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The map label for this gene is cysI-1 [H]

Identifier: 110834986

GI number: 110834986

Start: 2429834

End: 2430256

Strand: Direct

Name: cysI-1 [H]

Synonym: ABO_2125

Alternate gene names: 110834986

Gene position: 2429834-2430256 (Clockwise)

Preceding gene: 110834985

Following gene: 110834987

Centisome position: 77.88

GC content: 55.79

Gene sequence:

>423_bases
ATGACCACCAACCAGAACCTGCAGCTGACCCACGTGGAAGAACACGAACGGGAACAGATCAGCTGGCGACTGGACGATTT
AGGTCTGAGCCAGCGGCTCAAGCCCGACCTGCAAGCCGCCCATATGCTCAGTTGCGTAGCCTTCCCCACCTGCGGTTTGG
CCATGGCCGAAGCGGAACGCTACATGTCAGACCCGCTTGATCTGTTTAATCGCCTCAAACAGCAGTACGGCCTCAGACAA
GTACCGATCACCTTGCGCGTAACCGGTTACCCAAACGGGTGTGCTCGCCCTTATCTCGCAGAAATTGCCCTAACTGCCGC
GCTCCGGGACTCTACAACTTATACCTGGGCAGCAGTTTTAACGGCGACAGACTCAACCGTCTGTACGCCAGCAACGTCAA
TGAAAGCCTTTTCATTGACCTGA

Upstream 100 bases:

>100_bases
TGATTGCCGAGGGCAGCGGCATCTTGAAAATGGCCGTGTCGATGGCGCCCTGCGAGATCAACTGGGAGGGTTTTTCCAGC
AGTTCGGCGGACGTATCCGC

Downstream 100 bases:

>100_bases
TTGCTCCGTTGTTCGAAGCCTTTGCCCAGCAAAGAGAGTGTGGCGAATCGTTTGGTGACTTCCTCATTCGCAGTCAGCAA
CTCGATTGCGAACGTGATAA

Product: sulfite reductase

Products: NA

Alternate protein names: SiR-HP; SiRHP [H]

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MTTNQNLQLTHVEEHEREQISWRLDDLGLSQRLKPDLQAAHMLSCVAFPTCGLAMAEAERYMSDPLDLFNRLKQQYGLRQ
VPITLRVTGYPNGCARPYLAEIALTAALRDSTTYTWAAVLTATDSTVCTPATSMKAFSLT

Sequences:

>Translated_140_residues
MTTNQNLQLTHVEEHEREQISWRLDDLGLSQRLKPDLQAAHMLSCVAFPTCGLAMAEAERYMSDPLDLFNRLKQQYGLRQ
VPITLRVTGYPNGCARPYLAEIALTAALRDSTTYTWAAVLTATDSTVCTPATSMKAFSLT
>Mature_139_residues
TTNQNLQLTHVEEHEREQISWRLDDLGLSQRLKPDLQAAHMLSCVAFPTCGLAMAEAERYMSDPLDLFNRLKQQYGLRQV
PITLRVTGYPNGCARPYLAEIALTAALRDSTTYTWAAVLTATDSTVCTPATSMKAFSLT

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate [H]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

Organism=Escherichia coli, GI1789122, Length=106, Percent_Identity=41.5094339622642, Blast_Score=87, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6322597, Length=112, Percent_Identity=37.5, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011786
- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 15610; Mature: 15479

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNQNLQLTHVEEHEREQISWRLDDLGLSQRLKPDLQAAHMLSCVAFPTCGLAMAEAER
CCCCCCEEEEECCHHHHHHHEEECCCCCCHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHH
YMSDPLDLFNRLKQQYGLRQVPITLRVTGYPNGCARPYLAEIALTAALRDSTTYTWAAVL
HHCCHHHHHHHHHHHCCCEECCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEE
TATDSTVCTPATSMKAFSLT
EECCCCEECCCCCCEEEECC
>Mature Secondary Structure 
TTNQNLQLTHVEEHEREQISWRLDDLGLSQRLKPDLQAAHMLSCVAFPTCGLAMAEAER
CCCCCEEEEECCHHHHHHHEEECCCCCCHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHH
YMSDPLDLFNRLKQQYGLRQVPITLRVTGYPNGCARPYLAEIALTAALRDSTTYTWAAVL
HHCCHHHHHHHHHHHCCCEECCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEE
TATDSTVCTPATSMKAFSLT
EECCCCEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA