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The map label for this gene is 110636352

Identifier: 110636352

GI number: 110636352

Start: 4331445

End: 4333001

Strand: Reverse

Name: 110636352

Synonym: Meso_4028

Alternate gene names: NA

Gene position: 4333001-4331445 (Counterclockwise)

Preceding gene: 110636353

Following gene: 110636350

Centisome position: 98.2

GC content: 61.79

Gene sequence:

>1557_bases
ATGAGGAGCGAGGTCTTTCAGGAAGACGCGCCGGCTTTCGGCGCGCGCGGTACGGTGCTGGCGCCGGGCCGCAACTGCCA
GCAGATCGCGATGGCTCATCGGGCCGCCTTTCTCATCGACGCGGAGGCCTATTTCGCGGCGTTGGATGAGGCGCTCAGGA
GCGCTACCCGCTCCATATTCATCATCGGCTGGGACTTCGATGCCCGGATTCAGCTCCGGCCGCAGGATGGAGAGGATGCC
CCCAACCTGGGTACTTTGCTGCGGAAGCTTGTTGAGGAACGGCCGGAACTCGAAATCCGCATTCTGGTATGGAGTCTTGC
TGCGCTGCATGCGCCGGGAGCAACCATTCCGCTCGTTTTCGGCGCGGAGTGGGAGGAGCACCCGCGCATTCGCCTCCGGC
TCGACACGCACCATCCCATCCATGCGGCGCACCACCAGAAGATCGTCACCATTGACGATTCGCTGGCCTTCATCGGCGGC
ATGGACCTGACGGTCGGCCGCTGGGACACCCCGAAACACAGGAAAGACGATCCACGCAGGAATGGGCCTAACGGTATCGC
GTGCAACCCCGTTCATGATCTGCAAATGGCGCTGGACGGGCCTGTCGCCCGCGCCATTGCGGAGGTGGCGCGTGACCGAT
GGGTCGAGTTGACCGGGGAAAAGGTTCCGTTCTCGAAGCCTGCCGAGAGGTGGCCGGAAAATCTTGCCACTGATTTCAGC
CACGTTCCCGTGGCGATTGCCCGGACCATTCCCGGGCTTGGCGGGGCAAAAGGAGTGGGAGAAGTAGCGCTTCTCACGGG
CGATCTGCTCAAATCCGCCAGGCGCACTGTCTATATCGAAGCACAATATTTCACCGCCAAACGCCTGCGGAAAATCTTGC
GCAAGGTGCTTTCGCGCCGGCACGGACCTGAAATCGTCGTCATCTGCACGCGCCACGCCAACGGGTTCATCGAGCGTTTC
ATCATGGGCGCCAATCGCGAGCGTCTTCTTCGCAGCTTGAAGCGCTGGGACCGCTATGACCGGCTGCGTGTCTACTATCC
CGCCCTAGACGGGCAGGAGGACGACGGAATCCTCCTCGTCCACGCTAAGCTGATGATCATCGACGACCGGTTCCTTCGGC
TAGGCTCGGCCAATCTGAACAACCGATCGATGGGACTGGATACCGAATGCGACGTTGTCATCGAAGCGGACAGGCCCGAG
ACTCGCCAGGCGATCGCACGCTGCCGCGAACGCCTGATCGCGGAGCATCTCGACCTGGATCCCGCCATGGTTCGCGAAAC
CATGCGGCAGGAAAATTCGGTGATCCGCACGATCGAAAAGCTCAACCGCCAAAGCGGGCGCTGTCTTTGCGCAATCGATG
TTCGTCCAGGACCGACGCATTCGTTTCCCGGAACGCGCCTGCTCGATCCGGAAAGGCCGTTCCGTCTGGTTGAATGGCTG
CGTTCCAAGTGGCGGCGCATCTTCGGTCAAGACGCCGTTTCCGCGCCCGGCCGGGACAGCAACGCTTCCGACAGGGCGAG
CAGGATGCTGCCCATGAAAAGCGGCAGAAGGAAATAG

Upstream 100 bases:

>100_bases
GACAGGCGGCTGATCCGAGAACAGGTTCACAACTGCTCCGCGAACCTATTTGCAGGTTGCGCGTTGAAGCCTCGTGACTC
ACGTGGGCAAAGGGACCTGG

Downstream 100 bases:

