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The map label for this gene is mtnP [H]

Identifier: 113477159

GI number: 113477159

Start: 5659327

End: 5660199

Strand: Reverse

Name: mtnP [H]

Synonym: Tery_3686

Alternate gene names: 113477159

Gene position: 5660199-5659327 (Counterclockwise)

Preceding gene: 113477160

Following gene: 113477158

Centisome position: 73.03

GC content: 36.66

Gene sequence:

>873_bases
ATGAGCAAAGCAAAGATTGGCATTATTGGCGGTAGTGGTCTGTACAAAATGGAAGCACTCAAAGATGTAGAAGAAATCAA
ACTAGATACACCTTTTGGCTCTCCCTCTGATGCTTTTATTGTTGGTACTCTAGAAGGAATACAAGTAGCATTTCTACCCA
GACACAATCGCAACCATACTTTATTACCATCTGAATTACCGTTTCGTGCTAATATCTATGGTATGAAAAGTTTAGGTGTA
AAATATTTAATCTCTGCTTCTGCAGTTGGTTCTCTCAAAGAAGAAGTCAAGCCACTAGACCTATTAGTAGTAGACCAGTT
CATTGACAGGACAAAAGATCGCATATCTACTTTTTTCGGTGAAGGAATAGTAGCACACATTACTTTTGAAAATCCTACTT
GTCCTGAACTAGCAAAGATACTAGCGGATGCTGCGGAAAGTTTAAAGTTAGAAAATGTAAATGTGCATCGTAGTGGCACT
TATTTATGTATGGAAGGGCCTGCTTTTTCTACTAAAGCGGAGTCAAATTTATATCGCAGTTGGGGTGCAACAGTCATTGG
GATGACAAACTTGCCAGAGGCAAAATTAGCAAGGGAAGCCGAAATAGCTTATGCAACATTAGCTTTGTCTACAGATTATG
ATTGTTGGCATGAAGAACATGATAGCGTGACTGTAGAAATGGTAGTTAATAATTTAAATAAGAATGTGGCGAATGCTCAA
AAAGTTATTCAGGAAACTGTGCGCATATTGAGTAAAAATCAGTTTGTTTCTGATTCTCATTCAGCTTTAAAAGATGCTAT
TTTCACTCCTTTAGATAAAGCACCTACTGCAACTAAGAAAAAGTTGGAATTATTACTGCAGAAATATATTTAA

Upstream 100 bases:

>100_bases
TTTTTTGATTTGTTTTTAACAATTAAAATCACTCCAAAGTAATTTGGCTTCAAATAATACAAGCCTATATCTGGTAAAAT
ATTAGAGTAATAGAAATATA

Downstream 100 bases:

>100_bases
TTTTGAAGGGAGGAGCCAGGACTCAGAACTATTTTGATAAATTTACATTGACTTGTAATAGTGCTCTAGTAAATCAAACC
TTGATTTCCTAGAGAGTCCT

Product: 5'-methylthioadenosine phosphorylase

Products: NA

Alternate protein names: 5'-methylthioadenosine phosphorylase; MTA phosphorylase [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSKAKIGIIGGSGLYKMEALKDVEEIKLDTPFGSPSDAFIVGTLEGIQVAFLPRHNRNHTLLPSELPFRANIYGMKSLGV
KYLISASAVGSLKEEVKPLDLLVVDQFIDRTKDRISTFFGEGIVAHITFENPTCPELAKILADAAESLKLENVNVHRSGT
YLCMEGPAFSTKAESNLYRSWGATVIGMTNLPEAKLAREAEIAYATLALSTDYDCWHEEHDSVTVEMVVNNLNKNVANAQ
KVIQETVRILSKNQFVSDSHSALKDAIFTPLDKAPTATKKKLELLLQKYI

Sequences:

>Translated_290_residues
MSKAKIGIIGGSGLYKMEALKDVEEIKLDTPFGSPSDAFIVGTLEGIQVAFLPRHNRNHTLLPSELPFRANIYGMKSLGV
KYLISASAVGSLKEEVKPLDLLVVDQFIDRTKDRISTFFGEGIVAHITFENPTCPELAKILADAAESLKLENVNVHRSGT
YLCMEGPAFSTKAESNLYRSWGATVIGMTNLPEAKLAREAEIAYATLALSTDYDCWHEEHDSVTVEMVVNNLNKNVANAQ
KVIQETVRILSKNQFVSDSHSALKDAIFTPLDKAPTATKKKLELLLQKYI
>Mature_289_residues
SKAKIGIIGGSGLYKMEALKDVEEIKLDTPFGSPSDAFIVGTLEGIQVAFLPRHNRNHTLLPSELPFRANIYGMKSLGVK
YLISASAVGSLKEEVKPLDLLVVDQFIDRTKDRISTFFGEGIVAHITFENPTCPELAKILADAAESLKLENVNVHRSGTY
LCMEGPAFSTKAESNLYRSWGATVIGMTNLPEAKLAREAEIAYATLALSTDYDCWHEEHDSVTVEMVVNNLNKNVANAQK
VIQETVRILSKNQFVSDSHSALKDAIFTPLDKAPTATKKKLELLLQKYI

Specific function: Catalyzes the formation of methylthio-D-ribose 1- phosphate (MTR-1-P) from methylthioadenosine (MTA) [H]

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=273, Percent_Identity=41.025641025641, Blast_Score=231, Evalue=7e-61,
Organism=Caenorhabditis elegans, GI71980569, Length=254, Percent_Identity=44.4881889763779, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6323045, Length=302, Percent_Identity=38.0794701986755, Blast_Score=197, Evalue=1e-51,
Organism=Drosophila melanogaster, GI20130079, Length=259, Percent_Identity=38.996138996139, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI221459247, Length=260, Percent_Identity=37.3076923076923, Blast_Score=178, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010044
- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.28 [H]

Molecular weight: Translated: 31943; Mature: 31812

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAKIGIIGGSGLYKMEALKDVEEIKLDTPFGSPSDAFIVGTLEGIQVAFLPRHNRNHT
CCCCEEEEEECCCCHHHHHHHHHHHEEEECCCCCCCCEEEEEEECCEEEEEEECCCCCCC
LLPSELPFRANIYGMKSLGVKYLISASAVGSLKEEVKPLDLLVVDQFIDRTKDRISTFFG
CCCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
EGIVAHITFENPTCPELAKILADAAESLKLENVNVHRSGTYLCMEGPAFSTKAESNLYRS
CCEEEEEEECCCCCHHHHHHHHHHHHHCEECCEEEECCCCEEEEECCCCCCHHHHHHHHH
WGATVIGMTNLPEAKLAREAEIAYATLALSTDYDCWHEEHDSVTVEMVVNNLNKNVANAQ
CCCEEEEECCCCHHHHHHHHHHEEEEEEEECCCCHHCCCCCCEEEEHHHHHHCCHHHHHH
KVIQETVRILSKNQFVSDSHSALKDAIFTPLDKAPTATKKKLELLLQKYI
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKAKIGIIGGSGLYKMEALKDVEEIKLDTPFGSPSDAFIVGTLEGIQVAFLPRHNRNHT
CCCEEEEEECCCCHHHHHHHHHHHEEEECCCCCCCCEEEEEEECCEEEEEEECCCCCCC
LLPSELPFRANIYGMKSLGVKYLISASAVGSLKEEVKPLDLLVVDQFIDRTKDRISTFFG
CCCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
EGIVAHITFENPTCPELAKILADAAESLKLENVNVHRSGTYLCMEGPAFSTKAESNLYRS
CCEEEEEEECCCCCHHHHHHHHHHHHHCEECCEEEECCCCEEEEECCCCCCHHHHHHHHH
WGATVIGMTNLPEAKLAREAEIAYATLALSTDYDCWHEEHDSVTVEMVVNNLNKNVANAQ
CCCEEEEECCCCHHHHHHHHHHEEEEEEEECCCCHHCCCCCCEEEEHHHHHHCCHHHHHH
KVIQETVRILSKNQFVSDSHSALKDAIFTPLDKAPTATKKKLELLLQKYI
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA