Click here to switch to the map view.

The map label for this gene is dac [H]

Identifier: 113477585

GI number: 113477585

Start: 6428236

End: 6429699

Strand: Reverse

Name: dac [H]

Synonym: Tery_4167

Alternate gene names: 113477585

Gene position: 6429699-6428236 (Counterclockwise)

Preceding gene: 113477586

Following gene: 113477584

Centisome position: 82.96

GC content: 32.51

Gene sequence:

>1464_bases
ATGTTAAAAATTTTCCTTAAACAAATTACAATTACTTTCTTGATCATATTTATAAATTCATTAATAGCACTTAGCCAAGA
AACGACTAGAAAAATTTGTCCGATAGAATTAAATAATGCTATTAATTCTATAATAAATCGCCCAATATTTAATCGCTCTC
GGTGGGGAATTTTAGTGGAAACTTTATCTGGAAAAAGGAAAATTTATAGCCGAGATGCTGAATATTATTTTACCCCTGCC
TCTACAGCTAAACTATTAACAACTGCAGCAGTATTAAAAGAACTAAAACCTAATTTTAGAATTAGAACTTCTATTTATGG
TGATGGGAAAGGTAATATATATATTGTGGGACGAGGAGATCCTAGTTTAGCAGAAACTCAATTAAAAAGTTTGGCTGAAC
AACTAAAAGAGGGGGGTATAGAAAATATTAATCAACTAATTTCTGATGATACTTATTTTCAAGGAATGGCAGTTAATTCT
AATTGGGAATGGGAAGATGTCCAAGCTGGTTATGGGGCACCAATTAATAGTTTAATATTTAATCAAAATGCTATAGATTT
AGTTTTATCGCCTCAAGGTAATGGTCAACCTTTAAAAGTTACTTTTGTTAATCCGGCGGAAAGTAAAAAATGGCAAATTG
AAAATAATTCGGTGACTGTAGCGACAAATAAAAAAGAGTTTGTTGAAGTAGGGCGAGATTTTATTCAACCAATAATTCGT
ATATCTGGGCAACTCCGAATTGGCTCGGCATCGGAACCTGTTTATGTGGCAGTTGTGGAACCAGCCGATAATTTTTTAAA
TAATTTTCGTCGGGTTTTAGAGTTAGAAGGAATTAGTGTTTCTCGAATAGTTAAAAGTTCACAAATAACTTCTAATTTAA
ACTTGACTGAATTAGCTTTTGTCGAGTCTCCTACGGTGGGAGAACTAATAGAGGAAGTAAATAAAAAAAGTAATAATGTT
TATGCAGAAGCTTTATTACGTCAACTAGGGGTTAGGAGTAAATTAGTTCCTAATAAAAAATCTGACTATCAGACTTTGGC
AAAAAGTTTGGAGGAGGTAAAAGTAATTTTGACTAGGTTAGGAGTTACTCCCAATAGTTTTAGATTAAATGATGGTTCTG
GTTTGTCTCGTCATAATTTAGTTAGTCCGGAGGCTTTGGTACAAACTCTCAGAATTATGGCTAATTCTCCCTGGGCTAAT
GCTTATAGAAATTCTTTACCTATTGCTGGTGTCAGTGGTACATTAAGTCGGCGTTTTATAAATAGTTTTGCTACCGGAAA
TATACAAGCAAAAACAGGAACAATTAGTGGGGTTTCTGGTTTGGCAGGATATGTGCAACCTATTAATTTTGAACCTTTAG
TTTTTAGTGTTATTGTTAATCAATCTGATTTAGAAACTAAATATTTAAGAAATGCTATTGATGAAATTGTTTTGCTTTTT
ACTCAGTTAAAGTTTTGCAGTTAA

Upstream 100 bases:

>100_bases
TTTTATTTTTACTTCCCCCTTACTTCCCTAATTATAAATTAAAAAATGCAGTAAAAACTCAGAAAGCTTAGTATTATACT
CTATTTTTAGTAGATAGCAA

Downstream 100 bases:

>100_bases
AAGAAAAAAATAAATTAAATTTTAGTTGGAAACAAGTTAATAATTATGCTAATGCTATTATTAGTTAGTAATTGATATAA
ATAGGATGCTCTCTGACAAT

Product: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein; PBP [H]

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MLKIFLKQITITFLIIFINSLIALSQETTRKICPIELNNAINSIINRPIFNRSRWGILVETLSGKRKIYSRDAEYYFTPA
STAKLLTTAAVLKELKPNFRIRTSIYGDGKGNIYIVGRGDPSLAETQLKSLAEQLKEGGIENINQLISDDTYFQGMAVNS
NWEWEDVQAGYGAPINSLIFNQNAIDLVLSPQGNGQPLKVTFVNPAESKKWQIENNSVTVATNKKEFVEVGRDFIQPIIR
ISGQLRIGSASEPVYVAVVEPADNFLNNFRRVLELEGISVSRIVKSSQITSNLNLTELAFVESPTVGELIEEVNKKSNNV
YAEALLRQLGVRSKLVPNKKSDYQTLAKSLEEVKVILTRLGVTPNSFRLNDGSGLSRHNLVSPEALVQTLRIMANSPWAN
AYRNSLPIAGVSGTLSRRFINSFATGNIQAKTGTISGVSGLAGYVQPINFEPLVFSVIVNQSDLETKYLRNAIDEIVLLF
TQLKFCS

Sequences:

>Translated_487_residues
MLKIFLKQITITFLIIFINSLIALSQETTRKICPIELNNAINSIINRPIFNRSRWGILVETLSGKRKIYSRDAEYYFTPA
STAKLLTTAAVLKELKPNFRIRTSIYGDGKGNIYIVGRGDPSLAETQLKSLAEQLKEGGIENINQLISDDTYFQGMAVNS
NWEWEDVQAGYGAPINSLIFNQNAIDLVLSPQGNGQPLKVTFVNPAESKKWQIENNSVTVATNKKEFVEVGRDFIQPIIR
ISGQLRIGSASEPVYVAVVEPADNFLNNFRRVLELEGISVSRIVKSSQITSNLNLTELAFVESPTVGELIEEVNKKSNNV
YAEALLRQLGVRSKLVPNKKSDYQTLAKSLEEVKVILTRLGVTPNSFRLNDGSGLSRHNLVSPEALVQTLRIMANSPWAN
AYRNSLPIAGVSGTLSRRFINSFATGNIQAKTGTISGVSGLAGYVQPINFEPLVFSVIVNQSDLETKYLRNAIDEIVLLF
TQLKFCS
>Mature_487_residues
MLKIFLKQITITFLIIFINSLIALSQETTRKICPIELNNAINSIINRPIFNRSRWGILVETLSGKRKIYSRDAEYYFTPA
STAKLLTTAAVLKELKPNFRIRTSIYGDGKGNIYIVGRGDPSLAETQLKSLAEQLKEGGIENINQLISDDTYFQGMAVNS
NWEWEDVQAGYGAPINSLIFNQNAIDLVLSPQGNGQPLKVTFVNPAESKKWQIENNSVTVATNKKEFVEVGRDFIQPIIR
ISGQLRIGSASEPVYVAVVEPADNFLNNFRRVLELEGISVSRIVKSSQITSNLNLTELAFVESPTVGELIEEVNKKSNNV
YAEALLRQLGVRSKLVPNKKSDYQTLAKSLEEVKVILTRLGVTPNSFRLNDGSGLSRHNLVSPEALVQTLRIMANSPWAN
AYRNSLPIAGVSGTLSRRFINSFATGNIQAKTGTISGVSGLAGYVQPINFEPLVFSVIVNQSDLETKYLRNAIDEIVLLF
TQLKFCS

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG2027

COG function: function code M; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S13 family [H]

Homologues:

Organism=Escherichia coli, GI1789573, Length=410, Percent_Identity=26.0975609756098, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR000667 [H]

Pfam domain/function: PF02113 Peptidase_S13 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 53982; Mature: 53982

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIFLKQITITFLIIFINSLIALSQETTRKICPIELNNAINSIINRPIFNRSRWGILVE
CHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEHHHHHHHHHCCCCCCCCCCCEEEE
TLSGKRKIYSRDAEYYFTPASTAKLLTTAAVLKELKPNFRIRTSIYGDGKGNIYIVGRGD
ECCCCHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCC
PSLAETQLKSLAEQLKEGGIENINQLISDDTYFQGMAVNSNWEWEDVQAGYGAPINSLIF
CCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEEECCCCCHHHCCCCCCCCHHHHHC
NQNAIDLVLSPQGNGQPLKVTFVNPAESKKWQIENNSVTVATNKKEFVEVGRDFIQPIIR
CCCCEEEEECCCCCCCEEEEEEECCCCCCCEEEECCEEEEEECHHHHHHHHHHHHHHHHH
ISGQLRIGSASEPVYVAVVEPADNFLNNFRRVLELEGISVSRIVKSSQITSNLNLTELAF
HCCCEEECCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEE
VESPTVGELIEEVNKKSNNVYAEALLRQLGVRSKLVPNKKSDYQTLAKSLEEVKVILTRL
ECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHH
GVTPNSFRLNDGSGLSRHNLVSPEALVQTLRIMANSPWANAYRNSLPIAGVSGTLSRRFI
CCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHH
NSFATGNIQAKTGTISGVSGLAGYVQPINFEPLVFSVIVNQSDLETKYLRNAIDEIVLLF
HHHCCCCEEEECCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
TQLKFCS
HHHHHCC
>Mature Secondary Structure
MLKIFLKQITITFLIIFINSLIALSQETTRKICPIELNNAINSIINRPIFNRSRWGILVE
CHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEHHHHHHHHHCCCCCCCCCCCEEEE
TLSGKRKIYSRDAEYYFTPASTAKLLTTAAVLKELKPNFRIRTSIYGDGKGNIYIVGRGD
ECCCCHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCC
PSLAETQLKSLAEQLKEGGIENINQLISDDTYFQGMAVNSNWEWEDVQAGYGAPINSLIF
CCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEEECCCCCHHHCCCCCCCCHHHHHC
NQNAIDLVLSPQGNGQPLKVTFVNPAESKKWQIENNSVTVATNKKEFVEVGRDFIQPIIR
CCCCEEEEECCCCCCCEEEEEEECCCCCCCEEEECCEEEEEECHHHHHHHHHHHHHHHHH
ISGQLRIGSASEPVYVAVVEPADNFLNNFRRVLELEGISVSRIVKSSQITSNLNLTELAF
HCCCEEECCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEE
VESPTVGELIEEVNKKSNNVYAEALLRQLGVRSKLVPNKKSDYQTLAKSLEEVKVILTRL
ECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHH
GVTPNSFRLNDGSGLSRHNLVSPEALVQTLRIMANSPWANAYRNSLPIAGVSGTLSRRFI
CCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHH
NSFATGNIQAKTGTISGVSGLAGYVQPINFEPLVFSVIVNQSDLETKYLRNAIDEIVLLF
HHHCCCCEEEECCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
TQLKFCS
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1554361; 7305936 [H]