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The map label for this gene is bvgA [H]

Identifier: 110835379

GI number: 110835379

Start: 2856165

End: 2856776

Strand: Reverse

Name: bvgA [H]

Synonym: ABO_2518

Alternate gene names: 110835379

Gene position: 2856776-2856165 (Counterclockwise)

Preceding gene: 110835383

Following gene: 110835377

Centisome position: 91.56

GC content: 54.25

Gene sequence:

>612_bases
TTGAAGATTCTGATTGTTGATGATCATCCGTTATTTGCTGATGCGTTAAGCATTACGCTCAAGAATGCCTATGCTGAGGC
AATGATTACTACCTGCGAGCAGCCAAAATGGTTGCTGGATAATCGTCAATTCTTACCGTTGTATGATCTGGTAATTCTTG
ACCAGACGATGCCGCATCTTGATGGTCTGACCCTGTGGAGCCTGATCGGTCGCCTGGTGGGAGGGGCGAAGGTGCTGGTG
TGCTCTGGCTCTGCCACGGAAGCCACCGTGCGCCGTGCGGTGCAGCTGAAGGTGAATGGTTTCGTGGACAAGAGTGAGTC
CGTGGAACAGATCCTCTTTGCCATCCGGGAGATCATGGCCGGCCGCAGCTACTTTTCTGAATCCTTCCGCTTGATGGCCG
GGGCTGCCCCGGAAGAAGCGCTCACCCTCACCCGTCAGCAGTTGGCCATTCTGACCATGCTCCAGGAAGGTCATGGTAAC
AAGGAAATCGCCCGCCAGCTGTTCGTCAGCGTGAACACCATCAAGACCCACTTGCGACTACTCTACGAAAAACTGGACGT
GCCTAACCGCACCGCCTGTATCGAAAAAGCCCGCCAGATAGGCCTGCTTTAG

Upstream 100 bases:

>100_bases
AGGGAAGGGGGCGTGGCTGATCAATGTGCGGGTCTTTCCCGTGGAAATGTATACCGCTTTTTTATAACCTTATCGGCAGG
GTTGGGATAAGGCTGTACCG

Downstream 100 bases:

>100_bases
CTTTTCTTGGAGGACATCATTTCCTCCAGTTTTGCGGTTAGCGTATCCGCTGCTACCGGTTTGAACAGCACATCAATGTC
CTCCGGCAAGGACTGAATGA

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKILIVDDHPLFADALSITLKNAYAEAMITTCEQPKWLLDNRQFLPLYDLVILDQTMPHLDGLTLWSLIGRLVGGAKVLV
CSGSATEATVRRAVQLKVNGFVDKSESVEQILFAIREIMAGRSYFSESFRLMAGAAPEEALTLTRQQLAILTMLQEGHGN
KEIARQLFVSVNTIKTHLRLLYEKLDVPNRTACIEKARQIGLL

Sequences:

>Translated_203_residues
MKILIVDDHPLFADALSITLKNAYAEAMITTCEQPKWLLDNRQFLPLYDLVILDQTMPHLDGLTLWSLIGRLVGGAKVLV
CSGSATEATVRRAVQLKVNGFVDKSESVEQILFAIREIMAGRSYFSESFRLMAGAAPEEALTLTRQQLAILTMLQEGHGN
KEIARQLFVSVNTIKTHLRLLYEKLDVPNRTACIEKARQIGLL
>Mature_203_residues
MKILIVDDHPLFADALSITLKNAYAEAMITTCEQPKWLLDNRQFLPLYDLVILDQTMPHLDGLTLWSLIGRLVGGAKVLV
CSGSATEATVRRAVQLKVNGFVDKSESVEQILFAIREIMAGRSYFSESFRLMAGAAPEEALTLTRQQLAILTMLQEGHGN
KEIARQLFVSVNTIKTHLRLLYEKLDVPNRTACIEKARQIGLL

Specific function: Member of the two-component regulatory system BvgS/BvgA. Activates the transcription of virulence genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786747, Length=201, Percent_Identity=26.865671641791, Blast_Score=80, Evalue=7e-17,
Organism=Escherichia coli, GI1788521, Length=198, Percent_Identity=28.7878787878788, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788712, Length=189, Percent_Identity=25.3968253968254, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789937, Length=194, Percent_Identity=27.8350515463918, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788222, Length=198, Percent_Identity=22.2222222222222, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787277, Length=108, Percent_Identity=35.1851851851852, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22682; Mature: 22682

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIVDDHPLFADALSITLKNAYAEAMITTCEQPKWLLDNRQFLPLYDLVILDQTMPHL
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHCCCC
DGLTLWSLIGRLVGGAKVLVCSGSATEATVRRAVQLKVNGFVDKSESVEQILFAIREIMA
CCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHH
GRSYFSESFRLMAGAAPEEALTLTRQQLAILTMLQEGHGNKEIARQLFVSVNTIKTHLRL
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LYEKLDVPNRTACIEKARQIGLL
HHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKILIVDDHPLFADALSITLKNAYAEAMITTCEQPKWLLDNRQFLPLYDLVILDQTMPHL
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHCCCC
DGLTLWSLIGRLVGGAKVLVCSGSATEATVRRAVQLKVNGFVDKSESVEQILFAIREIMA
CCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHH
GRSYFSESFRLMAGAAPEEALTLTRQQLAILTMLQEGHGNKEIARQLFVSVNTIKTHLRL
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LYEKLDVPNRTACIEKARQIGLL
HHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]