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The map label for this gene is glmS [H]

Identifier: 113474326

GI number: 113474326

Start: 721508

End: 723409

Strand: Direct

Name: glmS [H]

Synonym: Tery_0455

Alternate gene names: 113474326

Gene position: 721508-723409 (Clockwise)

Preceding gene: 113474325

Following gene: 113474327

Centisome position: 9.31

GC content: 38.7

Gene sequence:

>1902_bases
ATGTGTGGAATTGTTGGTTATGTTGGTACACAGTTAGCTACAGAAATTTTACTATCAGGATTAGAAAAACTAGAATATCG
GGGTTATGATTCTGCTGGTGTGGCCACTATTTGTAATGGTCAAGTTAAATCTGTTCGTGCTAAAGGTAAGCTATACAACC
TACGGGAAAAATTGGCAGGAGTGGAAATGTTAGCTAATGTTGGCATTGGTCATACTCGTTGGGCAACTCATGGTAAACCG
GAAGAATATAATGCTCACCCCCATACGGATGATACGGAGCGAGTCGCAGTAGTAGAAAATGGAATTGTAGAAAATTATCG
GGAGTTACGCAAAGAATTGGAAAGTCAGGGGCATAAGTTTGTTTCTGAGACGGATACGGAAGTTATTCCTCATTTAATTG
CAGAATTTTTATCTAATTTTGCGGGAAACGAGAAAGGGAGAACGAAGAACAGGGAAAATTTTTTAGAGGCAGTGCGTCAG
ACTGTGAATAAGTTGGATGGGGCATTTGCGATCGCTGTTGTTTGTGCAGACTATCCGAATGAAATTATTGTTGCTAGACA
GCAAGCACCTATATCTATCGGTTTAGGTCAAGGGGAGTTTTTTTGTGCTTCTGATACTCCTGCTCTTATATCTCATACTC
AAGTTGTTGTCAGTTTGGACAATGGAGAAATGGCACGGTTAACTCCTCTGGGAGTCGAAGTTTATAATTTTGATGGCGAT
CGTATCAATAAACTACCTCGTATTCTTAATTGGAGTCCAAATTTAGTTGACAAAAACATTTTTAAGCATTTTATGCTTAA
GGAAATACATGAGCAACCAAATGTTATTAGGAATTGTTTAGAAACTTATATTAATAGTGATTGGGATGTGAAAAATATTC
AGATTTCTCCTACTAATTTAAACTTGTCGTCATCTTTATATAAAAATTTGGAACAGGTGGAAATTTTTGCCTGTGGTACT
AGTTGGCATGCGAGTTTGATTGGTAAGTATTTATTAGAACAATTAGCAGGAATTTCGACTACGGTAAATTATGCTTCTGA
AGCTCGTTATGCTCCTTCTCCTCTGAGAGCAAATACTCTAACAATTGGTGTTACTCAGTCTGGTGAGACGGCTGATACTT
TGGCAGCTTTAGCAATAGAACAACAGCGTCGTTTAGATAAACCTGTTGAATTCACGTCAAGATTATTAGGAATTACTAAC
CGGGTAGAAAGTTCTATTGCTAGTTTAGTGCATCAAATTATTGATATTCGGGCAGGTGTTGAAATTGGGGTTGCTGCAAC
TAAAACATTTGTGGCACAGGTAATAGCTTTTTATTTTTTAGCTATAGATTTAGGATGGCAACGAAAATATTTATCTGGGG
AAAAAATCGCAGAAATTATTAATGGTTTACAAAAAATTCCGGCACAGATGGAACAGATTTTAGATTCTCAAAATAGTCAA
ATTGAAGATTTTGCTCACCAGTTTAATAACACTCAAGATTTGATTTTTATAGGTAGGGGAATTAATTATCCAATTGCTTT
AGAGGGTGCTTTGAAATTGAAGGAAATTAGTTATATTCATGCGGAGGGATATCCAGCGGGTGAGATGAAACATGGTCCGA
TCGCTTTGTTGGATGATCAAGTACCTGTGGTGGCGATCGCTATGCCTGGTTTGGTTTATGAAAAGGTGCTTTCTAATGCT
CAGGAAGCTAAGGCGAGGGATGCGCAGTTAATTGGGGTGACTCCTGAAAGTACGGAGGTGGATATGTTTGATAATGTGTT
GGCGGTGCCGGCAGTGGATGAGTTGTTGTCGCCGATGTTAACTGTTATTCCTTTGCAGTTGTTAGCTTATCATATTGCTG
CTCATCGTGGTTTGGATGTGGATCAGCCACGGAATTTGGCGAAGTCGGTGACAGTGGAGTAA

Upstream 100 bases:

>100_bases
GTCATAATTCCATAAACATTTAACTTATCCTGTGGAATAAGTAAATTTGAGGGAATATATCTTAAATAGTGATTAAAAAT
TAATAGGAGTAAAAAATTAA

Downstream 100 bases:

>100_bases
TATTTTGTTAATTTGCGTTACTGATGTGGGAGGATAGACATATTCCCTAGTGTAAACGCGCGGGGAATATGTCAACAAAA
CTGGTGTTTTCTTTAAGTGA

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MCGIVGYVGTQLATEILLSGLEKLEYRGYDSAGVATICNGQVKSVRAKGKLYNLREKLAGVEMLANVGIGHTRWATHGKP
EEYNAHPHTDDTERVAVVENGIVENYRELRKELESQGHKFVSETDTEVIPHLIAEFLSNFAGNEKGRTKNRENFLEAVRQ
TVNKLDGAFAIAVVCADYPNEIIVARQQAPISIGLGQGEFFCASDTPALISHTQVVVSLDNGEMARLTPLGVEVYNFDGD
RINKLPRILNWSPNLVDKNIFKHFMLKEIHEQPNVIRNCLETYINSDWDVKNIQISPTNLNLSSSLYKNLEQVEIFACGT
SWHASLIGKYLLEQLAGISTTVNYASEARYAPSPLRANTLTIGVTQSGETADTLAALAIEQQRRLDKPVEFTSRLLGITN
RVESSIASLVHQIIDIRAGVEIGVAATKTFVAQVIAFYFLAIDLGWQRKYLSGEKIAEIINGLQKIPAQMEQILDSQNSQ
IEDFAHQFNNTQDLIFIGRGINYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDDQVPVVAIAMPGLVYEKVLSNA
QEAKARDAQLIGVTPESTEVDMFDNVLAVPAVDELLSPMLTVIPLQLLAYHIAAHRGLDVDQPRNLAKSVTVE

Sequences:

>Translated_633_residues
MCGIVGYVGTQLATEILLSGLEKLEYRGYDSAGVATICNGQVKSVRAKGKLYNLREKLAGVEMLANVGIGHTRWATHGKP
EEYNAHPHTDDTERVAVVENGIVENYRELRKELESQGHKFVSETDTEVIPHLIAEFLSNFAGNEKGRTKNRENFLEAVRQ
TVNKLDGAFAIAVVCADYPNEIIVARQQAPISIGLGQGEFFCASDTPALISHTQVVVSLDNGEMARLTPLGVEVYNFDGD
RINKLPRILNWSPNLVDKNIFKHFMLKEIHEQPNVIRNCLETYINSDWDVKNIQISPTNLNLSSSLYKNLEQVEIFACGT
SWHASLIGKYLLEQLAGISTTVNYASEARYAPSPLRANTLTIGVTQSGETADTLAALAIEQQRRLDKPVEFTSRLLGITN
RVESSIASLVHQIIDIRAGVEIGVAATKTFVAQVIAFYFLAIDLGWQRKYLSGEKIAEIINGLQKIPAQMEQILDSQNSQ
IEDFAHQFNNTQDLIFIGRGINYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDDQVPVVAIAMPGLVYEKVLSNA
QEAKARDAQLIGVTPESTEVDMFDNVLAVPAVDELLSPMLTVIPLQLLAYHIAAHRGLDVDQPRNLAKSVTVE
>Mature_633_residues
MCGIVGYVGTQLATEILLSGLEKLEYRGYDSAGVATICNGQVKSVRAKGKLYNLREKLAGVEMLANVGIGHTRWATHGKP
EEYNAHPHTDDTERVAVVENGIVENYRELRKELESQGHKFVSETDTEVIPHLIAEFLSNFAGNEKGRTKNRENFLEAVRQ
TVNKLDGAFAIAVVCADYPNEIIVARQQAPISIGLGQGEFFCASDTPALISHTQVVVSLDNGEMARLTPLGVEVYNFDGD
RINKLPRILNWSPNLVDKNIFKHFMLKEIHEQPNVIRNCLETYINSDWDVKNIQISPTNLNLSSSLYKNLEQVEIFACGT
SWHASLIGKYLLEQLAGISTTVNYASEARYAPSPLRANTLTIGVTQSGETADTLAALAIEQQRRLDKPVEFTSRLLGITN
RVESSIASLVHQIIDIRAGVEIGVAATKTFVAQVIAFYFLAIDLGWQRKYLSGEKIAEIINGLQKIPAQMEQILDSQNSQ
IEDFAHQFNNTQDLIFIGRGINYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDDQVPVVAIAMPGLVYEKVLSNA
QEAKARDAQLIGVTPESTEVDMFDNVLAVPAVDELLSPMLTVIPLQLLAYHIAAHRGLDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=709, Percent_Identity=34.132581100141, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI205277386, Length=704, Percent_Identity=33.0965909090909, Blast_Score=355, Evalue=9e-98,
Organism=Escherichia coli, GI1790167, Length=636, Percent_Identity=42.7672955974843, Blast_Score=480, Evalue=1e-136,
Organism=Escherichia coli, GI1788651, Length=173, Percent_Identity=29.4797687861272, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17539970, Length=443, Percent_Identity=35.665914221219, Blast_Score=246, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI17532899, Length=443, Percent_Identity=34.5372460496614, Blast_Score=243, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17532897, Length=443, Percent_Identity=34.5372460496614, Blast_Score=242, Evalue=4e-64,
Organism=Saccharomyces cerevisiae, GI6322745, Length=446, Percent_Identity=34.7533632286996, Blast_Score=250, Evalue=4e-67,
Organism=Saccharomyces cerevisiae, GI6323731, Length=452, Percent_Identity=26.5486725663717, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323730, Length=213, Percent_Identity=30.9859154929577, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI21357745, Length=706, Percent_Identity=33.9943342776204, Blast_Score=370, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 69780; Mature: 69780

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGYVGTQLATEILLSGLEKLEYRGYDSAGVATICNGQVKSVRAKGKLYNLREKLAG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHCCHHHHHHHHHHH
VEMLANVGIGHTRWATHGKPEEYNAHPHTDDTERVAVVENGIVENYRELRKELESQGHKF
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHH
VSETDTEVIPHLIAEFLSNFAGNEKGRTKNRENFLEAVRQTVNKLDGAFAIAVVCADYPN
HHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
EIIVARQQAPISIGLGQGEFFCASDTPALISHTQVVVSLDNGEMARLTPLGVEVYNFDGD
CEEEEECCCCEEEECCCCCEEECCCCCHHHCCCEEEEEECCCCEEEEEECCEEEEECCCH
RINKLPRILNWSPNLVDKNIFKHFMLKEIHEQPNVIRNCLETYINSDWDVKNIQISPTNL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEEECCCC
NLSSSLYKNLEQVEIFACGTSWHASLIGKYLLEQLAGISTTVNYASEARYAPSPLRANTL
CCHHHHHCCHHHEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEE
TIGVTQSGETADTLAALAIEQQRRLDKPVEFTSRLLGITNRVESSIASLVHQIIDIRAGV
EEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EIGVAATKTFVAQVIAFYFLAIDLGWQRKYLSGEKIAEIINGLQKIPAQMEQILDSQNSQ
EECHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCH
IEDFAHQFNNTQDLIFIGRGINYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDDQ
HHHHHHHHCCCCEEEEEECCCCCCEEECCCEEEHHEEEEECCCCCCCCCCCCCEEEECCC
VPVVAIAMPGLVYEKVLSNAQEAKARDAQLIGVTPESTEVDMFDNVLAVPAVDELLSPML
CCEEEEECCHHHHHHHHCCHHHHHCCCCEEEECCCCCCCHHHHHCEECCCCHHHHHHHHH
TVIPLQLLAYHIAAHRGLDVDQPRNLAKSVTVE
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MCGIVGYVGTQLATEILLSGLEKLEYRGYDSAGVATICNGQVKSVRAKGKLYNLREKLAG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHCCHHHHHHHHHHH
VEMLANVGIGHTRWATHGKPEEYNAHPHTDDTERVAVVENGIVENYRELRKELESQGHKF
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHH
VSETDTEVIPHLIAEFLSNFAGNEKGRTKNRENFLEAVRQTVNKLDGAFAIAVVCADYPN
HHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
EIIVARQQAPISIGLGQGEFFCASDTPALISHTQVVVSLDNGEMARLTPLGVEVYNFDGD
CEEEEECCCCEEEECCCCCEEECCCCCHHHCCCEEEEEECCCCEEEEEECCEEEEECCCH
RINKLPRILNWSPNLVDKNIFKHFMLKEIHEQPNVIRNCLETYINSDWDVKNIQISPTNL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEEECCCC
NLSSSLYKNLEQVEIFACGTSWHASLIGKYLLEQLAGISTTVNYASEARYAPSPLRANTL
CCHHHHHCCHHHEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEE
TIGVTQSGETADTLAALAIEQQRRLDKPVEFTSRLLGITNRVESSIASLVHQIIDIRAGV
EEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EIGVAATKTFVAQVIAFYFLAIDLGWQRKYLSGEKIAEIINGLQKIPAQMEQILDSQNSQ
EECHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCH
IEDFAHQFNNTQDLIFIGRGINYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDDQ
HHHHHHHHCCCCEEEEEECCCCCCEEECCCEEEHHEEEEECCCCCCCCCCCCCEEEECCC
VPVVAIAMPGLVYEKVLSNAQEAKARDAQLIGVTPESTEVDMFDNVLAVPAVDELLSPML
CCEEEEECCHHHHHHHHCCHHHHHCCCCEEEECCCCCCCHHHHHCEECCCCHHHHHHHHH
TVIPLQLLAYHIAAHRGLDVDQPRNLAKSVTVE
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]