>100_bases
GCGAAACGGAAGACGAGCACGGCGCCGATAAGATGGGCTTGCGGCAGCAGATAGAGCACGACGCTTTCGATCACGCCGAG
CCCGCCCGGAGCGTGGGTGA

Product: phospholipase D/transphosphatidylase

Products: NA

Alternate protein names: Phospholipase D; SNARE Associated Golgi Protein; Phospholipase D Family Protein; SNARE Associated Golgi Protein-Like Protein; SNARE Associated Golgi Protein-Related Protein; Phospholipase D Domain Protein; Transmembrane Phospholipase Protein; SNARE Associated Golgi Protein-Associated Protein; Phospholipase/Transphosphatidylase; Phospholipase D Alpha; Phospholipase Protein; Phospholipase D Active Site Motif Domain Protein; Phospholipase; Phospholipase D Protein; Phospholipase/Phosphatidylserine Synthase; Phospholipase D Superfamily Protein

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MRSEVFQEDAPAFGARGTVLAPGRNCQQIAMAHRAAFLIDAEAYFAALDEALRSATRSIFIIGWDFDARIQLRPQDGEDA
PNLGTLLRKLVEERPELEIRILVWSLAALHAPGATIPLVFGAEWEEHPRIRLRLDTHHPIHAAHHQKIVTIDDSLAFIGG
MDLTVGRWDTPKHRKDDPRRNGPNGIACNPVHDLQMALDGPVARAIAEVARDRWVELTGEKVPFSKPAERWPENLATDFS
HVPVAIARTIPGLGGAKGVGEVALLTGDLLKSARRTVYIEAQYFTAKRLRKILRKVLSRRHGPEIVVICTRHANGFIERF
IMGANRERLLRSLKRWDRYDRLRVYYPALDGQEDDGILLVHAKLMIIDDRFLRLGSANLNNRSMGLDTECDVVIEADRPE
TRQAIARCRERLIAEHLDLDPAMVRETMRQENSVIRTIEKLNRQSGRCLCAIDVRPGPTHSFPGTRLLDPERPFRLVEWL
RSKWRRIFGQDAVSAPGRDSNASDRASRMLPMKSGRRK

Sequences:

>Translated_518_residues
MRSEVFQEDAPAFGARGTVLAPGRNCQQIAMAHRAAFLIDAEAYFAALDEALRSATRSIFIIGWDFDARIQLRPQDGEDA
PNLGTLLRKLVEERPELEIRILVWSLAALHAPGATIPLVFGAEWEEHPRIRLRLDTHHPIHAAHHQKIVTIDDSLAFIGG
MDLTVGRWDTPKHRKDDPRRNGPNGIACNPVHDLQMALDGPVARAIAEVARDRWVELTGEKVPFSKPAERWPENLATDFS
HVPVAIARTIPGLGGAKGVGEVALLTGDLLKSARRTVYIEAQYFTAKRLRKILRKVLSRRHGPEIVVICTRHANGFIERF
IMGANRERLLRSLKRWDRYDRLRVYYPALDGQEDDGILLVHAKLMIIDDRFLRLGSANLNNRSMGLDTECDVVIEADRPE
TRQAIARCRERLIAEHLDLDPAMVRETMRQENSVIRTIEKLNRQSGRCLCAIDVRPGPTHSFPGTRLLDPERPFRLVEWL
RSKWRRIFGQDAVSAPGRDSNASDRASRMLPMKSGRRK
>Mature_518_residues
MRSEVFQEDAPAFGARGTVLAPGRNCQQIAMAHRAAFLIDAEAYFAALDEALRSATRSIFIIGWDFDARIQLRPQDGEDA
PNLGTLLRKLVEERPELEIRILVWSLAALHAPGATIPLVFGAEWEEHPRIRLRLDTHHPIHAAHHQKIVTIDDSLAFIGG
MDLTVGRWDTPKHRKDDPRRNGPNGIACNPVHDLQMALDGPVARAIAEVARDRWVELTGEKVPFSKPAERWPENLATDFS
HVPVAIARTIPGLGGAKGVGEVALLTGDLLKSARRTVYIEAQYFTAKRLRKILRKVLSRRHGPEIVVICTRHANGFIERF
IMGANRERLLRSLKRWDRYDRLRVYYPALDGQEDDGILLVHAKLMIIDDRFLRLGSANLNNRSMGLDTECDVVIEADRPE
TRQAIARCRERLIAEHLDLDPAMVRETMRQENSVIRTIEKLNRQSGRCLCAIDVRPGPTHSFPGTRLLDPERPFRLVEWL
RSKWRRIFGQDAVSAPGRDSNASDRASRMLPMKSGRRK

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI194272176, Length=151, Percent_Identity=31.7880794701987, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI4505873, Length=151, Percent_Identity=31.7880794701987, Blast_Score=67, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322883, Length=230, Percent_Identity=27.8260869565217, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 58627; Mature: 58627

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSEVFQEDAPAFGARGTVLAPGRNCQQIAMAHRAAFLIDAEAYFAALDEALRSATRSIF
CCCCHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHCCEEE
IIGWDFDARIQLRPQDGEDAPNLGTLLRKLVEERPELEIRILVWSLAALHAPGATIPLVF
EEEECCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEHHHHHCCCCCCEEEEE
GAEWEEHPRIRLRLDTHHPIHAAHHQKIVTIDDSLAFIGGMDLTVGRWDTPKHRKDDPRR
CCCCCCCCCEEEEECCCCCCCHHCCCEEEEECCCCHHHCCCEEEECCCCCCCCCCCCCCC
NGPNGIACNPVHDLQMALDGPVARAIAEVARDRWVELTGEKVPFSKPAERWPENLATDFS
CCCCCEEECCHHHHHHHHCCHHHHHHHHHHHHCEEEECCCCCCCCCCHHHCCHHHHCCCC
HVPVAIARTIPGLGGAKGVGEVALLTGDLLKSARRTVYIEAQYFTAKRLRKILRKVLSRR
CCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHC
HGPEIVVICTRHANGFIERFIMGANRERLLRSLKRWDRYDRLRVYYPALDGQEDDGILLV
CCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEE
HAKLMIIDDRFLRLGSANLNNRSMGLDTECDVVIEADRPETRQAIARCRERLIAEHLDLD
EEEEEEEEHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCC
PAMVRETMRQENSVIRTIEKLNRQSGRCLCAIDVRPGPTHSFPGTRLLDPERPFRLVEWL
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHH
RSKWRRIFGQDAVSAPGRDSNASDRASRMLPMKSGRRK
HHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRSEVFQEDAPAFGARGTVLAPGRNCQQIAMAHRAAFLIDAEAYFAALDEALRSATRSIF
CCCCHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHCCEEE
IIGWDFDARIQLRPQDGEDAPNLGTLLRKLVEERPELEIRILVWSLAALHAPGATIPLVF
EEEECCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEHHHHHCCCCCCEEEEE
GAEWEEHPRIRLRLDTHHPIHAAHHQKIVTIDDSLAFIGGMDLTVGRWDTPKHRKDDPRR
CCCCCCCCCEEEEECCCCCCCHHCCCEEEEECCCCHHHCCCEEEECCCCCCCCCCCCCCC
NGPNGIACNPVHDLQMALDGPVARAIAEVARDRWVELTGEKVPFSKPAERWPENLATDFS
CCCCCEEECCHHHHHHHHCCHHHHHHHHHHHHCEEEECCCCCCCCCCHHHCCHHHHCCCC
HVPVAIARTIPGLGGAKGVGEVALLTGDLLKSARRTVYIEAQYFTAKRLRKILRKVLSRR
CCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHC
HGPEIVVICTRHANGFIERFIMGANRERLLRSLKRWDRYDRLRVYYPALDGQEDDGILLV
CCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEE
HAKLMIIDDRFLRLGSANLNNRSMGLDTECDVVIEADRPETRQAIARCRERLIAEHLDLD
EEEEEEEEHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCC
PAMVRETMRQENSVIRTIEKLNRQSGRCLCAIDVRPGPTHSFPGTRLLDPERPFRLVEWL
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHH
RSKWRRIFGQDAVSAPGRDSNASDRASRMLPMKSGRRK
HHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA