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The map label for this gene is yggV [C]

Identifier: 110636338

GI number: 110636338

Start: 4319867

End: 4320514

Strand: Reverse

Name: yggV [C]

Synonym: Meso_4014

Alternate gene names: 110636338

Gene position: 4320514-4319867 (Counterclockwise)

Preceding gene: 110636339

Following gene: 110636337

Centisome position: 97.92

GC content: 63.58

Gene sequence:

>648_bases
GTGAGGCCAATAGACAACAAGAAGTTCGTGCTTGCCAGCCACAACAAGGGCAAACTCGATGAGTTCGCCGGTCTGCTGGC
GCCGTTTGGCTACGAGATACGCTCGGCAGCCGAGTTGGGCCTGCCGGAGCCGGAAGAGACCGGCACCGAATTCGAGCAGA
ACGCCTATATAAAGGCTTCGGCTGCCGCAAAGGCGACTGGGCTGCCGGCCTTATCGGACGATTCCGGGATGTGCGTGGAT
GCGCTGGGCGGCGCGCCGGGCGTCTACACAGCCGACTGGGCGACATTGCCTGATGGGCGCCGCGATTTCGGGATAGCCAT
GGAAAAAGTGGAAAAGCTGCTGCGCGAGAAAGGGGCTACGTCCCCCGAGCAGCGGCGCGCGCGATTTGTGGCTGTCCTGT
GCCTGTGTTTTCCCGACGGCGAAGCTGAATTCTACCGCGGCGAGGTGGAAGGCCATCTCGTCTGGCCGCCGCGCGGCGGG
CTTGGGTTCGGTTACGACCCGGTGTTCCAGCCCGATGGCCACCAAAGAACCTTCGGCGAGATGACGGCGGCGGAAAAGCA
CGGCTGGAAACCGGGGGATGCGCAGGCTCTTTCGCATCGTGCCCGCGCGTTTCAGAAATTCGCACGGGCGAGGCTGGGCG
TCGCATGA

Upstream 100 bases:

>100_bases
AAGCTGATTTCGTGTGGCCGAAGGGTGGCAGATCCATCTATTTTCGTGACCCCTCCGGCAATTCTCTGGAATTCGCGGAG
CCGCGCATCTGGGGTTTTTC

Downstream 100 bases:

>100_bases
ACAAGCCGCTCGACGAGGGGCCTGGCTTCGGCGTTTACGTTCACTGGCCCTTCTGCGCGGCCAAATGCCCTTATTGCGAC
TTCAACAGCCATGTACGCCA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MRPIDNKKFVLASHNKGKLDEFAGLLAPFGYEIRSAAELGLPEPEETGTEFEQNAYIKASAAAKATGLPALSDDSGMCVD
ALGGAPGVYTADWATLPDGRRDFGIAMEKVEKLLREKGATSPEQRRARFVAVLCLCFPDGEAEFYRGEVEGHLVWPPRGG
LGFGYDPVFQPDGHQRTFGEMTAAEKHGWKPGDAQALSHRARAFQKFARARLGVA

Sequences:

>Translated_215_residues
MRPIDNKKFVLASHNKGKLDEFAGLLAPFGYEIRSAAELGLPEPEETGTEFEQNAYIKASAAAKATGLPALSDDSGMCVD
ALGGAPGVYTADWATLPDGRRDFGIAMEKVEKLLREKGATSPEQRRARFVAVLCLCFPDGEAEFYRGEVEGHLVWPPRGG
LGFGYDPVFQPDGHQRTFGEMTAAEKHGWKPGDAQALSHRARAFQKFARARLGVA
>Mature_215_residues
MRPIDNKKFVLASHNKGKLDEFAGLLAPFGYEIRSAAELGLPEPEETGTEFEQNAYIKASAAAKATGLPALSDDSGMCVD
ALGGAPGVYTADWATLPDGRRDFGIAMEKVEKLLREKGATSPEQRRARFVAVLCLCFPDGEAEFYRGEVEGHLVWPPRGG
LGFGYDPVFQPDGHQRTFGEMTAAEKHGWKPGDAQALSHRARAFQKFARARLGVA

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=204, Percent_Identity=30.3921568627451, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI31657144, Length=175, Percent_Identity=30.8571428571429, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1789324, Length=206, Percent_Identity=38.3495145631068, Blast_Score=124, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6322529, Length=210, Percent_Identity=29.5238095238095, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920712, Length=200, Percent_Identity=28.5, Blast_Score=77, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 23341; Mature: 23341

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPIDNKKFVLASHNKGKLDEFAGLLAPFGYEIRSAAELGLPEPEETGTEFEQNAYIKAS
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCHHCCCCHHCCCEEEEC
AAAKATGLPALSDDSGMCVDALGGAPGVYTADWATLPDGRRDFGIAMEKVEKLLREKGAT
CCHHHCCCCCCCCCCCCEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
SPEQRRARFVAVLCLCFPDGEAEFYRGEVEGHLVWPPRGGLGFGYDPVFQPDGHQRTFGE
CHHHHHHHHHHHHEEECCCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHH
MTAAEKHGWKPGDAQALSHRARAFQKFARARLGVA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRPIDNKKFVLASHNKGKLDEFAGLLAPFGYEIRSAAELGLPEPEETGTEFEQNAYIKAS
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCHHCCCCHHCCCEEEEC
AAAKATGLPALSDDSGMCVDALGGAPGVYTADWATLPDGRRDFGIAMEKVEKLLREKGAT
CCHHHCCCCCCCCCCCCEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
SPEQRRARFVAVLCLCFPDGEAEFYRGEVEGHLVWPPRGGLGFGYDPVFQPDGHQRTFGE
CHHHHHHHHHHHHEEECCCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHH
MTAAEKHGWKPGDAQALSHRARAFQKFARARLGVA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]