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The map label for this gene is cobQ

Identifier: 113477396

GI number: 113477396

Start: 6118318

End: 6119784

Strand: Reverse

Name: cobQ

Synonym: Tery_3957

Alternate gene names: 113477396

Gene position: 6119784-6118318 (Counterclockwise)

Preceding gene: 113477398

Following gene: 113477395

Centisome position: 78.96

GC content: 34.08

Gene sequence:

>1467_bases
ATGAAAGCAATTATGGTAGTGGGAACTACTTCCCATGCCGGAAAATCTCTAATTACTACAGCCATCTGTAGAATTTTATC
ACGTCGTGGTTGGAAAGTCACCCCCTTCAAAGGACAAAATATGGCTTTGAACTCCTATGTCACATCTACCGGTGGAGAAA
TGGGTCATGCTCAAGCAGTACAAGCTTGGGCCGCAGGTGTAACTCCTGCAATAGAAATGAACCCAATTTTATTAAAGCCT
CAAGGAGATATGACTTCTCAAGTTATTATTAAAGGAAAAGCTAGTGGTACTGTAGGAGCTGTAGATTATTATCAGCAGTA
TTTTGATATTGGTTGGAATGCCATCCAAGAATCTTTAGAAACTTTATCTCAAGAGTTTAACATGATAGTTTGTGAAGGAG
CCGGTAGTCCAGCAGAAATAAATCTGAAGCACCGAGATCTAACTAATATGCGAGTCGCCAAACATTTGAATGCCTCTACA
ATTTTAGTAGTTGATATTGACCGAGGAGGTGCTTTTGCTCATATTATTGGTACATTAGAATTACTAGAACCAGAAGAAAG
AAATTTAATCAAAGGAATAGTAATTAACAAATTTAGAGGACAAAGATCTCTCTTAGACTCAGGTATTCACTGGTTAGAAA
AAAAAACTAATATTCCTGTAATAGGTGTCATTCCTTGGATTAATGAAGCCTTTCCCGCAGAAGATTCTTTGAGTATTTTA
GAACAACGTTATAATAAACATACAACTGATATTACAATTGCTATCATTAGATTACCAAGAATTTCTAATTTTACTGATTT
TGAACCTTTAGAAGCAGAGTCTAGTGTCAAAATTAAATATATTCATCCTAATGATAGTTTGGGTGATCCTGATGCCATAA
TTATCCCTGGTACTAAAACTACTATAAACGATTTATTAGTATTACAAAAAAGTGGTATGGCAGAAGCCATCAAATCTTAC
CAAAGTTCTGGTGGTATAGTAATGGGAATTTGTGGTGGATTTCAAATGCTTGGTGAAGTTTTAATTGACTCTCAAGGTTT
AGAAGGAAAACAAGGAGAATATAAAGGATTAGAATTACTACCCTTAATAACTACAATTACTCCTAAAAAAATTGCCAGTC
AGCGACAAGTTATTGCTAATTATCCCTTAGGAAATTTACCAGTCATAGGTTATGAAATTCATCAAGGTAGAACTATAGTT
ACAAAACCAGATATAGTTAAGCCTTTATTTAATGACTATGATTTGGGTTTTGTCGATAGTTATGATTCTATCTGGGGAAA
CTATTTACATGGAATATTTGATAATGGTTCTTGGCGTCGTTCTTGGTTAAATATCCTACGTCACAAACGGGGATTAAACA
GTTTACCAACTAGTATTTCTAATTATAGAGAACAACGAGAAATTATTTTAGATTCAATCGCAGATAAAGTTAATGAGCAT
CTAGATTTAAAACCAGTTTTAACATAA

Upstream 100 bases:

>100_bases
CCTCAACCTTCAATTAGCGATCGCCTGAATAAATTCATAGCTCCTTGGTTTAGAATTCCTCTTTAAACTCTCTCCCTATC
AAACAGAACTAAAAAAAACT

Downstream 100 bases:

>100_bases
AATTTGACAATTACAATAAACGTCAAACCAGTTATTTATTAGTTATCAGTTATCAGTTATTAGTTATAGTAATTGAAGCA
CATATTAAGAAATAATTCTC

Product: cobyric acid synthase

Products: ADP; phosphate; adenosylcobyric acid; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MKAIMVVGTTSHAGKSLITTAICRILSRRGWKVTPFKGQNMALNSYVTSTGGEMGHAQAVQAWAAGVTPAIEMNPILLKP
QGDMTSQVIIKGKASGTVGAVDYYQQYFDIGWNAIQESLETLSQEFNMIVCEGAGSPAEINLKHRDLTNMRVAKHLNAST
ILVVDIDRGGAFAHIIGTLELLEPEERNLIKGIVINKFRGQRSLLDSGIHWLEKKTNIPVIGVIPWINEAFPAEDSLSIL
EQRYNKHTTDITIAIIRLPRISNFTDFEPLEAESSVKIKYIHPNDSLGDPDAIIIPGTKTTINDLLVLQKSGMAEAIKSY
QSSGGIVMGICGGFQMLGEVLIDSQGLEGKQGEYKGLELLPLITTITPKKIASQRQVIANYPLGNLPVIGYEIHQGRTIV
TKPDIVKPLFNDYDLGFVDSYDSIWGNYLHGIFDNGSWRRSWLNILRHKRGLNSLPTSISNYREQREIILDSIADKVNEH
LDLKPVLT

Sequences:

>Translated_488_residues
MKAIMVVGTTSHAGKSLITTAICRILSRRGWKVTPFKGQNMALNSYVTSTGGEMGHAQAVQAWAAGVTPAIEMNPILLKP
QGDMTSQVIIKGKASGTVGAVDYYQQYFDIGWNAIQESLETLSQEFNMIVCEGAGSPAEINLKHRDLTNMRVAKHLNAST
ILVVDIDRGGAFAHIIGTLELLEPEERNLIKGIVINKFRGQRSLLDSGIHWLEKKTNIPVIGVIPWINEAFPAEDSLSIL
EQRYNKHTTDITIAIIRLPRISNFTDFEPLEAESSVKIKYIHPNDSLGDPDAIIIPGTKTTINDLLVLQKSGMAEAIKSY
QSSGGIVMGICGGFQMLGEVLIDSQGLEGKQGEYKGLELLPLITTITPKKIASQRQVIANYPLGNLPVIGYEIHQGRTIV
TKPDIVKPLFNDYDLGFVDSYDSIWGNYLHGIFDNGSWRRSWLNILRHKRGLNSLPTSISNYREQREIILDSIADKVNEH
LDLKPVLT
>Mature_488_residues
MKAIMVVGTTSHAGKSLITTAICRILSRRGWKVTPFKGQNMALNSYVTSTGGEMGHAQAVQAWAAGVTPAIEMNPILLKP
QGDMTSQVIIKGKASGTVGAVDYYQQYFDIGWNAIQESLETLSQEFNMIVCEGAGSPAEINLKHRDLTNMRVAKHLNAST
ILVVDIDRGGAFAHIIGTLELLEPEERNLIKGIVINKFRGQRSLLDSGIHWLEKKTNIPVIGVIPWINEAFPAEDSLSIL
EQRYNKHTTDITIAIIRLPRISNFTDFEPLEAESSVKIKYIHPNDSLGDPDAIIIPGTKTTINDLLVLQKSGMAEAIKSY
QSSGGIVMGICGGFQMLGEVLIDSQGLEGKQGEYKGLELLPLITTITPKKIASQRQVIANYPLGNLPVIGYEIHQGRTIV
TKPDIVKPLFNDYDLGFVDSYDSIWGNYLHGIFDNGSWRRSWLNILRHKRGLNSLPTSISNYREQREIILDSIADKVNEH
LDLKPVLT

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBQ_TRIEI (Q10XP0)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_723457.1
- ProteinModelPortal:   Q10XP0
- STRING:   Q10XP0
- GeneID:   4244040
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_3957
- NMPDR:   fig|203124.1.peg.5089
- eggNOG:   COG1492
- HOGENOM:   HBG302271
- OMA:   AHTDLNP
- ProtClustDB:   PRK00784
- BioCyc:   TERY203124:TERY_3957-MONOMER
- HAMAP:   MF_00028
- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698
- TIGRFAMs:   TIGR00313

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3

EC number: 6.3.5.10

Molecular weight: Translated: 53896; Mature: 53896

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS51274 GATASE_COBBQ

Important sites: ACT_SITE 331-331 ACT_SITE 430-430

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIMVVGTTSHAGKSLITTAICRILSRRGWKVTPFKGQNMALNSYVTSTGGEMGHAQAV
CCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCEEEEHEEECCCCCCCHHHHH
QAWAAGVTPAIEMNPILLKPQGDMTSQVIIKGKASGTVGAVDYYQQYFDIGWNAIQESLE
HHHHCCCCCCEECCCEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHH
TLSQEFNMIVCEGAGSPAEINLKHRDLTNMRVAKHLNASTILVVDIDRGGAFAHIIGTLE
HHHHHCCEEEEECCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCCEEHHHHHHH
LLEPEERNLIKGIVINKFRGQRSLLDSGIHWLEKKTNIPVIGVIPWINEAFPAEDSLSIL
HCCCCHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHH
EQRYNKHTTDITIAIIRLPRISNFTDFEPLEAESSVKIKYIHPNDSLGDPDAIIIPGTKT
HHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCH
TINDLLVLQKSGMAEAIKSYQSSGGIVMGICGGFQMLGEVLIDSQGLEGKQGEYKGLELL
HHHHHHEEECCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCEEEE
PLITTITPKKIASQRQVIANYPLGNLPVIGYEIHQGRTIVTKPDIVKPLFNDYDLGFVDS
EHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEECCHHHHHHHCCCCCCCCCC
YDSIWGNYLHGIFDNGSWRRSWLNILRHKRGLNSLPTSISNYREQREIILDSIADKVNEH
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
LDLKPVLT
CCCCCCCC
>Mature Secondary Structure
MKAIMVVGTTSHAGKSLITTAICRILSRRGWKVTPFKGQNMALNSYVTSTGGEMGHAQAV
CCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCEEEEHEEECCCCCCCHHHHH
QAWAAGVTPAIEMNPILLKPQGDMTSQVIIKGKASGTVGAVDYYQQYFDIGWNAIQESLE
HHHHCCCCCCEECCCEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHH
TLSQEFNMIVCEGAGSPAEINLKHRDLTNMRVAKHLNASTILVVDIDRGGAFAHIIGTLE
HHHHHCCEEEEECCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCCEEHHHHHHH
LLEPEERNLIKGIVINKFRGQRSLLDSGIHWLEKKTNIPVIGVIPWINEAFPAEDSLSIL
HCCCCHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHH
EQRYNKHTTDITIAIIRLPRISNFTDFEPLEAESSVKIKYIHPNDSLGDPDAIIIPGTKT
HHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCH
TINDLLVLQKSGMAEAIKSYQSSGGIVMGICGGFQMLGEVLIDSQGLEGKQGEYKGLELL
HHHHHHEEECCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCEEEE
PLITTITPKKIASQRQVIANYPLGNLPVIGYEIHQGRTIVTKPDIVKPLFNDYDLGFVDS
EHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEECCHHHHHHHCCCCCCCCCC
YDSIWGNYLHGIFDNGSWRRSWLNILRHKRGLNSLPTSISNYREQREIILDSIADKVNEH
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
LDLKPVLT
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; adenosylcobyrinic acid a,c-diamide; L-glutamine; H2O

Specific reaction: 4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA