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The map label for this gene is rrmA [C]

Identifier: 113474535

GI number: 113474535

Start: 1121932

End: 1122537

Strand: Reverse

Name: rrmA [C]

Synonym: Tery_0686

Alternate gene names: 113474535

Gene position: 1122537-1121932 (Counterclockwise)

Preceding gene: 113474536

Following gene: 113474529

Centisome position: 14.48

GC content: 31.02

Gene sequence:

>606_bases
ATGACAAATAAGACTTCTGTTAAACAAACATTTTTTGACCTTTGGGCACCAAGTTATGATTGGTTATTCCCTTCTATAGT
TTATCAAGCTATACATAAAAGGTTACTGGAATATGTAGATTTATCAAATTCAGCAAATGTACTTGATTTAGGTTGTGGTA
CAGGAAAACTTCTCCATCGTCTTGCTGTTAATTTTCCTACTCTTCAAGGTAATGGTTTAGACTTATCTCCAGAAATGATA
AGTCAAGCTAATAGTCGTAATTGTTATCCACAGCGTTTAAAATTTTTATTAGGAAATGCTGAAGAAATACCTTTTGAAAA
TGATGTATTTGATGCTGTTTTTAACACTATTAGTTTTTTACATTATCCTCATCCCCAACAGGTATTTAATGAAGTGAATA
GAGTGTTACGCCATGGTGGATATTTTTATTTAGTTGATTCCTATTTTAAATGGCAAGATGAATTACAGTATTTGAGTATT
TCTCCTGGTGGTTTGAAACTTTACAGTCCAACAGCTCGTGAAAAATTTGGTAAGGAAGCGGGGTTAAATTTACAAGCTAA
TTATTACTTATTAGGATCAGTATTACTAACAATTTTTACTAAATAA

Upstream 100 bases:

>100_bases
GTTTTATTATTAGCCTAATAAATACTCTATAAATTCCAGTATTTCAAGTCTATAGCTTTTTTATACGTACTAATAACTGA
TAATTAAAAACTGAAATTAT

Downstream 100 bases:

>100_bases
TTGTAAGATTATATATACATAAATTTGGTGTTGCCCGTGAAGTACACCTATCCAGTTTAGGAAGCCATAATAAAATATTT
TTACCATTTACACTGTCCGT

Product: type 11 methyltransferase

Products: S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MTNKTSVKQTFFDLWAPSYDWLFPSIVYQAIHKRLLEYVDLSNSANVLDLGCGTGKLLHRLAVNFPTLQGNGLDLSPEMI
SQANSRNCYPQRLKFLLGNAEEIPFENDVFDAVFNTISFLHYPHPQQVFNEVNRVLRHGGYFYLVDSYFKWQDELQYLSI
SPGGLKLYSPTAREKFGKEAGLNLQANYYLLGSVLLTIFTK

Sequences:

>Translated_201_residues
MTNKTSVKQTFFDLWAPSYDWLFPSIVYQAIHKRLLEYVDLSNSANVLDLGCGTGKLLHRLAVNFPTLQGNGLDLSPEMI
SQANSRNCYPQRLKFLLGNAEEIPFENDVFDAVFNTISFLHYPHPQQVFNEVNRVLRHGGYFYLVDSYFKWQDELQYLSI
SPGGLKLYSPTAREKFGKEAGLNLQANYYLLGSVLLTIFTK
>Mature_200_residues
TNKTSVKQTFFDLWAPSYDWLFPSIVYQAIHKRLLEYVDLSNSANVLDLGCGTGKLLHRLAVNFPTLQGNGLDLSPEMIS
QANSRNCYPQRLKFLLGNAEEIPFENDVFDAVFNTISFLHYPHPQQVFNEVNRVLRHGGYFYLVDSYFKWQDELQYLSIS
PGGLKLYSPTAREKFGKEAGLNLQANYYLLGSVLLTIFTK

Specific function: Specifically Methylates The Guanosine In Position 745 Of 23s rRNA. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To M.jannaschii MJ0638 and MJ1123 and M.tuberculosis Rv2003c [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: 2.1.1.51 [C]

Molecular weight: Translated: 23017; Mature: 22886

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKTSVKQTFFDLWAPSYDWLFPSIVYQAIHKRLLEYVDLSNSANVLDLGCGTGKLLHR
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHH
LAVNFPTLQGNGLDLSPEMISQANSRNCYPQRLKFLLGNAEEIPFENDVFDAVFNTISFL
HHHCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
HYPHPQQVFNEVNRVLRHGGYFYLVDSYFKWQDELQYLSISPGGLKLYSPTAREKFGKEA
CCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHCCEEEEECCCCEEEECCHHHHHCCHHC
GLNLQANYYLLGSVLLTIFTK
CCCEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNKTSVKQTFFDLWAPSYDWLFPSIVYQAIHKRLLEYVDLSNSANVLDLGCGTGKLLHR
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHH
LAVNFPTLQGNGLDLSPEMISQANSRNCYPQRLKFLLGNAEEIPFENDVFDAVFNTISFL
HHHCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
HYPHPQQVFNEVNRVLRHGGYFYLVDSYFKWQDELQYLSISPGGLKLYSPTAREKFGKEA
CCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHCCEEEEECCCCEEEECCHHHHHCCHHC
GLNLQANYYLLGSVLLTIFTK
CCCEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Unidentified protein factor B [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; rRNA [C]

Specific reaction: S-Adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

General reaction: Methyl group transfer [C]

Inhibitor: Mg2+; Unidentified protein factor A1 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]