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The map label for this gene is clpP2 [H]

Identifier: 113474441

GI number: 113474441

Start: 938282

End: 938977

Strand: Reverse

Name: clpP2 [H]

Synonym: Tery_0585

Alternate gene names: 113474441

Gene position: 938977-938282 (Counterclockwise)

Preceding gene: 113474442

Following gene: 113474440

Centisome position: 12.12

GC content: 39.8

Gene sequence:

>696_bases
ATGATGGTTCTATCTCAATATTCTGATAATTTAGTTAATAGTAGTTATAGCAAGTCACAAGTTTATTCCGGCCCTAGTAA
TATTGTGCCAATGGTTGTGGAACAGTCAGGCATGGGAGAGAGGGCTTTTGACTTATACTCACGACTACTTCGGGAAAGAA
TAATTTTTCTGGGAACTCAAGTAGATGAGAATTTGGCAAATACCATCACAGCCCAAATGTTATTCTTGGATGCTGAAGAC
CCAGAAAAAGATATCCAACTATATATAAACTCTCCTGGAGGCTCAGTGACTGCAGGAATGGCTATATACGATACGATGCA
ACAGGTACGACCTGATGTAGTTACAATTTGCTATGGTTTAGCAGCAAGTATGGGGGCTTTTCTTCTATCTGGTGGAGCAA
AAGGTAAGAGAATGTCTCTTCCTAGTTCTAGAATTATGATTCACCAGCCTCTAGGTGGTGCTCAGGGTCAAGCTGTAGAT
ATTGAGATTCAAGCTAAGGAAATCCTTTATCATAAGCGTAAGCTAAATGAATTATTAGCAGAACATACAGGTCAACCTCT
AGAAAAAATAGAGGTTGATACAGAGCGTGACTTTTTTATGTCCGCAGAAGAGGCTAAAAACTATGGCCTGATTGATCAAG
TGATTACTAGACAGAATCTTCCTGTACCAGGAGAGTCTGTCCCTGCAATGCAATAA

Upstream 100 bases:

>100_bases
GATAAGTGTTGGATTACTAAAATTAGTAAAAATACGGCATAATGATATTTAGCTCGAAATATACTGAGCCAAAAATTAAA
ATTGATAAATAAACCAGTTT

Downstream 100 bases:

>100_bases
GAGGCAGTTATGTCTAAATACGACTCCCATCTAAAATGTTCATTCTGTGGCAAGTCTCAAGAGCAGGTTAGGAAATTGAT
AGCTGGACCTGGAGTTTATA

Product: ATP-dependent Clp protease proteolytic subunit ClpP

Products: NA

Alternate protein names: Endopeptidase Clp 2 [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MMVLSQYSDNLVNSSYSKSQVYSGPSNIVPMVVEQSGMGERAFDLYSRLLRERIIFLGTQVDENLANTITAQMLFLDAED
PEKDIQLYINSPGGSVTAGMAIYDTMQQVRPDVVTICYGLAASMGAFLLSGGAKGKRMSLPSSRIMIHQPLGGAQGQAVD
IEIQAKEILYHKRKLNELLAEHTGQPLEKIEVDTERDFFMSAEEAKNYGLIDQVITRQNLPVPGESVPAMQ

Sequences:

>Translated_231_residues
MMVLSQYSDNLVNSSYSKSQVYSGPSNIVPMVVEQSGMGERAFDLYSRLLRERIIFLGTQVDENLANTITAQMLFLDAED
PEKDIQLYINSPGGSVTAGMAIYDTMQQVRPDVVTICYGLAASMGAFLLSGGAKGKRMSLPSSRIMIHQPLGGAQGQAVD
IEIQAKEILYHKRKLNELLAEHTGQPLEKIEVDTERDFFMSAEEAKNYGLIDQVITRQNLPVPGESVPAMQ
>Mature_231_residues
MMVLSQYSDNLVNSSYSKSQVYSGPSNIVPMVVEQSGMGERAFDLYSRLLRERIIFLGTQVDENLANTITAQMLFLDAED
PEKDIQLYINSPGGSVTAGMAIYDTMQQVRPDVVTICYGLAASMGAFLLSGGAKGKRMSLPSSRIMIHQPLGGAQGQAVD
IEIQAKEILYHKRKLNELLAEHTGQPLEKIEVDTERDFFMSAEEAKNYGLIDQVITRQNLPVPGESVPAMQ

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=203, Percent_Identity=53.2019704433498, Blast_Score=220, Evalue=8e-58,
Organism=Escherichia coli, GI1786641, Length=206, Percent_Identity=66.0194174757282, Blast_Score=283, Evalue=9e-78,
Organism=Caenorhabditis elegans, GI17538017, Length=190, Percent_Identity=53.6842105263158, Blast_Score=212, Evalue=1e-55,
Organism=Drosophila melanogaster, GI20129427, Length=189, Percent_Identity=56.0846560846561, Blast_Score=224, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 25452; Mature: 25452

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVLSQYSDNLVNSSYSKSQVYSGPSNIVPMVVEQSGMGERAFDLYSRLLRERIIFLGTQ
CEECCCHHCHHHCCCCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
VDENLANTITAQMLFLDAEDPEKDIQLYINSPGGSVTAGMAIYDTMQQVRPDVVTICYGL
HHHHHHHHHHHHEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
AASMGAFLLSGGAKGKRMSLPSSRIMIHQPLGGAQGQAVDIEIQAKEILYHKRKLNELLA
HHHHHHHHHCCCCCCCEECCCCCEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
EHTGQPLEKIEVDTERDFFMSAEEAKNYGLIDQVITRQNLPVPGESVPAMQ
HHCCCCHHHEECCCCHHHHCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MMVLSQYSDNLVNSSYSKSQVYSGPSNIVPMVVEQSGMGERAFDLYSRLLRERIIFLGTQ
CEECCCHHCHHHCCCCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
VDENLANTITAQMLFLDAEDPEKDIQLYINSPGGSVTAGMAIYDTMQQVRPDVVTICYGL
HHHHHHHHHHHHEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
AASMGAFLLSGGAKGKRMSLPSSRIMIHQPLGGAQGQAVDIEIQAKEILYHKRKLNELLA
HHHHHHHHHCCCCCCCEECCCCCEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
EHTGQPLEKIEVDTERDFFMSAEEAKNYGLIDQVITRQNLPVPGESVPAMQ
HHCCCCHHHEECCCCHHHHCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]