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The map label for this gene is hemB [H]

Identifier: 113477157

GI number: 113477157

Start: 5658430

End: 5658603

Strand: Reverse

Name: hemB [H]

Synonym: Tery_3684

Alternate gene names: 113477157

Gene position: 5658603-5658430 (Counterclockwise)

Preceding gene: 113477158

Following gene: 113477154

Centisome position: 73.01

GC content: 41.38

Gene sequence:

>174_bases
ATGCCAATGCCAGGGGTATATCAGCTCTCAGTAGATAAAATTGTTGAGGAAGCAAAGGAAGTCTATGACTTGGGAATTCC
TGGAGTTATCTTGTTTGGCATCTCTGATGATAAAGAACTGAAGCTATGGGGACTTTGCATGCAAGGTCCCTACAATTTTT
TGGTTGTGATGTGA

Upstream 100 bases:

>100_bases
TAATCAAAAGGTCATACAACTAGCCTCAAAGATTATGAAAAGCTCTTTGCCTATGAACAGCTCTTTCCGAAAAAAGGAGG
GATACTAAGCATATTGGTTA

Downstream 100 bases:

>100_bases
AGCTCATGGGGTAACAAACTTGTAGGTAGGGCTTTAACTCTAATAAAAACCATCTAGTTTTTTATCCCTTTAATTATATA
CTAATTCCCATGCATTAATG

Product: Delta-aminolevulinic acid dehydratase-like protein

Products: NA

Alternate protein names: ALAD; ALADH; Porphobilinogen synthase [H]

Number of amino acids: Translated: 57; Mature: 56

Protein sequence:

>57_residues
MPMPGVYQLSVDKIVEEAKEVYDLGIPGVILFGISDDKELKLWGLCMQGPYNFLVVM

Sequences:

>Translated_57_residues
MPMPGVYQLSVDKIVEEAKEVYDLGIPGVILFGISDDKELKLWGLCMQGPYNFLVVM
>Mature_56_residues
PMPGVYQLSVDKIVEEAKEVYDLGIPGVILFGISDDKELKLWGLCMQGPYNFLVVM

Specific function: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen [H]

COG id: COG0113

COG function: function code H; Delta-aminolevulinic acid dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ALADH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001731
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00490 ALAD [H]

EC number: =4.2.1.24 [H]

Molecular weight: Translated: 6391; Mature: 6259

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
8.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMPGVYQLSVDKIVEEAKEVYDLGIPGVILFGISDDKELKLWGLCMQGPYNFLVVM
CCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEECCCCEEEEEC
>Mature Secondary Structure 
PMPGVYQLSVDKIVEEAKEVYDLGIPGVILFGISDDKELKLWGLCMQGPYNFLVVM
CCCCEEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8123787 [H]