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The map label for this gene is ucpA [C]

Identifier: 110835265

GI number: 110835265

Start: 2725687

End: 2726439

Strand: Direct

Name: ucpA [C]

Synonym: ABO_2404

Alternate gene names: 110835265

Gene position: 2725687-2726439 (Clockwise)

Preceding gene: 110835264

Following gene: 110835271

Centisome position: 87.36

GC content: 55.11

Gene sequence:

>753_bases
ATGCCGACACGTCAAAACATTCTCATCACTGGCGCCAGCTCAGGGCTTGGCGAAGGCATGGCGCGCCTGTTTGCCGCCAT
GGGCCGCAACTTGGCGTTGTGCGCTCGGCGTATGGATCGGCTGGAAGTGTTGAAGGCCGAGCTGGAAGAAAAACATCCCG
GCATCAAGGTGCTGATTAAGCCGCTGGACGTGAACGACTACGACCAAGTGTTTGCGGTGTTCGATGCTTTCCGTACGGAA
ATGGCCGGCATCGATCGCATCATCGTTAACGCGGGCATGGGCAAGGGCCAACCCTTGGGCACCGGTTATTTCTATGCCAA
CCGGCAAACCGCTGAAACCAACTTTGTTGCTGCCCTGGCCCAGGCCGAAGCGGCCATGGAAATTTTCCGCGCCCAGGACA
GTGGCCACCTGGTAATGATTTCTTCCATTAGCGCCATGCGCGGCATGAAGAAAAATTTGACCACCTATGCGGCCACCAAG
GCCGGCGTGGCCATGCTAGCGGAAGGCCTGCAAATGGAATTACAAGATTCGCCTATCAATGTAACCACTATTTTTCCGGG
TTTTATTCGCACCGAGATCAACGAAAAACTGAAAAACACGCCCTTTATGGTGGACACTGAAACCGGCTGCAAGGCGCTGG
TTAAGGCCATAGAGAAAGAAGGCAAAAATGCCTCCGTACCTAGCTGGCCCTGGGGGCCACTCGGCTTCGCCATGCGCACC
TTGCCGCTAAAAATGGTCGGCAAGATTATGTAG

Upstream 100 bases:

>100_bases
GGCACAAGCATAGCCGAGGGCTACACCGTGAAACCGTGTTTCAATTTTAACTGTTGAGCTTACTTTCATTCGAGCAACAC
GACACCGAGCGGAGAAAACA

Downstream 100 bases:

>100_bases
TAAGCGGCGTGCCACGCTGCAGGCTTTTCGCTTTACCAACGCAAGAGGCCGCGCCAAACATTAGGCGCGGCCTCTTGCGT
ATCACAACGGCAACACGATG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MPTRQNILITGASSGLGEGMARLFAAMGRNLALCARRMDRLEVLKAELEEKHPGIKVLIKPLDVNDYDQVFAVFDAFRTE
MAGIDRIIVNAGMGKGQPLGTGYFYANRQTAETNFVAALAQAEAAMEIFRAQDSGHLVMISSISAMRGMKKNLTTYAATK
AGVAMLAEGLQMELQDSPINVTTIFPGFIRTEINEKLKNTPFMVDTETGCKALVKAIEKEGKNASVPSWPWGPLGFAMRT
LPLKMVGKIM

Sequences:

>Translated_250_residues
MPTRQNILITGASSGLGEGMARLFAAMGRNLALCARRMDRLEVLKAELEEKHPGIKVLIKPLDVNDYDQVFAVFDAFRTE
MAGIDRIIVNAGMGKGQPLGTGYFYANRQTAETNFVAALAQAEAAMEIFRAQDSGHLVMISSISAMRGMKKNLTTYAATK
AGVAMLAEGLQMELQDSPINVTTIFPGFIRTEINEKLKNTPFMVDTETGCKALVKAIEKEGKNASVPSWPWGPLGFAMRT
LPLKMVGKIM
>Mature_249_residues
PTRQNILITGASSGLGEGMARLFAAMGRNLALCARRMDRLEVLKAELEEKHPGIKVLIKPLDVNDYDQVFAVFDAFRTEM
AGIDRIIVNAGMGKGQPLGTGYFYANRQTAETNFVAALAQAEAAMEIFRAQDSGHLVMISSISAMRGMKKNLTTYAATKA
GVAMLAEGLQMELQDSPINVTTIFPGFIRTEINEKLKNTPFMVDTETGCKALVKAIEKEGKNASVPSWPWGPLGFAMRTL
PLKMVGKIM

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=198, Percent_Identity=31.8181818181818, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=29.6875, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI7706318, Length=196, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4503817, Length=254, Percent_Identity=27.1653543307087, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI40807363, Length=215, Percent_Identity=28.3720930232558, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI157739938, Length=188, Percent_Identity=25.531914893617, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI7657478, Length=196, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1790717, Length=193, Percent_Identity=25.9067357512953, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082100, Length=221, Percent_Identity=30.316742081448, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=27.7173913043478, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787335, Length=192, Percent_Identity=26.0416666666667, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17532725, Length=235, Percent_Identity=25.9574468085106, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=235, Percent_Identity=28.0851063829787, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=219, Percent_Identity=31.5068493150685, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI116007236, Length=195, Percent_Identity=34.8717948717949, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI116007238, Length=206, Percent_Identity=32.0388349514563, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21358495, Length=190, Percent_Identity=27.8947368421053, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28571387, Length=194, Percent_Identity=32.9896907216495, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24641232, Length=200, Percent_Identity=30, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI116007234, Length=195, Percent_Identity=30.2564102564103, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24663911, Length=200, Percent_Identity=28, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640442, Length=217, Percent_Identity=26.2672811059908, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364892, Length=230, Percent_Identity=24.7826086956522, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24584744, Length=196, Percent_Identity=29.5918367346939, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28574402, Length=196, Percent_Identity=29.5918367346939, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24648944, Length=192, Percent_Identity=27.6041666666667, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364494, Length=195, Percent_Identity=28.2051282051282, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27250; Mature: 27119

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRQNILITGASSGLGEGMARLFAAMGRNLALCARRMDRLEVLKAELEEKHPGIKVLIK
CCCCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
PLDVNDYDQVFAVFDAFRTEMAGIDRIIVNAGMGKGQPLGTGYFYANRQTAETNFVAALA
ECCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHH
QAEAAMEIFRAQDSGHLVMISSISAMRGMKKNLTTYAATKAGVAMLAEGLQMELQDSPIN
HHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEE
VTTIFPGFIRTEINEKLKNTPFMVDTETGCKALVKAIEKEGKNASVPSWPWGPLGFAMRT
EEEECCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
LPLKMVGKIM
HHHHHHHHCC
>Mature Secondary Structure 
PTRQNILITGASSGLGEGMARLFAAMGRNLALCARRMDRLEVLKAELEEKHPGIKVLIK
CCCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
PLDVNDYDQVFAVFDAFRTEMAGIDRIIVNAGMGKGQPLGTGYFYANRQTAETNFVAALA
ECCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHH
QAEAAMEIFRAQDSGHLVMISSISAMRGMKKNLTTYAATKAGVAMLAEGLQMELQDSPIN
HHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEE
VTTIFPGFIRTEINEKLKNTPFMVDTETGCKALVKAIEKEGKNASVPSWPWGPLGFAMRT
EEEECCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
LPLKMVGKIM
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]