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The map label for this gene is mre11 [H]

Identifier: 113476483

GI number: 113476483

Start: 4512422

End: 4513705

Strand: Reverse

Name: mre11 [H]

Synonym: Tery_2903

Alternate gene names: 113476483

Gene position: 4513705-4512422 (Counterclockwise)

Preceding gene: 113476484

Following gene: 113476481

Centisome position: 58.24

GC content: 34.27

Gene sequence:

>1284_bases
ATGATTAAAATTATCCATCTTTCTGATATTCATATTGGCAGTGGTTTTTCTCATGGTCGTATCAACCCAGAAACAGGTTT
AAACACTCGCCTGGAAGACTTTATTTCCAGTCTAAAACTTTGTATAGATAAAGCAATTTCCGAACCAGTTGATTTAGTTT
TATTCGGTGGAGATGCTTTTCCAGATGCTACTCCTGCACCATACATAAAACAAGCTTTTGCTGGTGAAATACGCCGTTTA
GTAGATGCTCAAATTCCCATAGTATTATTAGTAGGAAACCATGATCAACATTCCCAAGGCCAAGGAGGTGCAAGTTTAGG
TATTTATCGGACTTTAGGAATACCCGGAGTCGTGGTAGGCGATCGCTTAGAAACTCACAAAATTCAAACTCAAAATGGTT
ATATTCAAATTATTACTTTGCCTTGGTTAACTGCTTCTAGTTTAATGACAAAATCTGAGACCGAAGGTAAATCTATGGGT
CAGGTAAATGAGTCACTAATTCAAAAATTGCGGTTGATATTAGAATCAGAAATTCGGAAATTAAACCCAGAAATACCCAC
GGTACTTTTAGGTCATTTAATGGCAGATAGAGCTAGTTTAGGAGCAGAACGTTTTTTAGCAGTTGGTAAAGGTTTTAATA
TTCCTGTTTCTCTGTTAAACCACCCTTATTTTGATTATGTTGCTTTAGGTCACGTTCACAAACATCAAAATTTGAATAAT
TCTAATAACCCACCAATTATTTATCCCGGAAGTATTGAAAGAGTTGACTTTAGCGAGGAGAAGGAAGAGAAAGGTTTTGT
TTTAGTTGAACTAGAAAAAGGTAAAGCTATATGGAAATTTTGTGCCTTGCCTGTACGAAATTTCCAGACTATTAAAGTTA
ATGTTTCGGAAGTAGAAAATCCACAAACTGAGTTATTAAAAACTATTAGTAAATATCAGATAAAAAATGTAGTAGTTAGA
TTAATTTATCAGTTACGTTCTGAACAGTTAGACTTAATAGATAATAGCATTTTACACCAGGCTTTAAGTGAGGCACATAC
TTATACTATTCAACCAGAATTAGTCAGTCAGTTGGCAAGACCACGTTTACCAGAATTATCAACAGGTAATAGTATTGATC
CTTTACAAGCTTTAAAAACTTATTTAGAAAGTCGCGAAGATATTCAAGATATTCAAGAGGAAATGTTAGAAGCTGCAGAT
AAGTTACTAGTAGACAGAGCAGACTTATCAGAGGAACATTTTGATAGTCAGTTAAGTTTATTTACAAATAGCACGAGAAA
ATGA

Upstream 100 bases:

>100_bases
TTCTAAGTTTTGGGTTAACATCATTCTCATATTTATTATTTGAATACCCCAAAATTTAGTCAAAACTCCAGAAGCTTACC
TACTCCCTAAATAAAATAAA

Downstream 100 bases:

>100_bases
AAAAAATTAAATTCAAGCACAGATTTTTTGATAATATCTATTCTCTATTCTTTAGATATCAATGCCACTAAAAATTATAG
TTATCAGAAATCATCAAATC

Product: nuclease SbcCD subunit D

Products: NA

Alternate protein names: pfMre11 [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MIKIIHLSDIHIGSGFSHGRINPETGLNTRLEDFISSLKLCIDKAISEPVDLVLFGGDAFPDATPAPYIKQAFAGEIRRL
VDAQIPIVLLVGNHDQHSQGQGGASLGIYRTLGIPGVVVGDRLETHKIQTQNGYIQIITLPWLTASSLMTKSETEGKSMG
QVNESLIQKLRLILESEIRKLNPEIPTVLLGHLMADRASLGAERFLAVGKGFNIPVSLLNHPYFDYVALGHVHKHQNLNN
SNNPPIIYPGSIERVDFSEEKEEKGFVLVELEKGKAIWKFCALPVRNFQTIKVNVSEVENPQTELLKTISKYQIKNVVVR
LIYQLRSEQLDLIDNSILHQALSEAHTYTIQPELVSQLARPRLPELSTGNSIDPLQALKTYLESREDIQDIQEEMLEAAD
KLLVDRADLSEEHFDSQLSLFTNSTRK

Sequences:

>Translated_427_residues
MIKIIHLSDIHIGSGFSHGRINPETGLNTRLEDFISSLKLCIDKAISEPVDLVLFGGDAFPDATPAPYIKQAFAGEIRRL
VDAQIPIVLLVGNHDQHSQGQGGASLGIYRTLGIPGVVVGDRLETHKIQTQNGYIQIITLPWLTASSLMTKSETEGKSMG
QVNESLIQKLRLILESEIRKLNPEIPTVLLGHLMADRASLGAERFLAVGKGFNIPVSLLNHPYFDYVALGHVHKHQNLNN
SNNPPIIYPGSIERVDFSEEKEEKGFVLVELEKGKAIWKFCALPVRNFQTIKVNVSEVENPQTELLKTISKYQIKNVVVR
LIYQLRSEQLDLIDNSILHQALSEAHTYTIQPELVSQLARPRLPELSTGNSIDPLQALKTYLESREDIQDIQEEMLEAAD
KLLVDRADLSEEHFDSQLSLFTNSTRK
>Mature_427_residues
MIKIIHLSDIHIGSGFSHGRINPETGLNTRLEDFISSLKLCIDKAISEPVDLVLFGGDAFPDATPAPYIKQAFAGEIRRL
VDAQIPIVLLVGNHDQHSQGQGGASLGIYRTLGIPGVVVGDRLETHKIQTQNGYIQIITLPWLTASSLMTKSETEGKSMG
QVNESLIQKLRLILESEIRKLNPEIPTVLLGHLMADRASLGAERFLAVGKGFNIPVSLLNHPYFDYVALGHVHKHQNLNN
SNNPPIIYPGSIERVDFSEEKEEKGFVLVELEKGKAIWKFCALPVRNFQTIKVNVSEVENPQTELLKTISKYQIKNVVVR
LIYQLRSEQLDLIDNSILHQALSEAHTYTIQPELVSQLARPRLPELSTGNSIDPLQALKTYLESREDIQDIQEEMLEAAD
KLLVDRADLSEEHFDSQLSLFTNSTRK

Specific function: Involved in DNA double-strand break repair (DSBR). The rad50/mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity [H]

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MRE11/RAD32 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003701
- InterPro:   IPR004843
- InterPro:   IPR004593 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 47699; Mature: 47699

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIIHLSDIHIGSGFSHGRINPETGLNTRLEDFISSLKLCIDKAISEPVDLVLFGGDAF
CEEEEEECCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
PDATPAPYIKQAFAGEIRRLVDAQIPIVLLVGNHDQHSQGQGGASLGIYRTLGIPGVVVG
CCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCEEEC
DRLETHKIQTQNGYIQIITLPWLTASSLMTKSETEGKSMGQVNESLIQKLRLILESEIRK
CCCHHCEEECCCCEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LNPEIPTVLLGHLMADRASLGAERFLAVGKGFNIPVSLLNHPYFDYVALGHVHKHQNLNN
CCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCC
SNNPPIIYPGSIERVDFSEEKEEKGFVLVELEKGKAIWKFCALPVRNFQTIKVNVSEVEN
CCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCEEEEEEHHHCCC
PQTELLKTISKYQIKNVVVRLIYQLRSEQLDLIDNSILHQALSEAHTYTIQPELVSQLAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHC
PRLPELSTGNSIDPLQALKTYLESREDIQDIQEEMLEAADKLLVDRADLSEEHFDSQLSL
CCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FTNSTRK
HHCCCCC
>Mature Secondary Structure
MIKIIHLSDIHIGSGFSHGRINPETGLNTRLEDFISSLKLCIDKAISEPVDLVLFGGDAF
CEEEEEECCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
PDATPAPYIKQAFAGEIRRLVDAQIPIVLLVGNHDQHSQGQGGASLGIYRTLGIPGVVVG
CCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCEEEC
DRLETHKIQTQNGYIQIITLPWLTASSLMTKSETEGKSMGQVNESLIQKLRLILESEIRK
CCCHHCEEECCCCEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LNPEIPTVLLGHLMADRASLGAERFLAVGKGFNIPVSLLNHPYFDYVALGHVHKHQNLNN
CCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCC
SNNPPIIYPGSIERVDFSEEKEEKGFVLVELEKGKAIWKFCALPVRNFQTIKVNVSEVEN
CCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCEEEEEEHHHCCC
PQTELLKTISKYQIKNVVVRLIYQLRSEQLDLIDNSILHQALSEAHTYTIQPELVSQLAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHHC
PRLPELSTGNSIDPLQALKTYLESREDIQDIQEEMLEAADKLLVDRADLSEEHFDSQLSL
CCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FTNSTRK
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11029422 [H]