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The map label for this gene is ascD [H]

Identifier: 110835176

GI number: 110835176

Start: 2641583

End: 2642809

Strand: Direct

Name: ascD [H]

Synonym: ABO_2315

Alternate gene names: 110835176

Gene position: 2641583-2642809 (Clockwise)

Preceding gene: 110835175

Following gene: 110835177

Centisome position: 84.66

GC content: 59.58

Gene sequence:

>1227_bases
ATGGCATCGCGCTGGCCTTTGTCGTCAGCCGCATCCTGTTCACGCTTTGCTACGTGGCAGACTGGGCCAGTGCGCGCACC
TTGGTTTGGGCCTTCGGCATGGGTTGTATCGTTGCGCTGTTTGTTGGCGTTGGCGGCTAAGAGAAAAGCAATGGATAACG
AACGCTGCCTCCAGCCTGCGCTGGGGGTAGCGTCAAGACTATCGAACTCTCCAATATCCATTCCCTCACCCATGACCCAG
ACCTTCACCATTACCGTCAACGGCAAGGGCGCCTTCCCCTGCCGCGCAGACCAGAGCATTGTCGAGGCCGGGCAGCAGGC
GGGCTTCGGCTTTCCCGTCGCCTGCCGTAATGGCGTGTGCGAGCGCTGCATGGGCCAACTCCGCCATGGGCAAGTGCAGC
AAAAAAAACGCACTATTCACGCAGGCGAAGACGACCCCTCCGGGGTGCTATACTGCGTTGCCCAGCCACTCAGCGATTGT
GAGATTGATGTGCCCGAGGTAACTGCGCCCGGCGAATTGCCGGTCCACCAGATCCATTGCCAAATTCAGCAAATCGACGC
CCTCAACCACGACGTGAGTCGTGTCTGGCTGCGCCTGCCAGCAGGCAAGAAAATCCAGTGGCATGCGGGCCAGTACCTAA
TGCTGAATCTGCACGGTGAGAGCTACCCCTTTTCTATTGCTAACCATTGCCATGGGCGCAATATCGAACTGCACATTCGC
CACGGGGATGACAACAGCGCCACCCAAGACATCATGGCCAGCCTGCAATCCGAGCACACCGTCAGCACCACCCTGCCCGC
CGGCCTGCGCTTTATCGACAGCGCCCCGGAACATCCGGTGTGGTTTATTTGCGGCTCCACCGGCTTTGCGCCAGTGAAAG
CCATGATCGAGCGTCTGATCGCGCTGAATTTCTCTTTGCCGGTACGGCTGTTCTGGGGTGCCCGCACCGATGCAGACCTG
TATCTGCCGCATTTGCCCGCCCAATGGCAGGAAGCCCTAGCCGATTTTGACTTCGTTACCTCCTTGTCCGACATACGCCA
CCCGGACCATGCCGAAGGGCTGGTGCACGAAGCCGCATTGGAAGCGCTCGGAGAACCCGACCTGCCGTTATTCTTTCTGG
GTGGCTCGCCACCCATGGGCTGGGCCGTGTTCGACGCACTGGTCGCCGAAGGCGTTCCCGCCGGGAATATTCATTGCGAC
GTTTTTGATTACGCGCCACGAGACTAG

Upstream 100 bases:

>100_bases
GCGCACTGGGCCCAACAAAACGGCTTTGAAGTCACCCCGGCTTTTGCCGCTGCGGTAATCATTGCCCACCTGGCGGCCAC
ATCACCGCAGGGCACCATTG

Downstream 100 bases:

>100_bases
CAGCAGAGCTCAAGCTACAAACGGCATCACGCATTAGGCCCACGCTTCCCGGGCTGGCAACAACCGGGCTCGCGTTGTAG
CTTGTACCTTGCGGTTTGTT

Product: iron-sulfur-binding oxidoreductase

Products: NAD(P); FMNH2; 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: CDP-6-deoxy-delta-3,4-glucoseen reductase; E3 [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MASRWPLSSAASCSRFATWQTGPVRAPWFGPSAWVVSLRCLLALAAKRKAMDNERCLQPALGVASRLSNSPISIPSPMTQ
TFTITVNGKGAFPCRADQSIVEAGQQAGFGFPVACRNGVCERCMGQLRHGQVQQKKRTIHAGEDDPSGVLYCVAQPLSDC
EIDVPEVTAPGELPVHQIHCQIQQIDALNHDVSRVWLRLPAGKKIQWHAGQYLMLNLHGESYPFSIANHCHGRNIELHIR
HGDDNSATQDIMASLQSEHTVSTTLPAGLRFIDSAPEHPVWFICGSTGFAPVKAMIERLIALNFSLPVRLFWGARTDADL
YLPHLPAQWQEALADFDFVTSLSDIRHPDHAEGLVHEAALEALGEPDLPLFFLGGSPPMGWAVFDALVAEGVPAGNIHCD
VFDYAPRD

Sequences:

>Translated_408_residues
MASRWPLSSAASCSRFATWQTGPVRAPWFGPSAWVVSLRCLLALAAKRKAMDNERCLQPALGVASRLSNSPISIPSPMTQ
TFTITVNGKGAFPCRADQSIVEAGQQAGFGFPVACRNGVCERCMGQLRHGQVQQKKRTIHAGEDDPSGVLYCVAQPLSDC
EIDVPEVTAPGELPVHQIHCQIQQIDALNHDVSRVWLRLPAGKKIQWHAGQYLMLNLHGESYPFSIANHCHGRNIELHIR
HGDDNSATQDIMASLQSEHTVSTTLPAGLRFIDSAPEHPVWFICGSTGFAPVKAMIERLIALNFSLPVRLFWGARTDADL
YLPHLPAQWQEALADFDFVTSLSDIRHPDHAEGLVHEAALEALGEPDLPLFFLGGSPPMGWAVFDALVAEGVPAGNIHCD
VFDYAPRD
>Mature_407_residues
ASRWPLSSAASCSRFATWQTGPVRAPWFGPSAWVVSLRCLLALAAKRKAMDNERCLQPALGVASRLSNSPISIPSPMTQT
FTITVNGKGAFPCRADQSIVEAGQQAGFGFPVACRNGVCERCMGQLRHGQVQQKKRTIHAGEDDPSGVLYCVAQPLSDCE
IDVPEVTAPGELPVHQIHCQIQQIDALNHDVSRVWLRLPAGKKIQWHAGQYLMLNLHGESYPFSIANHCHGRNIELHIRH
GDDNSATQDIMASLQSEHTVSTTLPAGLRFIDSAPEHPVWFICGSTGFAPVKAMIERLIALNFSLPVRLFWGARTDADLY
LPHLPAQWQEALADFDFVTSLSDIRHPDHAEGLVHEAALEALGEPDLPLFFLGGSPPMGWAVFDALVAEGVPAGNIHCDV
FDYAPRD

Specific function: Participates in the conversion of CDP-6-deoxy-D-glycero- L-threo-4-hexulose to 3,6-dideoxy-D-glycero-D-glycero-4-hexulose together with CDP-6-deoxy-D-glycero-L-threo-4-hexulose-3-dehydrase (E1) in two consecutive steps. The detailed mechanism of E3 is not

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI2367314, Length=146, Percent_Identity=27.3972602739726, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.5.1.29 [C]

Molecular weight: Translated: 44599; Mature: 44468

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRWPLSSAASCSRFATWQTGPVRAPWFGPSAWVVSLRCLLALAAKRKAMDNERCLQPA
CCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LGVASRLSNSPISIPSPMTQTFTITVNGKGAFPCRADQSIVEAGQQAGFGFPVACRNGVC
HHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCHHHHCCHH
ERCMGQLRHGQVQQKKRTIHAGEDDPSGVLYCVAQPLSDCEIDVPEVTAPGELPVHQIHC
HHHHHHHHCCHHHHHHHHEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
QIQQIDALNHDVSRVWLRLPAGKKIQWHAGQYLMLNLHGESYPFSIANHCHGRNIELHIR
HHHHHHHHCCCHHEEEEECCCCCEEEEECCCEEEEEECCCCCCCHHHHCCCCCCEEEEEE
HGDDNSATQDIMASLQSEHTVSTTLPAGLRFIDSAPEHPVWFICGSTGFAPVKAMIERLI
ECCCCHHHHHHHHHHHCCCEEEECCCHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHH
ALNFSLPVRLFWGARTDADLYLPHLPAQWQEALADFDFVTSLSDIRHPDHAEGLVHEAAL
HCCCCCCEEEEECCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EALGEPDLPLFFLGGSPPMGWAVFDALVAEGVPAGNIHCDVFDYAPRD
HHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
ASRWPLSSAASCSRFATWQTGPVRAPWFGPSAWVVSLRCLLALAAKRKAMDNERCLQPA
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LGVASRLSNSPISIPSPMTQTFTITVNGKGAFPCRADQSIVEAGQQAGFGFPVACRNGVC
HHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCHHHHCCHH
ERCMGQLRHGQVQQKKRTIHAGEDDPSGVLYCVAQPLSDCEIDVPEVTAPGELPVHQIHC
HHHHHHHHCCHHHHHHHHEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
QIQQIDALNHDVSRVWLRLPAGKKIQWHAGQYLMLNLHGESYPFSIANHCHGRNIELHIR
HHHHHHHHCCCHHEEEEECCCCCEEEEECCCEEEEEECCCCCCCHHHHCCCCCCEEEEEE
HGDDNSATQDIMASLQSEHTVSTTLPAGLRFIDSAPEHPVWFICGSTGFAPVKAMIERLI
ECCCCHHHHHHHHHHHCCCEEEECCCHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHH
ALNFSLPVRLFWGARTDADLYLPHLPAQWQEALADFDFVTSLSDIRHPDHAEGLVHEAAL
HCCCCCCEEEEECCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EALGEPDLPLFFLGGSPPMGWAVFDALVAEGVPAGNIHCDVFDYAPRD
HHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD(P)H2; FMN [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NAD(P)H2; FMN; 2 2-octaprenylphenol; O2 [C]

Specific reaction: NAD(P)H2 + FMN = NAD(P) + FMNH2 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10931327; 11586360; 12142430 [H]