
MLLSPVSLAALVTGKAISHWLVTGVPLVLMAPVLGIQYDLAGDALLVLTLSLLLGTPVLSLIGAIGAALTLGLRGGGVLV
SILVLPLYIPVLIFGTGAVEASSAGMEFGAHFSILGALLLVSIVFSPWATAASLRISMS

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=219, Percent_Identity=48.4018264840183, Blast_Score=160, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22976; Mature: 22976

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWWIVKRDLLLAMRRRSDVLTTLFFFIIVVSLFPLGVGPEPSILRTMASGVVWVAALLA
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
SMLSLGRMFSSDYADGTLEQMLLSPVSLAALVTGKAISHWLVTGVPLVLMAPVLGIQYDL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECC
AGDALLVLTLSLLLGTPVLSLIGAIGAALTLGLRGGGVLVSILVLPLYIPVLIFGTGAVE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
ASSAGMEFGAHFSILGALLLVSIVFSPWATAASLRISMS
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEECC
>Mature Secondary Structure
MIWWIVKRDLLLAMRRRSDVLTTLFFFIIVVSLFPLGVGPEPSILRTMASGVVWVAALLA
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
SMLSLGRMFSSDYADGTLEQMLLSPVSLAALVTGKAISHWLVTGVPLVLMAPVLGIQYDL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECC
AGDALLVLTLSLLLGTPVLSLIGAIGAALTLGLRGGGVLVSILVLPLYIPVLIFGTGAVE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
ASSAGMEFGAHFSILGALLLVSIVFSPWATAASLRISMS
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]