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The map label for this gene is pqqL [C]

Identifier: 110632791

GI number: 110632791

Start: 475423

End: 476784

Strand: Direct

Name: pqqL [C]

Synonym: Meso_0430

Alternate gene names: 110632791

Gene position: 475423-476784 (Clockwise)

Preceding gene: 110632790

Following gene: 110632792

Centisome position: 10.77

GC content: 61.45

Gene sequence:

>1362_bases
ATGAGATTTTTATCCTTTATCGCCGCATTCCTGATTGTCGCCGCGGCAAGCTTGCCCCAGGCTTCCGCTCAAAGTTCCCC
CGACGTCTTCGAGGCCGAGACCTTCTCGCTCGAAAACGGGCTGCAGGTCGTCGTCATCCCGCAGCGGCGGGTGCCGGTCG
TGACGCATATCCTTTTCTACAAGGCCGGAGGCGCTGACGAGGAAAGGGGGCAGTCGGGCATCGCGCATTTTTTTGAGCAC
TTGATGTTCAAGGCCACGAAAAACCACGAGGCCGGCGCGTTCGAGGCCGCGGTAAAGGCGGTGGGCGGCAGTCAAAATGC
CTTCACCACCAGCGATTTCACCGCCTATTTCGAGCAGGTGCCGCCGAGTGCGCTCAAGGATATGATGGCATTCGAGGCCG
ACCGCATGCGGAACCTTGTTCTGAGCGACGATGCAATCGAGACCGAGCGGCGCGTGGTGATGGAGGAGCGCCTGATGCGG
GTCGACAACGACCCGTCCGGCATCCTGCGTGAGGCGGTGGGCGCCAATCTTTTTCACAACCATCCCTACGGCACGCCCGT
CATCGGGTGGATGCACGAAATCGAGAAACTGACGAAAGAGCAGCTCCAGACCTTCTACGATCGTTACTATCGCCCCAACA
ACGCGGTCCTGGTGGTCGCCGGTGACGTGGATGCGGAAACGGTCCGCAAGCTCGCCGAGGAAACCTATGGCAAGCTGGAA
CGCGGGCCCGACCTGCCGCCCCGTATTCGCCCCATGGAGCCCGATCTCAAGGTGGAGCAGGTGGTGATCCTGCGCGATCC
CCGTGTGACGTTGCCCTCTTTTTCGCGTAACTGGTTCGGCCCGGCGCCATTTGGCGAGAACGAGCAGGACGCCGATGCGC
TCGTGCTCCTTTCCACGATCCTCGGCGGCGGCGAGCGCAGCAGGCTTCACCAGGAATTGGTGGTGAAGAGGCAGATCGCG
TCTTCCGCCGGAGCATGGACCTCCATGAATCTCCGCGATTATTCGCAAATGGGCGTCTACGCCTCGCCCATAGATCCGGA
CAAGTTGCGCGAGGTGCAGCAGGCCGTGGACAAGGAAATCGAGAAGATGGCATCCGAAAACGTGTCCGAGCACGAGCTCG
AGACTGCTAAGAAGGTGCTGGCGAGCCAGCTCATCTTCTCCTGGGAAAGACAGATGTCGCGCGCCCTGGAAGTAGGTACG
ACGCTGATGGTGGGCGGCACGCTCGATGACGTCGCATCGATCCGCGAGCGCATCGATGCGGTGACGGCCGATCAGATCCG
TGAAGCAGCGCAGCGCTACCTGTCGGTTCGCCGCAGCGTGGCCGGTTATCTCCTTCCCGTCGATGCGGAGGACCCGGCAT
GA

Upstream 100 bases:

>100_bases
ATCGTCAGAGTTTAGCCACAAGAGGCGTGGTACATCTTCCGCTCCGCAATCAGCCGGGTGCTGACGCGCGGCTGATCGAA
AGGCTGAACAGGTCATTTGA

Downstream 100 bases:

>100_bases
GAATCGAAAGAACCGCATTGGCCATGGTCATGAAAGCATCACATCGCACTTGCCTGCGGGCGATGTCGCTCGGACTGGTT
CTGTTTGCCCTTGTCCTTCC

Product: peptidase M16-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MRFLSFIAAFLIVAAASLPQASAQSSPDVFEAETFSLENGLQVVVIPQRRVPVVTHILFYKAGGADEERGQSGIAHFFEH
LMFKATKNHEAGAFEAAVKAVGGSQNAFTTSDFTAYFEQVPPSALKDMMAFEADRMRNLVLSDDAIETERRVVMEERLMR
VDNDPSGILREAVGANLFHNHPYGTPVIGWMHEIEKLTKEQLQTFYDRYYRPNNAVLVVAGDVDAETVRKLAEETYGKLE
RGPDLPPRIRPMEPDLKVEQVVILRDPRVTLPSFSRNWFGPAPFGENEQDADALVLLSTILGGGERSRLHQELVVKRQIA
SSAGAWTSMNLRDYSQMGVYASPIDPDKLREVQQAVDKEIEKMASENVSEHELETAKKVLASQLIFSWERQMSRALEVGT
TLMVGGTLDDVASIRERIDAVTADQIREAAQRYLSVRRSVAGYLLPVDAEDPA

Sequences:

>Translated_453_residues
MRFLSFIAAFLIVAAASLPQASAQSSPDVFEAETFSLENGLQVVVIPQRRVPVVTHILFYKAGGADEERGQSGIAHFFEH
LMFKATKNHEAGAFEAAVKAVGGSQNAFTTSDFTAYFEQVPPSALKDMMAFEADRMRNLVLSDDAIETERRVVMEERLMR
VDNDPSGILREAVGANLFHNHPYGTPVIGWMHEIEKLTKEQLQTFYDRYYRPNNAVLVVAGDVDAETVRKLAEETYGKLE
RGPDLPPRIRPMEPDLKVEQVVILRDPRVTLPSFSRNWFGPAPFGENEQDADALVLLSTILGGGERSRLHQELVVKRQIA
SSAGAWTSMNLRDYSQMGVYASPIDPDKLREVQQAVDKEIEKMASENVSEHELETAKKVLASQLIFSWERQMSRALEVGT
TLMVGGTLDDVASIRERIDAVTADQIREAAQRYLSVRRSVAGYLLPVDAEDPA
>Mature_453_residues
MRFLSFIAAFLIVAAASLPQASAQSSPDVFEAETFSLENGLQVVVIPQRRVPVVTHILFYKAGGADEERGQSGIAHFFEH
LMFKATKNHEAGAFEAAVKAVGGSQNAFTTSDFTAYFEQVPPSALKDMMAFEADRMRNLVLSDDAIETERRVVMEERLMR
VDNDPSGILREAVGANLFHNHPYGTPVIGWMHEIEKLTKEQLQTFYDRYYRPNNAVLVVAGDVDAETVRKLAEETYGKLE
RGPDLPPRIRPMEPDLKVEQVVILRDPRVTLPSFSRNWFGPAPFGENEQDADALVLLSTILGGGERSRLHQELVVKRQIA
SSAGAWTSMNLRDYSQMGVYASPIDPDKLREVQQAVDKEIEKMASENVSEHELETAKKVLASQLIFSWERQMSRALEVGT
TLMVGGTLDDVASIRERIDAVTADQIREAAQRYLSVRRSVAGYLLPVDAEDPA

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=440, Percent_Identity=23.1818181818182, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI46593007, Length=437, Percent_Identity=24.0274599542334, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI1787770, Length=231, Percent_Identity=29.004329004329, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71999683, Length=440, Percent_Identity=24.5454545454545, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17553678, Length=430, Percent_Identity=25.3488372093023, Blast_Score=102, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323192, Length=419, Percent_Identity=25.2983293556086, Blast_Score=103, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6321813, Length=432, Percent_Identity=21.5277777777778, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21357875, Length=419, Percent_Identity=23.8663484486874, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24646943, Length=419, Percent_Identity=23.8663484486874, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI19921772, Length=433, Percent_Identity=24.2494226327945, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 50471; Mature: 50471

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLSFIAAFLIVAAASLPQASAQSSPDVFEAETFSLENGLQVVVIPQRRVPVVTHILFY
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEECCCCCEEEEECCCCCCHHHHHHHH
KAGGADEERGQSGIAHFFEHLMFKATKNHEAGAFEAAVKAVGGSQNAFTTSDFTAYFEQV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHC
PPSALKDMMAFEADRMRNLVLSDDAIETERRVVMEERLMRVDNDPSGILREAVGANLFHN
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHCC
HPYGTPVIGWMHEIEKLTKEQLQTFYDRYYRPNNAVLVVAGDVDAETVRKLAEETYGKLE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
RGPDLPPRIRPMEPDLKVEQVVILRDPRVTLPSFSRNWFGPAPFGENEQDADALVLLSTI
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LGGGERSRLHQELVVKRQIASSAGAWTSMNLRDYSQMGVYASPIDPDKLREVQQAVDKEI
HCCCHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
EKMASENVSEHELETAKKVLASQLIFSWERQMSRALEVGTTLMVGGTLDDVASIRERIDA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHH
VTADQIREAAQRYLSVRRSVAGYLLPVDAEDPA
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
>Mature Secondary Structure
MRFLSFIAAFLIVAAASLPQASAQSSPDVFEAETFSLENGLQVVVIPQRRVPVVTHILFY
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEECCCCCEEEEECCCCCCHHHHHHHH
KAGGADEERGQSGIAHFFEHLMFKATKNHEAGAFEAAVKAVGGSQNAFTTSDFTAYFEQV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHC
PPSALKDMMAFEADRMRNLVLSDDAIETERRVVMEERLMRVDNDPSGILREAVGANLFHN
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHCC
HPYGTPVIGWMHEIEKLTKEQLQTFYDRYYRPNNAVLVVAGDVDAETVRKLAEETYGKLE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
RGPDLPPRIRPMEPDLKVEQVVILRDPRVTLPSFSRNWFGPAPFGENEQDADALVLLSTI
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LGGGERSRLHQELVVKRQIASSAGAWTSMNLRDYSQMGVYASPIDPDKLREVQQAVDKEI
HCCCHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
EKMASENVSEHELETAKKVLASQLIFSWERQMSRALEVGTTLMVGGTLDDVASIRERIDA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHH
VTADQIREAAQRYLSVRRSVAGYLLPVDAEDPA
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]