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The map label for this gene is int [H]

Identifier: 114331357

GI number: 114331357

Start: 1435095

End: 1436084

Strand: Reverse

Name: int [H]

Synonym: Neut_1366

Alternate gene names: 114331357

Gene position: 1436084-1435095 (Counterclockwise)

Preceding gene: 114331369

Following gene: 114331355

Centisome position: 53.97

GC content: 50.1

Gene sequence:

>990_bases
ATGAATAAAATGCCACCATCTCATGCGCCGACTTCACCCAAGTTACTTGATCAGCTTCGTGACAAGCTGCGTTTAAAGCA
TTACAGCATAAGGACTGAGGTGCAATATGTCCAGTGGGTACGGCGCTTCATTTTATTTCATGATAAACGGCATCCACAGG
AGATGGGGGCCGGGGAGGTGGAGGCTTTTTTGACACATCTTGCTGTATCGGGCAGGGTGGCGGCATCAACGCAGAATCAG
GCACTTTCAGCTTTGCTGTTTTTATATCGGGAAGTGCTGGAAATCGATTTGCCCTGGCTTGACAACGTGGTGCGAGCAAA
GCGGCCGGCACGTTTGCCGGTGGTGCTGACGCATAATGAGATACAGGCGGTGTTGGGTCGGATGACAGGAGCACATGGCT
TAATGGCGCGCTTGCTGTATGGCACCGGTATGCGGTTAATGGAATGTGTACGTTTGCGGGTTAAAGATGTGGATTTTGAG
CGAGCTGAAATACTGGTGCGCGATGGCAAGGGGGCAAAAGATCGGGTAACAATGTTGCCGCAAAGTTTGATCCCGGTTTT
GAATGAGCATATACGACACCGGCGATTGCTCTACGAGGATGATCTGGCCAAAGATATGGCCGCAGTGTATTTACCGGATG
CACTGGAGCGAAAATATCCAAAGGCGGCGACTGACTGGATTTGGCAGTATATTTTTGTTGCCAAGAGCTATTCAGTTGAT
CCGCGCAGTGGTGTAGAGCGACGTCATCATATGGATGAAAAATTGCTGCAGCGTGCGATGAAGAAGGCAGTGCTGGCAGC
GGGAGTGACCAAGCCAGCTACACCACATACCCTGCGCCATTCCTTTGCCACGCATCTTTTACAAGCTGGCTATGATATTC
GTACAGTGCAAGAGCTATTGGGGCATAGTGATGTTGCCACCACAATGATTTATACCCATGTACTGAACAAAGGTGGCAAA
GGTGTGATCAGCCCGCTGGATCATCTGTAA

Upstream 100 bases:

>100_bases
TCGCCTAACGTTCAGTATACACCGCAAGCGGTGTATACTTCTTCACAAGAAGGTGTATAACAAATTTATTATTTGATAAC
ACAATGAATTTAAAAAAAGT

Downstream 100 bases:

>100_bases
AACTGATTAATCAGAATGTTTCCAGTTGCCTAACGCTTATAGGCAGTTCAAGGACAAAGTTAGCAAAAGAATGGAAGCTT
TTGAGCAAACTTTAAACGCA

Product: integron integrase

Products: NA

Alternate protein names: E2 protein [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNKMPPSHAPTSPKLLDQLRDKLRLKHYSIRTEVQYVQWVRRFILFHDKRHPQEMGAGEVEAFLTHLAVSGRVAASTQNQ
ALSALLFLYREVLEIDLPWLDNVVRAKRPARLPVVLTHNEIQAVLGRMTGAHGLMARLLYGTGMRLMECVRLRVKDVDFE
RAEILVRDGKGAKDRVTMLPQSLIPVLNEHIRHRRLLYEDDLAKDMAAVYLPDALERKYPKAATDWIWQYIFVAKSYSVD
PRSGVERRHHMDEKLLQRAMKKAVLAAGVTKPATPHTLRHSFATHLLQAGYDIRTVQELLGHSDVATTMIYTHVLNKGGK
GVISPLDHL

Sequences:

>Translated_329_residues
MNKMPPSHAPTSPKLLDQLRDKLRLKHYSIRTEVQYVQWVRRFILFHDKRHPQEMGAGEVEAFLTHLAVSGRVAASTQNQ
ALSALLFLYREVLEIDLPWLDNVVRAKRPARLPVVLTHNEIQAVLGRMTGAHGLMARLLYGTGMRLMECVRLRVKDVDFE
RAEILVRDGKGAKDRVTMLPQSLIPVLNEHIRHRRLLYEDDLAKDMAAVYLPDALERKYPKAATDWIWQYIFVAKSYSVD
PRSGVERRHHMDEKLLQRAMKKAVLAAGVTKPATPHTLRHSFATHLLQAGYDIRTVQELLGHSDVATTMIYTHVLNKGGK
GVISPLDHL
>Mature_329_residues
MNKMPPSHAPTSPKLLDQLRDKLRLKHYSIRTEVQYVQWVRRFILFHDKRHPQEMGAGEVEAFLTHLAVSGRVAASTQNQ
ALSALLFLYREVLEIDLPWLDNVVRAKRPARLPVVLTHNEIQAVLGRMTGAHGLMARLLYGTGMRLMECVRLRVKDVDFE
RAEILVRDGKGAKDRVTMLPQSLIPVLNEHIRHRRLLYEDDLAKDMAAVYLPDALERKYPKAATDWIWQYIFVAKSYSVD
PRSGVERRHHMDEKLLQRAMKKAVLAAGVTKPATPHTLRHSFATHLLQAGYDIRTVQELLGHSDVATTMIYTHVLNKGGK
GVISPLDHL

Specific function: Putative integrase believed to be involved in the insertion of antibiotic resistance genes into plasmids and transposons [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=257, Percent_Identity=30.7392996108949, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790244, Length=180, Percent_Identity=31.1111111111111, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR011946
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 37543; Mature: 37543

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKMPPSHAPTSPKLLDQLRDKLRLKHYSIRTEVQYVQWVRRFILFHDKRHPQEMGAGEV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHH
EAFLTHLAVSGRVAASTQNQALSALLFLYREVLEIDLPWLDNVVRAKRPARLPVVLTHNE
HHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEHHH
IQAVLGRMTGAHGLMARLLYGTGMRLMECVRLRVKDVDFERAEILVRDGKGAKDRVTMLP
HHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHEEEECCCCCHHHHHHHH
QSLIPVLNEHIRHRRLLYEDDLAKDMAAVYLPDALERKYPKAATDWIWQYIFVAKSYSVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHCCCCC
PRSGVERRHHMDEKLLQRAMKKAVLAAGVTKPATPHTLRHSFATHLLQAGYDIRTVQELL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
GHSDVATTMIYTHVLNKGGKGVISPLDHL
CCCHHHHHHHHHHHHHCCCCCCCCHHCCC
>Mature Secondary Structure
MNKMPPSHAPTSPKLLDQLRDKLRLKHYSIRTEVQYVQWVRRFILFHDKRHPQEMGAGEV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHH
EAFLTHLAVSGRVAASTQNQALSALLFLYREVLEIDLPWLDNVVRAKRPARLPVVLTHNE
HHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEHHH
IQAVLGRMTGAHGLMARLLYGTGMRLMECVRLRVKDVDFERAEILVRDGKGAKDRVTMLP
HHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHEEEECCCCCHHHHHHHH
QSLIPVLNEHIRHRRLLYEDDLAKDMAAVYLPDALERKYPKAATDWIWQYIFVAKSYSVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHCCCCC
PRSGVERRHHMDEKLLQRAMKKAVLAAGVTKPATPHTLRHSFATHLLQAGYDIRTVQELL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
GHSDVATTMIYTHVLNKGGKGVISPLDHL
CCCHHHHHHHHHHHHHCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2821509; 2823258; 3054482; 8195081; 2188588 [H]