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The map label for this gene is engA

Identifier: 110633049

GI number: 110633049

Start: 769126

End: 770538

Strand: Direct

Name: engA

Synonym: Meso_0692

Alternate gene names: 110633049

Gene position: 769126-770538 (Clockwise)

Preceding gene: 110633048

Following gene: 110633051

Centisome position: 17.43

GC content: 62.77

Gene sequence:

>1413_bases
ATGCCTTTCAAGGTCGCCATTGTCGGCCGGCCCAATGTCGGCAAGTCGACCCTCTTCAACAGGCTGGTGGGCCGCCGGAT
CGCGCTTGTCGACGATACGCCGGGCGTGACCCGCGACCGTCGGGTGCATTCCGCCCGTCTCCTCGACCTGCGTTTCGATG
TCATAGACACTGCCGGCCTCGAAGAGGCGGCAGCGCCCACCCTGGCCGGGCGTATGCGCGCGCAGACCGAAACCGCCATC
GACGAAGCTGATCTCGTTCTATTCATGATCGATGCGCGGGCCGGGCTGATGCCCGATGACCGCGCCTTTGCCGAGGTGGT
GCGCCGCAAAGGCAAGCCCGTGGTCCTGGTCGCCAACAAGACGGATGTTCGGGGAACGGATGCTGGCGTGCTTGAGGCCT
TTGCCCTGGGTTTGGGCGACCCTGTCGCCGTTTCCGCCGAGCATGGCCAGGGCATGGTCGAGCTGCGCGACGCTATTGCT
GAATTTGCCGGTCAGGCAGAAGAAGAGGAGAGGGTCACGGAGGAGGAGACCGTGCTGATCGGTGAGGACATCGATCCCGA
TTCCGAGGAGGCCCGGTACGATCCCACCAAGCCCATTCGCATTGCGGTGGTCGGCCGCCCCAACGTGGGCAAATCGACAC
TCATCAACGCGTTGATCGGCGAGGAACGCCTGCTGACCGGACCGGAGGCCGGGATCACCCGCGACTCGATTTCCGTCGAC
TGGCATTGGCGCGGCAGGGAAATAAAGCTGTTTGATACCGCCGGGATGCGGCGCAAGGCACGCGTGCAGGAAAAGCTCGA
AAAGCTTTCCGTGGGCGAGAGCCTGCGCGCCATCCGCTTCGCCGAGGTGGTTATCATCGTTTTCGACGCGACCATGCCCT
TCGAGAAGCAAGATCTCCAGATCGCGGATCTGATCGTGCGCGAGGGCAGGGCGCCTGTGATCGCCTTCAATAAATGGGAT
TTGATCGAGAACCGGCAGGAAAAGCTTGCCGAGCTGCGTGAGAAGACGGACCGGCTGCTTCCTCAGGCGCGCGGTCTTCG
GTCGGTCCCCATCTCGGCGGAAACCGGCCGCGGTCTCGATCAGTTGCTGGAAGCAGCGGTAAGCACCCATGTGGTCTGGA
ACCGGCGTGTGCCGACCGGCCCGTTGAACCGTTGGTTGGAAGCCGCGTCGACGCAGCATCCGCCGCCGGCCGTTTCAGGC
AGGCGGTTGAAGGTGAAATATATGACGCAGGTGAAGACGAGACCGCCAGGCTTCGTGCTTTCCTGCTCCCGCCCCGAGGC
CATGCCGCAGTCCTATATCCGCTATCTCGTGAATGGCCTGCGCGAAAGCTTCGACATTTTCGGCGTGCCAATCAGAATTT
CGCTCCGCGCATCCGAAAATCCCTATGCCGGAAAAGCGCGCAAGCGGACTTAG

Upstream 100 bases:

>100_bases
ATTGCGGATGATGAGCAGGCGCCTGCCGGGGCTCGTCAACGCGCGGAGATGATGATGGATCTGATCTCCGGCACCGCCAC
CGGCGAAGCTGGATAGTATC

Downstream 100 bases:

>100_bases
CAACCCAATGCCCTTTTCGGCCTAACGCTGCAGCCTCATCTCAACCGGCGGGCCGTTCCGGATCGTCTGGTAGACGACGC
AGTAGCGCTCGGTGAGCTTT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MPFKVAIVGRPNVGKSTLFNRLVGRRIALVDDTPGVTRDRRVHSARLLDLRFDVIDTAGLEEAAAPTLAGRMRAQTETAI
DEADLVLFMIDARAGLMPDDRAFAEVVRRKGKPVVLVANKTDVRGTDAGVLEAFALGLGDPVAVSAEHGQGMVELRDAIA
EFAGQAEEEERVTEEETVLIGEDIDPDSEEARYDPTKPIRIAVVGRPNVGKSTLINALIGEERLLTGPEAGITRDSISVD
WHWRGREIKLFDTAGMRRKARVQEKLEKLSVGESLRAIRFAEVVIIVFDATMPFEKQDLQIADLIVREGRAPVIAFNKWD
LIENRQEKLAELREKTDRLLPQARGLRSVPISAETGRGLDQLLEAAVSTHVVWNRRVPTGPLNRWLEAASTQHPPPAVSG
RRLKVKYMTQVKTRPPGFVLSCSRPEAMPQSYIRYLVNGLRESFDIFGVPIRISLRASENPYAGKARKRT

Sequences:

>Translated_470_residues
MPFKVAIVGRPNVGKSTLFNRLVGRRIALVDDTPGVTRDRRVHSARLLDLRFDVIDTAGLEEAAAPTLAGRMRAQTETAI
DEADLVLFMIDARAGLMPDDRAFAEVVRRKGKPVVLVANKTDVRGTDAGVLEAFALGLGDPVAVSAEHGQGMVELRDAIA
EFAGQAEEEERVTEEETVLIGEDIDPDSEEARYDPTKPIRIAVVGRPNVGKSTLINALIGEERLLTGPEAGITRDSISVD
WHWRGREIKLFDTAGMRRKARVQEKLEKLSVGESLRAIRFAEVVIIVFDATMPFEKQDLQIADLIVREGRAPVIAFNKWD
LIENRQEKLAELREKTDRLLPQARGLRSVPISAETGRGLDQLLEAAVSTHVVWNRRVPTGPLNRWLEAASTQHPPPAVSG
RRLKVKYMTQVKTRPPGFVLSCSRPEAMPQSYIRYLVNGLRESFDIFGVPIRISLRASENPYAGKARKRT
>Mature_469_residues
PFKVAIVGRPNVGKSTLFNRLVGRRIALVDDTPGVTRDRRVHSARLLDLRFDVIDTAGLEEAAAPTLAGRMRAQTETAID
EADLVLFMIDARAGLMPDDRAFAEVVRRKGKPVVLVANKTDVRGTDAGVLEAFALGLGDPVAVSAEHGQGMVELRDAIAE
FAGQAEEEERVTEEETVLIGEDIDPDSEEARYDPTKPIRIAVVGRPNVGKSTLINALIGEERLLTGPEAGITRDSISVDW
HWRGREIKLFDTAGMRRKARVQEKLEKLSVGESLRAIRFAEVVIIVFDATMPFEKQDLQIADLIVREGRAPVIAFNKWDL
IENRQEKLAELREKTDRLLPQARGLRSVPISAETGRGLDQLLEAAVSTHVVWNRRVPTGPLNRWLEAASTQHPPPAVSGR
RLKVKYMTQVKTRPPGFVLSCSRPEAMPQSYIRYLVNGLRESFDIFGVPIRISLRASENPYAGKARKRT

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=474, Percent_Identity=42.1940928270042, Blast_Score=328, Evalue=4e-91,
Organism=Escherichia coli, GI2367268, Length=169, Percent_Identity=37.8698224852071, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788919, Length=178, Percent_Identity=38.7640449438202, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_MESSB (Q11KI3)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673257.1
- ProteinModelPortal:   Q11KI3
- SMR:   Q11KI3
- STRING:   Q11KI3
- GeneID:   4180599
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_0692
- NMPDR:   fig|266779.1.peg.2829
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   Q11KI3
- ProtClustDB:   PRK00093
- BioCyc:   MSP266779:MESO_0692-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR001806
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00449
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 52136; Mature: 52004

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFKVAIVGRPNVGKSTLFNRLVGRRIALVDDTPGVTRDRRVHSARLLDLRFDVIDTAGL
CCEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHEEEEEEEEECCCCCC
EEAAAPTLAGRMRAQTETAIDEADLVLFMIDARAGLMPDDRAFAEVVRRKGKPVVLVANK
HHHHCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECC
TDVRGTDAGVLEAFALGLGDPVAVSAEHGQGMVELRDAIAEFAGQAEEEERVTEEETVLI
CCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCEEEE
GEDIDPDSEEARYDPTKPIRIAVVGRPNVGKSTLINALIGEERLLTGPEAGITRDSISVD
ECCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEE
WHWRGREIKLFDTAGMRRKARVQEKLEKLSVGESLRAIRFAEVVIIVFDATMPFEKQDLQ
EEECCCEEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHEEEEEEEEECCCCCCCCCCH
IADLIVREGRAPVIAFNKWDLIENRQEKLAELREKTDRLLPQARGLRSVPISAETGRGLD
HHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
QLLEAAVSTHVVWNRRVPTGPLNRWLEAASTQHPPPAVSGRRLKVKYMTQVKTRPPGFVL
HHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCEEE
SCSRPEAMPQSYIRYLVNGLRESFDIFGVPIRISLRASENPYAGKARKRT
ECCCCCCCHHHHHHHHHHHHHHHHHEECCEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
PFKVAIVGRPNVGKSTLFNRLVGRRIALVDDTPGVTRDRRVHSARLLDLRFDVIDTAGL
CEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHEEEEEEEEECCCCCC
EEAAAPTLAGRMRAQTETAIDEADLVLFMIDARAGLMPDDRAFAEVVRRKGKPVVLVANK
HHHHCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECC
TDVRGTDAGVLEAFALGLGDPVAVSAEHGQGMVELRDAIAEFAGQAEEEERVTEEETVLI
CCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCEEEE
GEDIDPDSEEARYDPTKPIRIAVVGRPNVGKSTLINALIGEERLLTGPEAGITRDSISVD
ECCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEE
WHWRGREIKLFDTAGMRRKARVQEKLEKLSVGESLRAIRFAEVVIIVFDATMPFEKQDLQ
EEECCCEEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHEEEEEEEEECCCCCCCCCCH
IADLIVREGRAPVIAFNKWDLIENRQEKLAELREKTDRLLPQARGLRSVPISAETGRGLD
HHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
QLLEAAVSTHVVWNRRVPTGPLNRWLEAASTQHPPPAVSGRRLKVKYMTQVKTRPPGFVL
HHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCEEE
SCSRPEAMPQSYIRYLVNGLRESFDIFGVPIRISLRASENPYAGKARKRT
ECCCCCCCHHHHHHHHHHHHHHHHHEECCEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA