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The map label for this gene is mdtA [H]

Identifier: 110835384

GI number: 110835384

Start: 2863146

End: 2864363

Strand: Reverse

Name: mdtA [H]

Synonym: ABO_2523

Alternate gene names: 110835384

Gene position: 2864363-2863146 (Counterclockwise)

Preceding gene: 110835386

Following gene: 110835383

Centisome position: 91.8

GC content: 56.08

Gene sequence:

>1218_bases
ATGAGGGTGCCTGTCATGTTTCGTTCTTTATTGCTGCCGGGGTTGATTGCCACGGGAATGGCGGCAGGGCTGTTGTCTTT
GCAGGGTTGCTCAGAGCCTGAGTCTGAAAACAAGGTACCTGCCCGCCCGGCGTTGGTAGCCCAGCCTCTCTCGGCGGATC
CTACCCAGGATGTATTTCCCGGAGAAATTCGCGCCCGCTATGAGCCGGAACTGGGCTTCCGTATCGGTGGCAAGATTAGC
CAACGGTTGGTGGATGTGGGGGATCGGGTGAGTGAAGGCACGGTGCTCGCCAAGCTGGATACGGATGATGTGAGTTTGAA
GCTAGATGCTGCCCGTGCCCAGATGGCCTCCGCTCAAGCTGACCACAAGTTGGCCAATAGTGAACTGGAACGCTACCGCG
AACTGATGGAACGCAATGTGATTAGCCGTTCCCAATTTGACTCATTTGAGAGTCGTTATGACGCTAGTGTGGCGCAATTG
CGTCAGGCGCGGGCTAACCTGAATGTGGCTCGTAATCAGGCAGACTATGCCTCGTTGAAAGCTCCCCGTGATGGCGTGAT
AGCACAGCGTTTGGCGGAAGCTGGTCAGGTTGTTGCAGCAGGGCAGGCGGTGTTTGTGCTGGCTGTGGATGGCGACCGTG
AAGTGCGTATTGATCTGCCGGAACAGGATGTAGGCCATTTTAAAATTGGTATGCCGGTGGGCATCGAGTTGTGGTCCCGG
CCCGGTCAAGTGTTCGAAGGAAAAATTCGGGAATTGTCTCCTGCGGCGGACCCTCGCTCGCGAACCTTTGAAGCTCGGGT
TGCTTTTGAGAATACGACGGTCGGCGCAGATCTGGGCCAGTCTGCCCGGGTCTTTGTTAGCGGTGTGGCGAATGCAGATA
TACTCAGTATCCCGCTATCGGCATTGACGGCTGAAGGCGAGGCTACCTATGTGTGGGTGATAAACCCAGATACGGGCCTT
GTGCATAAGGCGCCGGTGGAAGTGGGACCCTACCAGGAACAGATAGTACCAGTGCTGCGGGGTTTGCAGCCGCAGGATTG
GGTTGTCAGTGCAGGCACGCATTTGCTACGTGAAGGGCAAGCTGTGATCCCTGTGGACCGTCAGAATCGCCGGTTAGATC
TGAAGCAAACCGCTTTGGCTTCGCAGCTAGAATCTACCGGAGCTGTAGAATCTAATAGTGAAACCGGTGCGCAGTCAGGT
CCGGACGCGGACCAATAA

Upstream 100 bases:

>100_bases
TTTAATAAAATTACTATACTGCCGAGTATAGCATGCCGGCAAGTTAAGCCCGGCAGAATCTGCATCACAAGCAGAGCCAC
TTAATGAGGTGGGATCAATA

Downstream 100 bases:

>100_bases
GGGGAGTATGACTATGTCGTTCAATCTCTCCGAATGGGCGCTAAAAAACCGAACGCTAGTGCTTTATGCCATTATTTTGC
TCGGCGCCTTGGGGGCCATT

Product: RND efflux membrane fusion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MRVPVMFRSLLLPGLIATGMAAGLLSLQGCSEPESENKVPARPALVAQPLSADPTQDVFPGEIRARYEPELGFRIGGKIS
QRLVDVGDRVSEGTVLAKLDTDDVSLKLDAARAQMASAQADHKLANSELERYRELMERNVISRSQFDSFESRYDASVAQL
RQARANLNVARNQADYASLKAPRDGVIAQRLAEAGQVVAAGQAVFVLAVDGDREVRIDLPEQDVGHFKIGMPVGIELWSR
PGQVFEGKIRELSPAADPRSRTFEARVAFENTTVGADLGQSARVFVSGVANADILSIPLSALTAEGEATYVWVINPDTGL
VHKAPVEVGPYQEQIVPVLRGLQPQDWVVSAGTHLLREGQAVIPVDRQNRRLDLKQTALASQLESTGAVESNSETGAQSG
PDADQ

Sequences:

>Translated_405_residues
MRVPVMFRSLLLPGLIATGMAAGLLSLQGCSEPESENKVPARPALVAQPLSADPTQDVFPGEIRARYEPELGFRIGGKIS
QRLVDVGDRVSEGTVLAKLDTDDVSLKLDAARAQMASAQADHKLANSELERYRELMERNVISRSQFDSFESRYDASVAQL
RQARANLNVARNQADYASLKAPRDGVIAQRLAEAGQVVAAGQAVFVLAVDGDREVRIDLPEQDVGHFKIGMPVGIELWSR
PGQVFEGKIRELSPAADPRSRTFEARVAFENTTVGADLGQSARVFVSGVANADILSIPLSALTAEGEATYVWVINPDTGL
VHKAPVEVGPYQEQIVPVLRGLQPQDWVVSAGTHLLREGQAVIPVDRQNRRLDLKQTALASQLESTGAVESNSETGAQSG
PDADQ
>Mature_405_residues
MRVPVMFRSLLLPGLIATGMAAGLLSLQGCSEPESENKVPARPALVAQPLSADPTQDVFPGEIRARYEPELGFRIGGKIS
QRLVDVGDRVSEGTVLAKLDTDDVSLKLDAARAQMASAQADHKLANSELERYRELMERNVISRSQFDSFESRYDASVAQL
RQARANLNVARNQADYASLKAPRDGVIAQRLAEAGQVVAAGQAVFVLAVDGDREVRIDLPEQDVGHFKIGMPVGIELWSR
PGQVFEGKIRELSPAADPRSRTFEARVAFENTTVGADLGQSARVFVSGVANADILSIPLSALTAEGEATYVWVINPDTGL
VHKAPVEVGPYQEQIVPVLRGLQPQDWVVSAGTHLLREGQAVIPVDRQNRRLDLKQTALASQLESTGAVESNSETGAQSG
PDADQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=319, Percent_Identity=26.3322884012539, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081796, Length=333, Percent_Identity=26.4264264264264, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789929, Length=370, Percent_Identity=23.2432432432432, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43661; Mature: 43661

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVPVMFRSLLLPGLIATGMAAGLLSLQGCSEPESENKVPARPALVAQPLSADPTQDVFP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCC
GEIRARYEPELGFRIGGKISQRLVDVGDRVSEGTVLAKLDTDDVSLKLDAARAQMASAQA
CCCEEEECCCCCEEECCHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHH
DHKLANSELERYRELMERNVISRSQFDSFESRYDASVAQLRQARANLNVARNQADYASLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHCC
APRDGVIAQRLAEAGQVVAAGQAVFVLAVDGDREVRIDLPEQDVGHFKIGMPVGIELWSR
CCCCHHHHHHHHHCCCEEECCCEEEEEEECCCCEEEEECCCCCCCEEEECCCCCHHHHCC
PGQVFEGKIRELSPAADPRSRTFEARVAFENTTVGADLGQSARVFVSGVANADILSIPLS
CCHHHHCHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCEEECCHH
ALTAEGEATYVWVINPDTGLVHKAPVEVGPYQEQIVPVLRGLQPQDWVVSAGTHLLREGQ
HHCCCCCEEEEEEECCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
AVIPVDRQNRRLDLKQTALASQLESTGAVESNSETGAQSGPDADQ
EEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVPVMFRSLLLPGLIATGMAAGLLSLQGCSEPESENKVPARPALVAQPLSADPTQDVFP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCC
GEIRARYEPELGFRIGGKISQRLVDVGDRVSEGTVLAKLDTDDVSLKLDAARAQMASAQA
CCCEEEECCCCCEEECCHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHH
DHKLANSELERYRELMERNVISRSQFDSFESRYDASVAQLRQARANLNVARNQADYASLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHCC
APRDGVIAQRLAEAGQVVAAGQAVFVLAVDGDREVRIDLPEQDVGHFKIGMPVGIELWSR
CCCCHHHHHHHHHCCCEEECCCEEEEEEECCCCEEEEECCCCCCCEEEECCCCCHHHHCC
PGQVFEGKIRELSPAADPRSRTFEARVAFENTTVGADLGQSARVFVSGVANADILSIPLS
CCHHHHCHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCEEECCHH
ALTAEGEATYVWVINPDTGLVHKAPVEVGPYQEQIVPVLRGLQPQDWVVSAGTHLLREGQ
HHCCCCCEEEEEEECCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
AVIPVDRQNRRLDLKQTALASQLESTGAVESNSETGAQSGPDADQ
EEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA