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The map label for this gene is yugF [H]

Identifier: 113475883

GI number: 113475883

Start: 3487893

End: 3488798

Strand: Reverse

Name: yugF [H]

Synonym: Tery_2242

Alternate gene names: 113475883

Gene position: 3488798-3487893 (Counterclockwise)

Preceding gene: 113475885

Following gene: 113475881

Centisome position: 45.02

GC content: 38.52

Gene sequence:

>906_bases
ATGTTGACTAAATCTATAACTACTACAATTTCAGTTCCTGGAAGTTATTGGCTATGGAAGAATCAGCAAATCTACTACTT
ATGTGCAGGTAAGTCTAACCCTACCCATCCACCCTTACTATTAATACATGGCTTTGGAGGCTCTACAGACCATTGGCGCA
AAAATATTGCAGCTCTCAGCGAGTTTTTTCAAGTTTGGGCTATTGACTTATTAGGATTTGGACGTTCAGGTAAACCAAAC
TGGCAATATAGTGGTAAGCTATGGCAACAACAGATCAATGACTTTATTACCCAAGTTATAGGTAGATCAGTAGTCTTAGT
AGGAAATTCTCTTGGAGGTTATGTAGCATTGTGCGTAGCAGCTGAATATCCAACTTCTACAGCAGGTTTGATACTTCTTA
ACAGTGCTGGACCATTTAGCGAATCTCAACCTACTCCTAAGCCCCCAATATTTAGACAATTTATTTCTCGGATCACAAAG
TGGTTATTTCTGCAAACCCTACCTAGTTTTTTATTATTTCAATGGACCCGACGACGTAGCACTATTAGAAAAATATTACA
AAAAGTTTATTTGGATCAAAGTGCTATTACAGACCAATTAATAGAAGATATATATCGACCTTCTTGTGACCCCGGTGCAG
CTCAAGTCTTTGCTTCTATTTTTAAGGCACCATCTGGTAAGAAAGTAGATGAGTTGTTGGGTGACTTAGAGTCTCCTCTA
CTTATGCTTTCGGGAGAAGCTGACCCTTGGATCAATACAAGAAGCCGGAGTGTCCAATTTCGTAAATATTATCCTCAGTT
AACAGAATACTTCTTAAAAGCAGGTCATTGTCCCCATGACGAAGCTCCTGATCTTGTTAATAAGTTAATTCAGGAATGGG
TTTTCTCAACAGTTAAAAGGTTCTAG

Upstream 100 bases:

>100_bases
CATTGACAATATTTATTCTGTAGCAATATAATCTTATTCCATTATATTTTTGATATAGTATTTAATGTAATTTAATAAAC
ATTTAATAAATATTTAATGT

Downstream 100 bases:

>100_bases
GATACGCAATAGGCTTTTATTATTTTCTAATCAGTAAAAACGAGGATGAATTCTGGGGTTGAGCAGATCATCTACAGGTT
TATTGCCCACGAAATGTTGT

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MLTKSITTTISVPGSYWLWKNQQIYYLCAGKSNPTHPPLLLIHGFGGSTDHWRKNIAALSEFFQVWAIDLLGFGRSGKPN
WQYSGKLWQQQINDFITQVIGRSVVLVGNSLGGYVALCVAAEYPTSTAGLILLNSAGPFSESQPTPKPPIFRQFISRITK
WLFLQTLPSFLLFQWTRRRSTIRKILQKVYLDQSAITDQLIEDIYRPSCDPGAAQVFASIFKAPSGKKVDELLGDLESPL
LMLSGEADPWINTRSRSVQFRKYYPQLTEYFLKAGHCPHDEAPDLVNKLIQEWVFSTVKRF

Sequences:

>Translated_301_residues
MLTKSITTTISVPGSYWLWKNQQIYYLCAGKSNPTHPPLLLIHGFGGSTDHWRKNIAALSEFFQVWAIDLLGFGRSGKPN
WQYSGKLWQQQINDFITQVIGRSVVLVGNSLGGYVALCVAAEYPTSTAGLILLNSAGPFSESQPTPKPPIFRQFISRITK
WLFLQTLPSFLLFQWTRRRSTIRKILQKVYLDQSAITDQLIEDIYRPSCDPGAAQVFASIFKAPSGKKVDELLGDLESPL
LMLSGEADPWINTRSRSVQFRKYYPQLTEYFLKAGHCPHDEAPDLVNKLIQEWVFSTVKRF
>Mature_301_residues
MLTKSITTTISVPGSYWLWKNQQIYYLCAGKSNPTHPPLLLIHGFGGSTDHWRKNIAALSEFFQVWAIDLLGFGRSGKPN
WQYSGKLWQQQINDFITQVIGRSVVLVGNSLGGYVALCVAAEYPTSTAGLILLNSAGPFSESQPTPKPPIFRQFISRITK
WLFLQTLPSFLLFQWTRRRSTIRKILQKVYLDQSAITDQLIEDIYRPSCDPGAAQVFASIFKAPSGKKVDELLGDLESPL
LMLSGEADPWINTRSRSVQFRKYYPQLTEYFLKAGHCPHDEAPDLVNKLIQEWVFSTVKRF

Specific function: Not Clear. Seems To Be Implicated In The Early Steps Of Biotin Biosynthesis. [C]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=292, Percent_Identity=26.3698630136986, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32566936, Length=272, Percent_Identity=29.0441176470588, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17558492, Length=272, Percent_Identity=29.0441176470588, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI25146278, Length=298, Percent_Identity=24.8322147651007, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24586385, Length=277, Percent_Identity=22.7436823104693, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24586387, Length=277, Percent_Identity=22.7436823104693, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24586391, Length=277, Percent_Identity=22.7436823104693, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24586389, Length=277, Percent_Identity=22.7436823104693, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 34124; Mature: 34124

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTKSITTTISVPGSYWLWKNQQIYYLCAGKSNPTHPPLLLIHGFGGSTDHWRKNIAALS
CCCCCCEEEEECCCCEEEEECCEEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHH
EFFQVWAIDLLGFGRSGKPNWQYSGKLWQQQINDFITQVIGRSVVLVGNSLGGYVALCVA
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHEEE
AEYPTSTAGLILLNSAGPFSESQPTPKPPIFRQFISRITKWLFLQTLPSFLLFQWTRRRS
CCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIRKILQKVYLDQSAITDQLIEDIYRPSCDPGAAQVFASIFKAPSGKKVDELLGDLESPL
HHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCE
LMLSGEADPWINTRSRSVQFRKYYPQLTEYFLKAGHCPHDEAPDLVNKLIQEWVFSTVKR
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHC
F
C
>Mature Secondary Structure
MLTKSITTTISVPGSYWLWKNQQIYYLCAGKSNPTHPPLLLIHGFGGSTDHWRKNIAALS
CCCCCCEEEEECCCCEEEEECCEEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHH
EFFQVWAIDLLGFGRSGKPNWQYSGKLWQQQINDFITQVIGRSVVLVGNSLGGYVALCVA
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHEEE
AEYPTSTAGLILLNSAGPFSESQPTPKPPIFRQFISRITKWLFLQTLPSFLLFQWTRRRS
CCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIRKILQKVYLDQSAITDQLIEDIYRPSCDPGAAQVFASIFKAPSGKKVDELLGDLESPL
HHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCE
LMLSGEADPWINTRSRSVQFRKYYPQLTEYFLKAGHCPHDEAPDLVNKLIQEWVFSTVKR
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHC
F
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]