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The map label for this gene is 110835254

Identifier: 110835254

GI number: 110835254

Start: 2715498

End: 2717027

Strand: Reverse

Name: 110835254

Synonym: ABO_2393

Alternate gene names: NA

Gene position: 2717027-2715498 (Counterclockwise)

Preceding gene: 110835255

Following gene: 110835252

Centisome position: 87.08

GC content: 53.59

Gene sequence:

>1530_bases
ATGGCCGCAGCAAAAAAAACCAAACCCTCAGCGGCCAAGGGCCCTGCGGAAAAAATTTATGATTCGTTTATTGTCGGTGC
CGGTATCTCCGGTATTGCCGCCGCGATCAAGCTGAAGAAAGAAGGCTATAACAATTTCAAAATCATCGAGCGAGCGGACC
GAGTGGGAGGCACCTGGCGGGAAAATACCTACCCCGGCTGTGGTTGTGATGTGCCGTCATCGTTGTATTCCTATTCATTT
GCGTTGAGCAGCAAGTGGAGCCACCTGTTTGCTAAGCAGCCTGAAATTCTCAGCTACTTGGAAGAGGTGAGTGACAATTT
TGATATTACGCCGCTGATTGAATTCAATACGAATTTGCAGAGCGCGACCTGGGATGAAAGTCGTTACCTTTGGGTGTTGG
GAACCTCTAACGGAGAGCACTTGGCGCGGACGGTGGTTTTTGCCACCGGGCCGATTACCGAATCCAAGACCCCTGTGCTC
CCTGGGCTGGAAAGCTTCAGCGGGGAAATGTTCCATTCCGCCAAGTGGAACCACGATTACGACCTGACCGGGAAACGGGT
GGCGGTGATCGGTACTGGCGCGTCAGCCATTCAATTCGTGCCGCAGATTCAGCCCAAGGTGAAAGAGTTGTTTGTGTTCC
AGCGCACGGCGCCTTGGGTGCTGCCCAAGCCGGACCTGCCACTGGGGGATAGAGTCAAACAGACGATTGAAGTGCTGCCG
GTGATTCAGCGTGGCTGGCGCAATGCGGTGTCCAGATCGCTGAATGTGATTAACTTTGGCCTGCGTAACCCTAAGGTGTT
GAGGCCCATTAGTACTGCAGCAAAACAGCTGCTACGGCTACAGATTAGTGACAAGGCCTTGCGCAAGGCGGTAACGCCGG
ACTTTACCCTGGGCTGCAAGCGCGTGCTGTTCGCCAATGATTACTACCCGGCTTTGCAGGCAGACAATACCCACCTGATT
CCCCACGGGTTGGTAGAAGTGGATGGCAATACTGTGGTCGCGGCCAACGGTGAACGCCATGAAGTGGATGTGATTATCTG
GGGTACCGGCTTTGAAGTGTCGCACCCGCCGATTGGCAGCAAGGTGGTGAATGCCAATGGTGATCGCCTGTCGGACCTTT
GGAAAGACACGTCGCCGGAAGCGTATCTGGGCGCGGCCTTGGAAAATACGCCCAATGCGTTTTTGGTGCTGGGCCCCAAC
GTTTTGGTCTACGACTCCTTTATCGGGCTGGCCGAGGCGCAGCTGGATTACATTATCGATGGCCTGAAAAAAGTGAAGGA
CAACGATATTGGCAAAATCTCCATTCGCTCTGATGTGCTCAGACAGCATAACGCCAAGGTGCAAAAACACTTGAAAGGCA
CGGTGTTTAATAGTGGTGGCTGCAAGAGCTATTACCTGGACCAGAACGGCCGCAACTTCGCCGCCTGGCCTTGGTCATTG
GCCGAATTGAAGCGACGGCTGAGTGTGTTTGATCTTGATGATTATGACGTGACGTACCGTAATGAAGCGGTGTTGAGCAA
GGTGTCCTGA

Upstream 100 bases:

>100_bases
GACGCCAAACTGTTTTGGATAATGAAGCGGGCGTCGCCCCGTCTTTACGCCAAGTTCATGAGTTTCTCTTACCGCTTTGT
TCGCACCAAGGAGGCATAAC

Downstream 100 bases:

>100_bases
ATACGGTACGGATAAATAAAAGCGCACGGTTTTAGGGCCGTGCGTTTTTTTTTGCCAAAACGATTCTCGGTGTGGAGTCG
GATGACGGCCTTCGGCCTAA

Product: monooxygenase flavin-binding family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MAAAKKTKPSAAKGPAEKIYDSFIVGAGISGIAAAIKLKKEGYNNFKIIERADRVGGTWRENTYPGCGCDVPSSLYSYSF
ALSSKWSHLFAKQPEILSYLEEVSDNFDITPLIEFNTNLQSATWDESRYLWVLGTSNGEHLARTVVFATGPITESKTPVL
PGLESFSGEMFHSAKWNHDYDLTGKRVAVIGTGASAIQFVPQIQPKVKELFVFQRTAPWVLPKPDLPLGDRVKQTIEVLP
VIQRGWRNAVSRSLNVINFGLRNPKVLRPISTAAKQLLRLQISDKALRKAVTPDFTLGCKRVLFANDYYPALQADNTHLI
PHGLVEVDGNTVVAANGERHEVDVIIWGTGFEVSHPPIGSKVVNANGDRLSDLWKDTSPEAYLGAALENTPNAFLVLGPN
VLVYDSFIGLAEAQLDYIIDGLKKVKDNDIGKISIRSDVLRQHNAKVQKHLKGTVFNSGGCKSYYLDQNGRNFAAWPWSL
AELKRRLSVFDLDDYDVTYRNEAVLSKVS

Sequences:

>Translated_509_residues
MAAAKKTKPSAAKGPAEKIYDSFIVGAGISGIAAAIKLKKEGYNNFKIIERADRVGGTWRENTYPGCGCDVPSSLYSYSF
ALSSKWSHLFAKQPEILSYLEEVSDNFDITPLIEFNTNLQSATWDESRYLWVLGTSNGEHLARTVVFATGPITESKTPVL
PGLESFSGEMFHSAKWNHDYDLTGKRVAVIGTGASAIQFVPQIQPKVKELFVFQRTAPWVLPKPDLPLGDRVKQTIEVLP
VIQRGWRNAVSRSLNVINFGLRNPKVLRPISTAAKQLLRLQISDKALRKAVTPDFTLGCKRVLFANDYYPALQADNTHLI
PHGLVEVDGNTVVAANGERHEVDVIIWGTGFEVSHPPIGSKVVNANGDRLSDLWKDTSPEAYLGAALENTPNAFLVLGPN
VLVYDSFIGLAEAQLDYIIDGLKKVKDNDIGKISIRSDVLRQHNAKVQKHLKGTVFNSGGCKSYYLDQNGRNFAAWPWSL
AELKRRLSVFDLDDYDVTYRNEAVLSKVS
>Mature_508_residues
AAAKKTKPSAAKGPAEKIYDSFIVGAGISGIAAAIKLKKEGYNNFKIIERADRVGGTWRENTYPGCGCDVPSSLYSYSFA
LSSKWSHLFAKQPEILSYLEEVSDNFDITPLIEFNTNLQSATWDESRYLWVLGTSNGEHLARTVVFATGPITESKTPVLP
GLESFSGEMFHSAKWNHDYDLTGKRVAVIGTGASAIQFVPQIQPKVKELFVFQRTAPWVLPKPDLPLGDRVKQTIEVLPV
IQRGWRNAVSRSLNVINFGLRNPKVLRPISTAAKQLLRLQISDKALRKAVTPDFTLGCKRVLFANDYYPALQADNTHLIP
HGLVEVDGNTVVAANGERHEVDVIIWGTGFEVSHPPIGSKVVNANGDRLSDLWKDTSPEAYLGAALENTPNAFLVLGPNV
LVYDSFIGLAEAQLDYIIDGLKKVKDNDIGKISIRSDVLRQHNAKVQKHLKGTVFNSGGCKSYYLDQNGRNFAAWPWSLA
ELKRRLSVFDLDDYDVTYRNEAVLSKVS

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503755, Length=388, Percent_Identity=23.9690721649485, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI4503757, Length=394, Percent_Identity=23.8578680203046, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI221316674, Length=365, Percent_Identity=24.9315068493151, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI221316672, Length=365, Percent_Identity=24.9315068493151, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4503759, Length=361, Percent_Identity=23.8227146814404, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI221316678, Length=219, Percent_Identity=27.8538812785388, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193202226, Length=232, Percent_Identity=30.1724137931034, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 56296; Mature: 56164

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAKKTKPSAAKGPAEKIYDSFIVGAGISGIAAAIKLKKEGYNNFKIIERADRVGGTWR
CCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHEEECCCCCCCEEEEEHHHHCCCCCC
ENTYPGCGCDVPSSLYSYSFALSSKWSHLFAKQPEILSYLEEVSDNFDITPLIEFNTNLQ
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCC
SATWDESRYLWVLGTSNGEHLARTVVFATGPITESKTPVLPGLESFSGEMFHSAKWNHDY
CCCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHCCCHHCCCCCCCCC
DLTGKRVAVIGTGASAIQFVPQIQPKVKELFVFQRTAPWVLPKPDLPLGDRVKQTIEVLP
CCCCCEEEEEECCHHHHHHHHCCCHHHHHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
VIQRGWRNAVSRSLNVINFGLRNPKVLRPISTAAKQLLRLQISDKALRKAVTPDFTLGCK
HHHHHHHHHHHHCCEEEEECCCCCCEECHHHHHHHHHHHHHHCHHHHHHHCCCCHHHCCE
RVLFANDYYPALQADNTHLIPHGLVEVDGNTVVAANGERHEVDVIIWGTGFEVSHPPIGS
EEEEECCCCCCEECCCCEECCCCEEEECCCEEEEECCCCEEEEEEEEECCCCCCCCCCCC
KVVNANGDRLSDLWKDTSPEAYLGAALENTPNAFLVLGPNVLVYDSFIGLAEAQLDYIID
EEECCCCCHHHHHHCCCCCCCEEEHHHCCCCCEEEEECCCEEEEECHHHHHHHHHHHHHH
GLKKVKDNDIGKISIRSDVLRQHNAKVQKHLKGTVFNSGGCKSYYLDQNGRNFAAWPWSL
HHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCEEECCCCCEEEEECCCCCEEEECCCHH
AELKRRLSVFDLDDYDVTYRNEAVLSKVS
HHHHHHCCEEECCCCCEEECCHHHHHCCC
>Mature Secondary Structure 
AAAKKTKPSAAKGPAEKIYDSFIVGAGISGIAAAIKLKKEGYNNFKIIERADRVGGTWR
CCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHEEECCCCCCCEEEEEHHHHCCCCCC
ENTYPGCGCDVPSSLYSYSFALSSKWSHLFAKQPEILSYLEEVSDNFDITPLIEFNTNLQ
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCC
SATWDESRYLWVLGTSNGEHLARTVVFATGPITESKTPVLPGLESFSGEMFHSAKWNHDY
CCCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHCCCHHCCCCCCCCC
DLTGKRVAVIGTGASAIQFVPQIQPKVKELFVFQRTAPWVLPKPDLPLGDRVKQTIEVLP
CCCCCEEEEEECCHHHHHHHHCCCHHHHHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
VIQRGWRNAVSRSLNVINFGLRNPKVLRPISTAAKQLLRLQISDKALRKAVTPDFTLGCK
HHHHHHHHHHHHCCEEEEECCCCCCEECHHHHHHHHHHHHHHCHHHHHHHCCCCHHHCCE
RVLFANDYYPALQADNTHLIPHGLVEVDGNTVVAANGERHEVDVIIWGTGFEVSHPPIGS
EEEEECCCCCCEECCCCEECCCCEEEECCCEEEEECCCCEEEEEEEEECCCCCCCCCCCC
KVVNANGDRLSDLWKDTSPEAYLGAALENTPNAFLVLGPNVLVYDSFIGLAEAQLDYIID
EEECCCCCHHHHHHCCCCCCCEEEHHHCCCCCEEEEECCCEEEEECHHHHHHHHHHHHHH
GLKKVKDNDIGKISIRSDVLRQHNAKVQKHLKGTVFNSGGCKSYYLDQNGRNFAAWPWSL
HHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCEEECCCCCEEEEECCCCCEEEECCCHH
AELKRRLSVFDLDDYDVTYRNEAVLSKVS
HHHHHHCCEEECCCCCEEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]