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The map label for this gene is nudH [H]

Identifier: 110835210

GI number: 110835210

Start: 2673790

End: 2674332

Strand: Reverse

Name: nudH [H]

Synonym: ABO_2349

Alternate gene names: 110835210

Gene position: 2674332-2673790 (Counterclockwise)

Preceding gene: 110835213

Following gene: 110835209

Centisome position: 85.71

GC content: 53.78

Gene sequence:

>543_bases
ATGACAGGCATTATTGATGACAAAGGATTTCGGCTGAATGTCGGAATTATTATTGCTGGCCAAGATGGTCGGGTGTTCTG
GGGTCGCCGGGTTGGCAACCGCGATGCCTGGCAATTTCCGCAAGGCGGCATGATGCCGGGGGAAACCCCGGAAGAAACAC
TGTTTCGTGAACTGGAAGAAGAGGTGGGTCTGCTTCCTGAGCATGTGCATATCGTCGCCAGTACCGAAGGTTGGCTGACC
TACCGGTTGCCACGTCGCTTTTTGCGCCGGCCTCGTAACCGCCCCCATTGCATCGGTCAACGCCAGAAATGGTTTTTACT
GCAGCTGACAGCGGGAGAAGAAGCGATTGACCTGTTTACCAGTAATAGTCCGGAGTTTAAGGACTGGCGCTGGGTAAACT
ACTGGTACCCGATACAGAAGGTGGTGCATTTCAAACGTGGGGTCTATGCCCGAGCGTTGCGGGAATTAGCGCCGGCTCTG
AAGAAAGGAAAGCGTACTCCTCATACTAATCAGACTGTGCCTGGAGACTCACCCGATGCTTGA

Upstream 100 bases:

>100_bases
TTTGTTGCAGGGTTGTGCATTGATCGCAGGTTGCCCGGCAAGGTTTAATGGGCTGATAAGGAGCCAGAGTCCACGATTGC
GCGAGGCTCGAAGGGACAAG

Downstream 100 bases:

>100_bases
TACTCTTCGACGTATTGTTCAGGAAGTGAACAACGCGGCGGATATCCCCAGCGCGCTGGACTTGATGGCCAAGCGGGTAC
GCGATGCCATGGGTACAGAA

Product: (di)nucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MTGIIDDKGFRLNVGIIIAGQDGRVFWGRRVGNRDAWQFPQGGMMPGETPEETLFRELEEEVGLLPEHVHIVASTEGWLT
YRLPRRFLRRPRNRPHCIGQRQKWFLLQLTAGEEAIDLFTSNSPEFKDWRWVNYWYPIQKVVHFKRGVYARALRELAPAL
KKGKRTPHTNQTVPGDSPDA

Sequences:

>Translated_180_residues
MTGIIDDKGFRLNVGIIIAGQDGRVFWGRRVGNRDAWQFPQGGMMPGETPEETLFRELEEEVGLLPEHVHIVASTEGWLT
YRLPRRFLRRPRNRPHCIGQRQKWFLLQLTAGEEAIDLFTSNSPEFKDWRWVNYWYPIQKVVHFKRGVYARALRELAPAL
KKGKRTPHTNQTVPGDSPDA
>Mature_179_residues
TGIIDDKGFRLNVGIIIAGQDGRVFWGRRVGNRDAWQFPQGGMMPGETPEETLFRELEEEVGLLPEHVHIVASTEGWLTY
RLPRRFLRRPRNRPHCIGQRQKWFLLQLTAGEEAIDLFTSNSPEFKDWRWVNYWYPIQKVVHFKRGVYARALRELAPALK
KGKRTPHTNQTVPGDSPDA

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=157, Percent_Identity=54.140127388535, Blast_Score=184, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 20892; Mature: 20761

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGIIDDKGFRLNVGIIIAGQDGRVFWGRRVGNRDAWQFPQGGMMPGETPEETLFRELEE
CCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
EVGLLPEHVHIVASTEGWLTYRLPRRFLRRPRNRPHCIGQRQKWFLLQLTAGEEAIDLFT
HHCCCCCCEEEEEECCCEEEEHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCEEEEEC
SNSPEFKDWRWVNYWYPIQKVVHFKRGVYARALRELAPALKKGKRTPHTNQTVPGDSPDA
CCCCCCCCEEEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGIIDDKGFRLNVGIIIAGQDGRVFWGRRVGNRDAWQFPQGGMMPGETPEETLFRELEE
CCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
EVGLLPEHVHIVASTEGWLTYRLPRRFLRRPRNRPHCIGQRQKWFLLQLTAGEEAIDLFT
HHCCCCCCEEEEEECCCEEEEHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCEEEEEC
SNSPEFKDWRWVNYWYPIQKVVHFKRGVYARALRELAPALKKGKRTPHTNQTVPGDSPDA
CCCCCCCCEEEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA