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The map label for this gene is kinB [H]

Identifier: 113476148

GI number: 113476148

Start: 3909899

End: 3911002

Strand: Reverse

Name: kinB [H]

Synonym: Tery_2534

Alternate gene names: 113476148

Gene position: 3911002-3909899 (Counterclockwise)

Preceding gene: 113476155

Following gene: 113476147

Centisome position: 50.46

GC content: 32.7

Gene sequence:

>1104_bases
ATGAAACTAGAAGAACATCAATTTATTCGCTATTTTGGGAAAGATAAAGTTGCCAAAATTTCCCAATTTGCTATTATTAA
AAAATTTAGTCCCCAGGATATTCTTGTTGACCAAGGCAATAATTCAGATGCCTTATTCTTAATTCTCGAAGGTGAAGCTC
TAGTCAGTAAAAAAAGTGAGGAATGTGATAATTATATTATAATTACATCAATTAAATCAAATGATTTTTTTGGCGAATTG
GGAATTATAGATAGACAGCCAAGGAGTTGTAGGGTAGTTGCACTTAGGGAAACAACTGTAGCTCAAATTTACTATGACCA
TATAATCGATATATTAGCTGAAACACAAGGGGATGTTGTTTTAAAGATATTAAGTATTTTATCTCAAAGGCTGCGCAGCA
TAACAACGGAATATGTCAACCAATTAGCTTATAAAGAAAAAATGACTTTAATTGGAGAGATGGTCAACACTATTATTCAT
GATTTTAGAAGCCCTTTTACTGGCATTCAACTATCAAGTTCCATGTTAAAAGAACTCCATCCAGATCAAGAAAGTCAAGA
GTGGTGCGATTTAATTTCTATGCAAGTTCAGAGGATGTTAAATATGGCAGAAGAAGTGCTTGCTTTTTCTCAGGGAAATA
CAAAACTATACTCTCGGCAAGTTGACATAGCCAAGCTATTACAAAACTTTCAAAAATTAAACCAGGTTTATATTGATTCG
ACTTTTGTAGAGTTAATAGTTTCTTTTGAAGAGAGTTTGATCATAAATGCTGATGAAAACAAAATTAACCGTGCCCTACA
AAATTTATTAGCTAATGCTGTAGAAGCTGTAAATAAAGATAAAGGCCAGATAGAAATTAAAGCTAAAAGAAAAGAGCCAT
GGGTTGAAATTACATTCTCGGATAATGGATCTGGTATTCCTGAGGAAATTAAGAATAGTTTATTTAAACCTTTTGTAAGT
TATGGAAAACAGGGTGGTATAGGATTAGGAACTGCTATTGTGAAAACAATTGTTGATGCCCACGGGGGAGAGATTTGTTT
TGAATCAATTATAGGCAAAGGTACAACTTTTTACCTTCGTTTTCCTGTAGCTAAAATAGATTAA

Upstream 100 bases:

>100_bases
TCATAAAAATGTTTTTTTTGACAACAGATATTTTTGACTGTAGATTAATCTATTACAAGTAATAATAGTCAACCTAAAAA
TATACTATATCTCACTACTA

Downstream 100 bases:

>100_bases
ATTATAAAAAAAGAAACATTAATATTTATTGCTAAATTTCGATTGAGAATAAAGTGACTGACAATTTTAACGATAATTTT
ACACCTCCATCTGCTGATAT

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKLEEHQFIRYFGKDKVAKISQFAIIKKFSPQDILVDQGNNSDALFLILEGEALVSKKSEECDNYIIITSIKSNDFFGEL
GIIDRQPRSCRVVALRETTVAQIYYDHIIDILAETQGDVVLKILSILSQRLRSITTEYVNQLAYKEKMTLIGEMVNTIIH
DFRSPFTGIQLSSSMLKELHPDQESQEWCDLISMQVQRMLNMAEEVLAFSQGNTKLYSRQVDIAKLLQNFQKLNQVYIDS
TFVELIVSFEESLIINADENKINRALQNLLANAVEAVNKDKGQIEIKAKRKEPWVEITFSDNGSGIPEEIKNSLFKPFVS
YGKQGGIGLGTAIVKTIVDAHGGEICFESIIGKGTTFYLRFPVAKID

Sequences:

>Translated_367_residues
MKLEEHQFIRYFGKDKVAKISQFAIIKKFSPQDILVDQGNNSDALFLILEGEALVSKKSEECDNYIIITSIKSNDFFGEL
GIIDRQPRSCRVVALRETTVAQIYYDHIIDILAETQGDVVLKILSILSQRLRSITTEYVNQLAYKEKMTLIGEMVNTIIH
DFRSPFTGIQLSSSMLKELHPDQESQEWCDLISMQVQRMLNMAEEVLAFSQGNTKLYSRQVDIAKLLQNFQKLNQVYIDS
TFVELIVSFEESLIINADENKINRALQNLLANAVEAVNKDKGQIEIKAKRKEPWVEITFSDNGSGIPEEIKNSLFKPFVS
YGKQGGIGLGTAIVKTIVDAHGGEICFESIIGKGTTFYLRFPVAKID
>Mature_367_residues
MKLEEHQFIRYFGKDKVAKISQFAIIKKFSPQDILVDQGNNSDALFLILEGEALVSKKSEECDNYIIITSIKSNDFFGEL
GIIDRQPRSCRVVALRETTVAQIYYDHIIDILAETQGDVVLKILSILSQRLRSITTEYVNQLAYKEKMTLIGEMVNTIIH
DFRSPFTGIQLSSSMLKELHPDQESQEWCDLISMQVQRMLNMAEEVLAFSQGNTKLYSRQVDIAKLLQNFQKLNQVYIDS
TFVELIVSFEESLIINADENKINRALQNLLANAVEAVNKDKGQIEIKAKRKEPWVEITFSDNGSGIPEEIKNSLFKPFVS
YGKQGGIGLGTAIVKTIVDAHGGEICFESIIGKGTTFYLRFPVAKID

Specific function: Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. KinB functions as a membrane-associated protein kinase that phosphorylates AlgB, probably in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=273, Percent_Identity=26.3736263736264, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788549, Length=253, Percent_Identity=28.8537549407115, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=28.7610619469027, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786600, Length=219, Percent_Identity=29.6803652968037, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788713, Length=230, Percent_Identity=28.695652173913, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=267, Percent_Identity=25.8426966292135, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790346, Length=244, Percent_Identity=26.2295081967213, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081816, Length=215, Percent_Identity=26.5116279069767, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=231, Percent_Identity=25.974025974026, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=223, Percent_Identity=24.6636771300448, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013656
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF08448 PAS_4 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41506; Mature: 41506

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50042 CNMP_BINDING_3 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEEHQFIRYFGKDKVAKISQFAIIKKFSPQDILVDQGNNSDALFLILEGEALVSKKSE
CCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEEECCHHHHCCHH
ECDNYIIITSIKSNDFFGELGIIDRQPRSCRVVALRETTVAQIYYDHIIDILAETQGDVV
CCCCEEEEEEECCCCCEECCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCHHH
LKILSILSQRLRSITTEYVNQLAYKEKMTLIGEMVNTIIHDFRSPFTGIQLSSSMLKELH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
PDQESQEWCDLISMQVQRMLNMAEEVLAFSQGNTKLYSRQVDIAKLLQNFQKLNQVYIDS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCHHHHHHHHHHHHHHHHHHH
TFVELIVSFEESLIINADENKINRALQNLLANAVEAVNKDKGQIEIKAKRKEPWVEITFS
HHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEC
DNGSGIPEEIKNSLFKPFVSYGKQGGIGLGTAIVKTIVDAHGGEICFESIIGKGTTFYLR
CCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEE
FPVAKID
ECCHHCC
>Mature Secondary Structure
MKLEEHQFIRYFGKDKVAKISQFAIIKKFSPQDILVDQGNNSDALFLILEGEALVSKKSE
CCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEEECCHHHHCCHH
ECDNYIIITSIKSNDFFGELGIIDRQPRSCRVVALRETTVAQIYYDHIIDILAETQGDVV
CCCCEEEEEEECCCCCEECCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCHHH
LKILSILSQRLRSITTEYVNQLAYKEKMTLIGEMVNTIIHDFRSPFTGIQLSSSMLKELH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
PDQESQEWCDLISMQVQRMLNMAEEVLAFSQGNTKLYSRQVDIAKLLQNFQKLNQVYIDS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCHHHHHHHHHHHHHHHHHHH
TFVELIVSFEESLIINADENKINRALQNLLANAVEAVNKDKGQIEIKAKRKEPWVEITFS
HHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEC
DNGSGIPEEIKNSLFKPFVSYGKQGGIGLGTAIVKTIVDAHGGEICFESIIGKGTTFYLR
CCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEE
FPVAKID
ECCHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9218420 [H]