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The map label for this gene is ycfH [H]

Identifier: 114331279

GI number: 114331279

Start: 1345908

End: 1346672

Strand: Reverse

Name: ycfH [H]

Synonym: Neut_1285

Alternate gene names: 114331279

Gene position: 1346672-1345908 (Counterclockwise)

Preceding gene: 114331280

Following gene: 114331278

Centisome position: 50.61

GC content: 48.63

Gene sequence:

>765_bases
ATGTTTGTTGATTCTCATTGTCACCTTGATTTTCCTGATCTGGCCAGTAACCTGAATGGGTTGCTGACGAATATGCAAAT
CAGTCAGGTCACACATGCTTTATGCGTTGCAGTTAATCTGGAAAATTTTCCGCGCGTGCGCGCACTGGCTGAATCACATC
CGAATCTGTTTGCTTCGGTGGGGGTGCATCCCGACTACGAAGACACGGCAGAACCTGAAGTTGAACAGTTGCTGGAGCTG
GCAAATCACGACAAGATAGTTGCGCTGGGAGAAACCGGACTGGATTATTTTCGGCTGAAAGGTGATCTTGAATGGCAGCG
CGAAAGGTTCCGGCGACATATTCGTGCTGCCAGGCAATGCGATAAACCGTTGATCATCCATACTCGCGCAGCGGCTGAAG
ATACATTGCGTATTATGAAAGAAGAGGGGGCAGATCAAGTCGGTGGTGTGATGCATTGCTTTACTGAATCCTGGGAAATC
GCCCAGCGTGCGCTCGATTTAAATTTTTACATCTCGTTCTCCGGGATTGTGACATTCAAGAATGCGGCAATTATTAAAGA
GGTGGCAAAGAAAGTACCAGCCGGCAAGATGCTGATCGAGACGGATTCTCCTTACCTTGCGCCCGTCCCTCATCGGGGCG
AAACTAATCAACCTGCATTTGTCCGGCATGTTGCCGAGGAAATCGCTCGGTTGCGTGAAACGGATGTTGCTGAAATTGCT
GCGGTAACAACCAATAATTTCTTCAACTTGTTCAAGGTGACCTGA

Upstream 100 bases:

>100_bases
TTGATTTGGTGGGAGAGGCTCCTGGATCCTGAGCGGAAGTTATTTAGGCTTTTCCAATCTGGTTACTTAAATATAAAAAT
CAAACTGATGCGTAAATCTT

Downstream 100 bases:

>100_bases
AATGAACAAATATTTGTGGAATCAGTGGAGTATTGTATCAGTCATCACCCTGTTGTGTGCCTTTTGCCTGTACTTGCCTG
CTTACGCCGGTGCAGATGAG

Product: hydrolase, TatD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MFVDSHCHLDFPDLASNLNGLLTNMQISQVTHALCVAVNLENFPRVRALAESHPNLFASVGVHPDYEDTAEPEVEQLLEL
ANHDKIVALGETGLDYFRLKGDLEWQRERFRRHIRAARQCDKPLIIHTRAAAEDTLRIMKEEGADQVGGVMHCFTESWEI
AQRALDLNFYISFSGIVTFKNAAIIKEVAKKVPAGKMLIETDSPYLAPVPHRGETNQPAFVRHVAEEIARLRETDVAEIA
AVTTNNFFNLFKVT

Sequences:

>Translated_254_residues
MFVDSHCHLDFPDLASNLNGLLTNMQISQVTHALCVAVNLENFPRVRALAESHPNLFASVGVHPDYEDTAEPEVEQLLEL
ANHDKIVALGETGLDYFRLKGDLEWQRERFRRHIRAARQCDKPLIIHTRAAAEDTLRIMKEEGADQVGGVMHCFTESWEI
AQRALDLNFYISFSGIVTFKNAAIIKEVAKKVPAGKMLIETDSPYLAPVPHRGETNQPAFVRHVAEEIARLRETDVAEIA
AVTTNNFFNLFKVT
>Mature_254_residues
MFVDSHCHLDFPDLASNLNGLLTNMQISQVTHALCVAVNLENFPRVRALAESHPNLFASVGVHPDYEDTAEPEVEQLLEL
ANHDKIVALGETGLDYFRLKGDLEWQRERFRRHIRAARQCDKPLIIHTRAAAEDTLRIMKEEGADQVGGVMHCFTESWEI
AQRALDLNFYISFSGIVTFKNAAIIKEVAKKVPAGKMLIETDSPYLAPVPHRGETNQPAFVRHVAEEIARLRETDVAEIA
AVTTNNFFNLFKVT

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=267, Percent_Identity=28.0898876404494, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI225903439, Length=243, Percent_Identity=30.0411522633745, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI14042943, Length=252, Percent_Identity=29.3650793650794, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI110349730, Length=264, Percent_Identity=27.6515151515151, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI110349734, Length=264, Percent_Identity=27.6515151515151, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI226061853, Length=269, Percent_Identity=27.1375464684015, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI226061614, Length=255, Percent_Identity=27.0588235294118, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI226061595, Length=226, Percent_Identity=26.1061946902655, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1787342, Length=257, Percent_Identity=47.8599221789883, Blast_Score=230, Evalue=6e-62,
Organism=Escherichia coli, GI87082439, Length=256, Percent_Identity=31.640625, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI48994985, Length=230, Percent_Identity=32.1739130434783, Blast_Score=112, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17559024, Length=280, Percent_Identity=27.1428571428571, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17565396, Length=304, Percent_Identity=27.9605263157895, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71980746, Length=264, Percent_Identity=25.7575757575758, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17543026, Length=296, Percent_Identity=26.6891891891892, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221330018, Length=255, Percent_Identity=29.8039215686275, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24586117, Length=255, Percent_Identity=29.8039215686275, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24648690, Length=286, Percent_Identity=24.1258741258741, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28590; Mature: 28590

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDSHCHLDFPDLASNLNGLLTNMQISQVTHALCVAVNLENFPRVRALAESHPNLFASV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHCCCCEEEEC
GVHPDYEDTAEPEVEQLLELANHDKIVALGETGLDYFRLKGDLEWQRERFRRHIRAARQC
CCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHC
DKPLIIHTRAAAEDTLRIMKEEGADQVGGVMHCFTESWEIAQRALDLNFYISFSGIVTFK
CCCEEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEEEEC
NAAIIKEVAKKVPAGKMLIETDSPYLAPVPHRGETNQPAFVRHVAEEIARLRETDVAEIA
HHHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
AVTTNNFFNLFKVT
HHCCCCCEEEEEEC
>Mature Secondary Structure
MFVDSHCHLDFPDLASNLNGLLTNMQISQVTHALCVAVNLENFPRVRALAESHPNLFASV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHCCCCEEEEC
GVHPDYEDTAEPEVEQLLELANHDKIVALGETGLDYFRLKGDLEWQRERFRRHIRAARQC
CCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHC
DKPLIIHTRAAAEDTLRIMKEEGADQVGGVMHCFTESWEIAQRALDLNFYISFSGIVTFK
CCCEEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEEEEC
NAAIIKEVAKKVPAGKMLIETDSPYLAPVPHRGETNQPAFVRHVAEEIARLRETDVAEIA
HHHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
AVTTNNFFNLFKVT
HHCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]