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The map label for this gene is speA [H]

Identifier: 110835259

GI number: 110835259

Start: 2719194

End: 2721074

Strand: Reverse

Name: speA [H]

Synonym: ABO_2398

Alternate gene names: 110835259

Gene position: 2721074-2719194 (Counterclockwise)

Preceding gene: 110835261

Following gene: 110835258

Centisome position: 87.21

GC content: 60.87

Gene sequence:

>1881_bases
ATGACCGATAACTCTCCCGTACCCGCCAGCGATATCTATAACGTGGATCGTTGGGGCGACAGTTACTTCCGTATCGACGG
CCAGGGCCAGCTGTGTGTGCGCCCCAATGGCGAGCAAGGCGGCCAAGCCACGCTGGAAGCGGTGCTGGAACGCTGCCGGG
CGGCTGGCCTGCGGGCGCCGGTGCTGGCGCGCTTCTCTGGCATTTTGCGCCAACGGGTGAAGCTGCTGGCGGGCGCCTTT
CGGGAGGCTATCGAGGGGCACCAGTATCAGGGTGACTACACGCCGGTGTACCCGATTAAGGTGAACCAGCAGCGCCGGGT
GGTGCACGAAATCCTCCGTGCCCGCGATGACGGCGAGCGGGTAGGGCTGGAAGCCGGTTCCAAGCCCGAGTTGTTGGCGG
TGCTGGCATTGTCCAACCCCGGCGACACCATTGTCTGCAATGGCTACAAGGATGCGGAATACCTGCGTTTGGCGTTGATG
GGCGAAAAGCTGGGGTTCCATGTGCAGATCGTGGTGGAAAAAACCTCCGAGCTGCCGGCGCTGCTGGCACTGGCCGATGA
ACTGGGGGTGTCGCCGCGCATTGGCCTGCGGGTACGGCTGATGAGTATCAGCAAGGGTAACTGGCAGAACACCGGCGGTG
AAAAATCCAAGTTTGGTTTGAGTGCGCCGCAGCTGATGGCGGCCATTGAGCATTGCCGCGCCGCCGGGCGGCTGGACTGC
GTGAAGCTGCTGCATTTTCACTTGGGCTCCCAGGTGGCCAATATTCAGGATATTAAAGCGGGCATGCGCGAAGCGGCCCG
TTACTACACCGAGATGCGCGCCTTGGGCGCGGCGGTGGAAACCGTGGATGTGGGCGGCGGCCTGGGGGTGGACTATGAAG
GCACCCATTCTCGTTCTTACTGCTCCATGAATTATGGGGTGGCCGATTACGCCCGCCATATTGTGCAGACCCTGCAACAG
CAATGTGCGGAGCACGGCGTGCCGGAGCCGCATATTATTTCCGAATCCGGCCGCGCGCTGACCGCCCACCATGCAGTGTT
GCTGGTGAATATCACCGACCAGGAACAGATGGCGCCGGTGGCGGTGGATGCACCCACCGAGCATGATGCGCCGGAGCTGC
AGCAGCTGTGGGGCCTGCAACAGGTGTTGGCCGGCGAGCCGGGCAACCTGCTGGAGCGTTTCTCGGAAGTGGCCGGCGCC
TGGCAGGATATTCACCAGCGCTATATTGCAGGCGAGTTAGGGCTGGCGGCGCGGGCGCGGGGCGAGCAGTTATACATCAA
CTGCCTGCTGGCGTTGCGTGGCCGCCTGAATCCGTTGCGCAAACAGCAGCGGGCGCTGCTGGATAGCCTTAACGAAACCC
TGGCGGACAAGTTGTTCGTGAATTTCTCAGTGTTCCAATCGGTGCCGGATGTGTGGGGCATTAATCAGGTGTTCCCGGTG
TTGCCGCTCTCCGGTTTGGATAAACCGGCGACCCGCCGTGCGGTGATTCAGGACATTACCTGTGATTCCGATGGCCGCAT
CGACCAGTTTGTGGATGGTGAAGGGGTGGAAGCCACCCTGCCGCTGCCGGAACAGCTCAACGGCCACCTGGGCATTTTTA
TGGTGGGCGCTTACCAGGAAATCCTTGGCGACATGCATAACCTGTTCGGGGATACGGATTCCGTGGATGTGGATGTGGAT
GCGCAGGGCAATATCGTGCTGGACCACGCCATTCAAGGCGATACGGTGAGCTCGGTGTTACGCTACGTGAATTACGACCC
GGACCGGCTATTGGCGTCTTTGGAGCAGCATTGTCGCCAAGCGCATTTAAGCGCAGCGGAACAAGATGGCTTCATCGAAC
TGGTACGCGAAGGGTTGGGCGGGTATACCTATTTGGAATGA

Upstream 100 bases:

>100_bases
AATGGGTGCTAGCGCGGCCTTCCGGCAGGCATAATGGCGACCATTAACCGCATGATGGCCTGCCCGCGTGTTGCGTGCAG
GCGTTTTTTCAGGACCCGCA

Downstream 100 bases:

>100_bases
ATGAGTTGAACGTTCAACTCATTACTGATTCTCAGCCAGCAAGGAGACCACCATGCGTTATGAACTCTGTGCCAGCCAAG
ATTTACCGGAAGGACAAAGC

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 626; Mature: 625

Protein sequence:

>626_residues
MTDNSPVPASDIYNVDRWGDSYFRIDGQGQLCVRPNGEQGGQATLEAVLERCRAAGLRAPVLARFSGILRQRVKLLAGAF
REAIEGHQYQGDYTPVYPIKVNQQRRVVHEILRARDDGERVGLEAGSKPELLAVLALSNPGDTIVCNGYKDAEYLRLALM
GEKLGFHVQIVVEKTSELPALLALADELGVSPRIGLRVRLMSISKGNWQNTGGEKSKFGLSAPQLMAAIEHCRAAGRLDC
VKLLHFHLGSQVANIQDIKAGMREAARYYTEMRALGAAVETVDVGGGLGVDYEGTHSRSYCSMNYGVADYARHIVQTLQQ
QCAEHGVPEPHIISESGRALTAHHAVLLVNITDQEQMAPVAVDAPTEHDAPELQQLWGLQQVLAGEPGNLLERFSEVAGA
WQDIHQRYIAGELGLAARARGEQLYINCLLALRGRLNPLRKQQRALLDSLNETLADKLFVNFSVFQSVPDVWGINQVFPV
LPLSGLDKPATRRAVIQDITCDSDGRIDQFVDGEGVEATLPLPEQLNGHLGIFMVGAYQEILGDMHNLFGDTDSVDVDVD
AQGNIVLDHAIQGDTVSSVLRYVNYDPDRLLASLEQHCRQAHLSAAEQDGFIELVREGLGGYTYLE

Sequences:

>Translated_626_residues
MTDNSPVPASDIYNVDRWGDSYFRIDGQGQLCVRPNGEQGGQATLEAVLERCRAAGLRAPVLARFSGILRQRVKLLAGAF
REAIEGHQYQGDYTPVYPIKVNQQRRVVHEILRARDDGERVGLEAGSKPELLAVLALSNPGDTIVCNGYKDAEYLRLALM
GEKLGFHVQIVVEKTSELPALLALADELGVSPRIGLRVRLMSISKGNWQNTGGEKSKFGLSAPQLMAAIEHCRAAGRLDC
VKLLHFHLGSQVANIQDIKAGMREAARYYTEMRALGAAVETVDVGGGLGVDYEGTHSRSYCSMNYGVADYARHIVQTLQQ
QCAEHGVPEPHIISESGRALTAHHAVLLVNITDQEQMAPVAVDAPTEHDAPELQQLWGLQQVLAGEPGNLLERFSEVAGA
WQDIHQRYIAGELGLAARARGEQLYINCLLALRGRLNPLRKQQRALLDSLNETLADKLFVNFSVFQSVPDVWGINQVFPV
LPLSGLDKPATRRAVIQDITCDSDGRIDQFVDGEGVEATLPLPEQLNGHLGIFMVGAYQEILGDMHNLFGDTDSVDVDVD
AQGNIVLDHAIQGDTVSSVLRYVNYDPDRLLASLEQHCRQAHLSAAEQDGFIELVREGLGGYTYLE
>Mature_625_residues
TDNSPVPASDIYNVDRWGDSYFRIDGQGQLCVRPNGEQGGQATLEAVLERCRAAGLRAPVLARFSGILRQRVKLLAGAFR
EAIEGHQYQGDYTPVYPIKVNQQRRVVHEILRARDDGERVGLEAGSKPELLAVLALSNPGDTIVCNGYKDAEYLRLALMG
EKLGFHVQIVVEKTSELPALLALADELGVSPRIGLRVRLMSISKGNWQNTGGEKSKFGLSAPQLMAAIEHCRAAGRLDCV
KLLHFHLGSQVANIQDIKAGMREAARYYTEMRALGAAVETVDVGGGLGVDYEGTHSRSYCSMNYGVADYARHIVQTLQQQ
CAEHGVPEPHIISESGRALTAHHAVLLVNITDQEQMAPVAVDAPTEHDAPELQQLWGLQQVLAGEPGNLLERFSEVAGAW
QDIHQRYIAGELGLAARARGEQLYINCLLALRGRLNPLRKQQRALLDSLNETLADKLFVNFSVFQSVPDVWGINQVFPVL
PLSGLDKPATRRAVIQDITCDSDGRIDQFVDGEGVEATLPLPEQLNGHLGIFMVGAYQEILGDMHNLFGDTDSVDVDVDA
QGNIVLDHAIQGDTVSSVLRYVNYDPDRLLASLEQHCRQAHLSAAEQDGFIELVREGLGGYTYLE

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=623, Percent_Identity=48.6356340288925, Blast_Score=580, Evalue=1e-166,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 68589; Mature: 68457

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNSPVPASDIYNVDRWGDSYFRIDGQGQLCVRPNGEQGGQATLEAVLERCRAAGLRAP
CCCCCCCCHHHCCCCCCCCCCEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCH
VLARFSGILRQRVKLLAGAFREAIEGHQYQGDYTPVYPIKVNQQRRVVHEILRARDDGER
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCE
VGLEAGSKPELLAVLALSNPGDTIVCNGYKDAEYLRLALMGEKLGFHVQIVVEKTSELPA
ECCCCCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCHH
LLALADELGVSPRIGLRVRLMSISKGNWQNTGGEKSKFGLSAPQLMAAIEHCRAAGRLDC
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHH
VKLLHFHLGSQVANIQDIKAGMREAARYYTEMRALGAAVETVDVGGGLGVDYEGTHSRSY
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCE
CSMNYGVADYARHIVQTLQQQCAEHGVPEPHIISESGRALTAHHAVLLVNITDQEQMAPV
EEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEEEEEEEEECCHHHCCCE
AVDAPTEHDAPELQQLWGLQQVLAGEPGNLLERFSEVAGAWQDIHQRYIAGELGLAARAR
EECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC
GEQLYINCLLALRGRLNPLRKQQRALLDSLNETLADKLFVNFSVFQSVPDVWGINQVFPV
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHC
LPLSGLDKPATRRAVIQDITCDSDGRIDQFVDGEGVEATLPLPEQLNGHLGIFMVGAYQE
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCHHHCCCCEEEEEEHHHHH
ILGDMHNLFGDTDSVDVDVDAQGNIVLDHAIQGDTVSSVLRYVNYDPDRLLASLEQHCRQ
HHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
AHLSAAEQDGFIELVREGLGGYTYLE
HHHHHHCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TDNSPVPASDIYNVDRWGDSYFRIDGQGQLCVRPNGEQGGQATLEAVLERCRAAGLRAP
CCCCCCCHHHCCCCCCCCCCEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCH
VLARFSGILRQRVKLLAGAFREAIEGHQYQGDYTPVYPIKVNQQRRVVHEILRARDDGER
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCE
VGLEAGSKPELLAVLALSNPGDTIVCNGYKDAEYLRLALMGEKLGFHVQIVVEKTSELPA
ECCCCCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCHH
LLALADELGVSPRIGLRVRLMSISKGNWQNTGGEKSKFGLSAPQLMAAIEHCRAAGRLDC
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHH
VKLLHFHLGSQVANIQDIKAGMREAARYYTEMRALGAAVETVDVGGGLGVDYEGTHSRSY
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCE
CSMNYGVADYARHIVQTLQQQCAEHGVPEPHIISESGRALTAHHAVLLVNITDQEQMAPV
EEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEEEEEEEEECCHHHCCCE
AVDAPTEHDAPELQQLWGLQQVLAGEPGNLLERFSEVAGAWQDIHQRYIAGELGLAARAR
EECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC
GEQLYINCLLALRGRLNPLRKQQRALLDSLNETLADKLFVNFSVFQSVPDVWGINQVFPV
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHC
LPLSGLDKPATRRAVIQDITCDSDGRIDQFVDGEGVEATLPLPEQLNGHLGIFMVGAYQE
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCHHHCCCCEEEEEEHHHHH
ILGDMHNLFGDTDSVDVDVDAQGNIVLDHAIQGDTVSSVLRYVNYDPDRLLASLEQHCRQ
HHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
AHLSAAEQDGFIELVREGLGGYTYLE
HHHHHHCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA