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The map label for this gene is aroC

Identifier: 110633087

GI number: 110633087

Start: 804084

End: 805178

Strand: Direct

Name: aroC

Synonym: Meso_0730

Alternate gene names: 110633087

Gene position: 804084-805178 (Clockwise)

Preceding gene: 110633085

Following gene: 110633088

Centisome position: 18.22

GC content: 62.19

Gene sequence:

>1095_bases
ATGTCGCACAACACATTCGGGCATCTTTTTCGCGTCACCACATGGGGCGAGAGCCATGGCCCCGCCATCGGCTGCGTTGT
GGATGGCTGCCCGCCCGGCATTCATTTCACGCAGGCCGAGATACAGGCAGATCTCGATCGCCGCAGGCCCGGCCAATCCC
GCTTCGTCACTCAACGCCGCGAGCCAGACGAGGTAAAGATTCTCTCCGGCGTCATGCAGGACGGCGAAACGCTGGTGACC
ACCGGCACGCCCATCTCCATGCTGATCGAAAATGTCGACCAGCGCTCCAAGGATTACGGAGAAATCGCCGAACGGTACCG
ACCCGGTCACGCCGACTATACTTATGACGCGAAATACGGGGTCAGGGATTATCGTGGCGGCGGCCGTTCATCCGCGCGCG
AAACAGCGACCCGCGTGGCGGCAGGCGCGCTCGCTCGCAAGATCGTGCCGGGCATGGTCGTTCGCGGCGCGCTCATTTCC
ATGGGTGAGAAGGAGATCGACCGCGCCAATTGGGATTGGGATTTCCTCCACGACCCGGAAAATCCATTCTTCACGCCCGA
CCCGAAATCCGTTTCCGAATTTGCTGATTATCTGGACGGTGTGCGAAAGGCGGGCTCCTCCGTAGGCGCGGTGATCGAGA
TCGTGGCCGAAGGAGTGCCGGCGGGCCTTGGCGCGCCCCTCTATGGCAAGCTCGATCAGGATATCTGCGCCAACCTGATG
TCGATCAATGCGGTCAAGGGCGTCGAGATCGGCATCGGCTTCCAGGCTGCGCGCATCCACGGTGAGGAAAATGCCGACGA
GATGCGCTCGGGCAATGATGGATATCCGCGCTTCCTCTCCAACAATGCCGGCGGGATTCTCGGCGGTATCTCGACAGGGC
AGCCCATCATTGCGCGCTTCGCGGTAAAGCCGACGTCCTCGATCCTGACACCCCGCCGCTCGATCGACCGGAAAGGGGCG
GAGGTCGAAGTTGTGACCAAGGGCAGGCACGATCCCTGCGTGGGCATTCGCGCCGTGCCGATTGGCGAGGCGATGGTCGC
CTGCGCCATTGCCGATCATTATCTGCGCCACAGGGGGCAGACGGGGAAAGGATGA

Upstream 100 bases:

>100_bases
AAGTCGCAAATGTGTCCAAACTTGCGCAATGCGCGGTTTGACCGCATCGCTAAACCGACATAGAAGCATGGCCGGCCCCT
TATGGGGAAGGAAGCTTTTT

Downstream 100 bases:

>100_bases
GCGAACGGGGAGGAGTAACCTTGCCGGACTTTCCATTCGCTGCTCCCTATTCGCTACTTGCTCAGAACGGAAACCTATAT
GCCTTATGATCAGAAACATG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSHNTFGHLFRVTTWGESHGPAIGCVVDGCPPGIHFTQAEIQADLDRRRPGQSRFVTQRREPDEVKILSGVMQDGETLVT
TGTPISMLIENVDQRSKDYGEIAERYRPGHADYTYDAKYGVRDYRGGGRSSARETATRVAAGALARKIVPGMVVRGALIS
MGEKEIDRANWDWDFLHDPENPFFTPDPKSVSEFADYLDGVRKAGSSVGAVIEIVAEGVPAGLGAPLYGKLDQDICANLM
SINAVKGVEIGIGFQAARIHGEENADEMRSGNDGYPRFLSNNAGGILGGISTGQPIIARFAVKPTSSILTPRRSIDRKGA
EVEVVTKGRHDPCVGIRAVPIGEAMVACAIADHYLRHRGQTGKG

Sequences:

>Translated_364_residues
MSHNTFGHLFRVTTWGESHGPAIGCVVDGCPPGIHFTQAEIQADLDRRRPGQSRFVTQRREPDEVKILSGVMQDGETLVT
TGTPISMLIENVDQRSKDYGEIAERYRPGHADYTYDAKYGVRDYRGGGRSSARETATRVAAGALARKIVPGMVVRGALIS
MGEKEIDRANWDWDFLHDPENPFFTPDPKSVSEFADYLDGVRKAGSSVGAVIEIVAEGVPAGLGAPLYGKLDQDICANLM
SINAVKGVEIGIGFQAARIHGEENADEMRSGNDGYPRFLSNNAGGILGGISTGQPIIARFAVKPTSSILTPRRSIDRKGA
EVEVVTKGRHDPCVGIRAVPIGEAMVACAIADHYLRHRGQTGKG
>Mature_363_residues
SHNTFGHLFRVTTWGESHGPAIGCVVDGCPPGIHFTQAEIQADLDRRRPGQSRFVTQRREPDEVKILSGVMQDGETLVTT
GTPISMLIENVDQRSKDYGEIAERYRPGHADYTYDAKYGVRDYRGGGRSSARETATRVAAGALARKIVPGMVVRGALISM
GEKEIDRANWDWDFLHDPENPFFTPDPKSVSEFADYLDGVRKAGSSVGAVIEIVAEGVPAGLGAPLYGKLDQDICANLMS
INAVKGVEIGIGFQAARIHGEENADEMRSGNDGYPRFLSNNAGGILGGISTGQPIIARFAVKPTSSILTPRRSIDRKGAE
VEVVTKGRHDPCVGIRAVPIGEAMVACAIADHYLRHRGQTGKG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=364, Percent_Identity=59.6153846153846, Blast_Score=405, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6321290, Length=371, Percent_Identity=40.4312668463612, Blast_Score=265, Evalue=9e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_MESSB (Q11KE5)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673295.1
- ProteinModelPortal:   Q11KE5
- SMR:   Q11KE5
- STRING:   Q11KE5
- GeneID:   4180208
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_0730
- NMPDR:   fig|266779.1.peg.2868
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   Q11KE5
- ProtClustDB:   PRK05382
- BioCyc:   MSP266779:MESO_0730-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39271; Mature: 39140

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNTFGHLFRVTTWGESHGPAIGCVVDGCPPGIHFTQAEIQADLDRRRPGQSRFVTQRR
CCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCHHHHHCCC
EPDEVKILSGVMQDGETLVTTGTPISMLIENVDQRSKDYGEIAERYRPGHADYTYDAKYG
CCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEECCCCC
VRDYRGGGRSSARETATRVAAGALARKIVPGMVVRGALISMGEKEIDRANWDWDFLHDPE
CHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCC
NPFFTPDPKSVSEFADYLDGVRKAGSSVGAVIEIVAEGVPAGLGAPLYGKLDQDICANLM
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
SINAVKGVEIGIGFQAARIHGEENADEMRSGNDGYPRFLSNNAGGILGGISTGQPIIARF
HHCCCCCEEEECCEEEEEECCCCCHHHHHCCCCCCCHHHCCCCCCEEECCCCCCCEEEEE
AVKPTSSILTPRRSIDRKGAEVEVVTKGRHDPCVGIRAVPIGEAMVACAIADHYLRHRGQ
ECCCCHHHCCCHHHHCCCCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCC
TGKG
CCCC
>Mature Secondary Structure 
SHNTFGHLFRVTTWGESHGPAIGCVVDGCPPGIHFTQAEIQADLDRRRPGQSRFVTQRR
CCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCHHHHHCCC
EPDEVKILSGVMQDGETLVTTGTPISMLIENVDQRSKDYGEIAERYRPGHADYTYDAKYG
CCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEECCCCC
VRDYRGGGRSSARETATRVAAGALARKIVPGMVVRGALISMGEKEIDRANWDWDFLHDPE
CHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCC
NPFFTPDPKSVSEFADYLDGVRKAGSSVGAVIEIVAEGVPAGLGAPLYGKLDQDICANLM
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
SINAVKGVEIGIGFQAARIHGEENADEMRSGNDGYPRFLSNNAGGILGGISTGQPIIARF
HHCCCCCEEEECCEEEEEECCCCCHHHHHCCCCCCCHHHCCCCCCEEECCCCCCCEEEEE
AVKPTSSILTPRRSIDRKGAEVEVVTKGRHDPCVGIRAVPIGEAMVACAIADHYLRHRGQ
ECCCCHHHCCCHHHHCCCCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCC
TGKG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA