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The map label for this gene is soxB [H]

Identifier: 110632948

GI number: 110632948

Start: 661257

End: 662510

Strand: Direct

Name: soxB [H]

Synonym: Meso_0591

Alternate gene names: 110632948

Gene position: 661257-662510 (Clockwise)

Preceding gene: 110632945

Following gene: 110632949

Centisome position: 14.99

GC content: 61.48

Gene sequence:

>1254_bases
ATGACCCGTTTTTCCGCCCTGTCGATTTTGAAGAATGCGCTGATCGGCAACACCGGTTGGAGGGAGCAATGGCCCGAATC
CCAGCCGAAAGCGGAATATGATGTCGTGATCGTCGGCGCAGGCGGGCATGGGCTGGGCGCGGCCTATTACCTGGCCAAGG
AGCATGGGATCACCAATGTCGCGGTGATCGACAAAGGCTGGCTCGGCGGCGGGAATACAGGACGCAACACGACCATCATC
CGTTCCAACTACCTCTATGACGAAAGCGCCCGGCTTTATGACCATGCGCTCGATTTGTGGGACGGGCTGAGCCAGGAATT
GAATTACAACGTCATGTACTCGAAGCGCGGCGTGATGATGCTGGCGCATAACGTGCATGATGTTCAGAGTTTTCAGCGGC
ATATCCACTCGAACCGCCTCAACGGCGTCGACAACCGTTGGCTCACCCCCGAAGAGGCGAAGGCATATTGCCCGCCGCTC
AACATCTCGAAGAGCGCGCGTTACCCGGTTATGGGTGCAGCGCTGCAGAAGCGTGCGGGCACCGCACGGCATGACGCGGT
TGCCTGGGGTTATGCGCGCGGCGCTGCGATGCGTGGCGTGGATATTATCCAGAACTGCCCGGTTACCGCTATCCGCCGCG
GCCCGGATGGGCGGGTGACCGGCGTGGAGACTGCGAAGGGCTTCATCAGGGCCAAGAAGGTGGGCGTTTCGGCCGCGAGC
AACACCACGGTTGTCATGGACAGTGCGGGGGTGAGGCTGCCGATCGAGAGCTTCCCGTTGCAGGCGCTCGTTTCAGAACC
TGTGAAGCCAATCTTCCCTTGTGTCGTGATGTCGAACACGGTGCACGCCTATATCAGCCAGTCCGACAAGGGCGAGCTGG
TGATTGGTTCGGGTACCGACCAGTACACCAGCTATTCGCAGCGCGGCGGCCTTCCGCTGATCGAACATACGATTGCGGCG
ATCTGCGAGATTTTCCCGATCTTCACCCGCATGCGGATGCTGCGCAACTGGGGCGGCATCGTTGATGTGACGCCCGATCG
CTCGCCGATCCTTGGCAAGACGCCGGTGCCAGGGCTCTATGTCAACTGTGGTTGGGGCACGGGCGGATTCAAGGCCACGC
CTGGGTCCGCGCATGTGTTTGCCTGGACCATCGCCAAGGACGAGCCGCACCCGGTCAACGCGCCGTTCACGCTCGAACGC
TTCCGCGCCGGTCGCCTCATCGATGAAGCCGCTGCGGCGGCCGTTGCCCATTGA

Upstream 100 bases:

>100_bases
TGGCGCAATAATAACGCCAGTTTGACGCAATGATCCAGTCTTCCGCGCGCTCTTTTGCATAGGGTGCAAGCACGGCAGTT
TCTGCCGCAAGGAAGGCGCC

Downstream 100 bases:

>100_bases
GGACACCATGCTGCTCATTCACTGCCCCTATTGCGACGAGACCCTGCCCGAGCTGGAATTCACCTATGCCGGTGAGGCCC
ACATTGCCCGGCCCGCAAAT

Product: sarcosine oxidase beta subunit family protein

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTRFSALSILKNALIGNTGWREQWPESQPKAEYDVVIVGAGGHGLGAAYYLAKEHGITNVAVIDKGWLGGGNTGRNTTII
RSNYLYDESARLYDHALDLWDGLSQELNYNVMYSKRGVMMLAHNVHDVQSFQRHIHSNRLNGVDNRWLTPEEAKAYCPPL
NISKSARYPVMGAALQKRAGTARHDAVAWGYARGAAMRGVDIIQNCPVTAIRRGPDGRVTGVETAKGFIRAKKVGVSAAS
NTTVVMDSAGVRLPIESFPLQALVSEPVKPIFPCVVMSNTVHAYISQSDKGELVIGSGTDQYTSYSQRGGLPLIEHTIAA
ICEIFPIFTRMRMLRNWGGIVDVTPDRSPILGKTPVPGLYVNCGWGTGGFKATPGSAHVFAWTIAKDEPHPVNAPFTLER
FRAGRLIDEAAAAAVAH

Sequences:

>Translated_417_residues
MTRFSALSILKNALIGNTGWREQWPESQPKAEYDVVIVGAGGHGLGAAYYLAKEHGITNVAVIDKGWLGGGNTGRNTTII
RSNYLYDESARLYDHALDLWDGLSQELNYNVMYSKRGVMMLAHNVHDVQSFQRHIHSNRLNGVDNRWLTPEEAKAYCPPL
NISKSARYPVMGAALQKRAGTARHDAVAWGYARGAAMRGVDIIQNCPVTAIRRGPDGRVTGVETAKGFIRAKKVGVSAAS
NTTVVMDSAGVRLPIESFPLQALVSEPVKPIFPCVVMSNTVHAYISQSDKGELVIGSGTDQYTSYSQRGGLPLIEHTIAA
ICEIFPIFTRMRMLRNWGGIVDVTPDRSPILGKTPVPGLYVNCGWGTGGFKATPGSAHVFAWTIAKDEPHPVNAPFTLER
FRAGRLIDEAAAAAVAH
>Mature_416_residues
TRFSALSILKNALIGNTGWREQWPESQPKAEYDVVIVGAGGHGLGAAYYLAKEHGITNVAVIDKGWLGGGNTGRNTTIIR
SNYLYDESARLYDHALDLWDGLSQELNYNVMYSKRGVMMLAHNVHDVQSFQRHIHSNRLNGVDNRWLTPEEAKAYCPPLN
ISKSARYPVMGAALQKRAGTARHDAVAWGYARGAAMRGVDIIQNCPVTAIRRGPDGRVTGVETAKGFIRAKKVGVSAASN
TTVVMDSAGVRLPIESFPLQALVSEPVKPIFPCVVMSNTVHAYISQSDKGELVIGSGTDQYTSYSQRGGLPLIEHTIAAI
CEIFPIFTRMRMLRNWGGIVDVTPDRSPILGKTPVPGLYVNCGWGTGGFKATPGSAHVFAWTIAKDEPHPVNAPFTLERF
RAGRLIDEAAAAAVAH

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=397, Percent_Identity=23.9294710327456, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI21361378, Length=397, Percent_Identity=23.9294710327456, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI24797151, Length=387, Percent_Identity=21.7054263565891, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 45309; Mature: 45178

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRFSALSILKNALIGNTGWREQWPESQPKAEYDVVIVGAGGHGLGAAYYLAKEHGITNV
CCCHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEHHHCCCEEE
AVIDKGWLGGGNTGRNTTIIRSNYLYDESARLYDHALDLWDGLSQELNYNVMYSKRGVMM
EEEECCCCCCCCCCCCEEEEEECEEECCCHHHHHHHHHHHHHHHHHCCCEEEEECCCEEE
LAHNVHDVQSFQRHIHSNRLNGVDNRWLTPEEAKAYCPPLNISKSARYPVMGAALQKRAG
EECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCC
TARHDAVAWGYARGAAMRGVDIIQNCPVTAIRRGPDGRVTGVETAKGFIRAKKVGVSAAS
CCHHHHEEEHHHCCCHHCCHHHHHCCCEEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCC
NTTVVMDSAGVRLPIESFPLQALVSEPVKPIFPCVVMSNTVHAYISQSDKGELVIGSGTD
CCEEEEECCCCCCCHHHCCHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCEEEECCCC
QYTSYSQRGGLPLIEHTIAAICEIFPIFTRMRMLRNWGGIVDVTPDRSPILGKTPVPGLY
HHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCEE
VNCGWGTGGFKATPGSAHVFAWTIAKDEPHPVNAPFTLERFRAGRLIDEAAAAAVAH
EECCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TRFSALSILKNALIGNTGWREQWPESQPKAEYDVVIVGAGGHGLGAAYYLAKEHGITNV
CCHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEHHHCCCEEE
AVIDKGWLGGGNTGRNTTIIRSNYLYDESARLYDHALDLWDGLSQELNYNVMYSKRGVMM
EEEECCCCCCCCCCCCEEEEEECEEECCCHHHHHHHHHHHHHHHHHCCCEEEEECCCEEE
LAHNVHDVQSFQRHIHSNRLNGVDNRWLTPEEAKAYCPPLNISKSARYPVMGAALQKRAG
EECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCC
TARHDAVAWGYARGAAMRGVDIIQNCPVTAIRRGPDGRVTGVETAKGFIRAKKVGVSAAS
CCHHHHEEEHHHCCCHHCCHHHHHCCCEEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCC
NTTVVMDSAGVRLPIESFPLQALVSEPVKPIFPCVVMSNTVHAYISQSDKGELVIGSGTD
CCEEEEECCCCCCCHHHCCHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCEEEECCCC
QYTSYSQRGGLPLIEHTIAAICEIFPIFTRMRMLRNWGGIVDVTPDRSPILGKTPVPGLY
HHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCEE
VNCGWGTGGFKATPGSAHVFAWTIAKDEPHPVNAPFTLERFRAGRLIDEAAAAAVAH
EECCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]